octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Starvation D013217 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Memory Disorders D008569 33 associated lipids
Hypothyroidism D007037 32 associated lipids
Diarrhea D003967 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Obesity D009765 29 associated lipids
Endotoxemia D019446 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Poultry Diseases D011201 21 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Hemorrhage D006470 15 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Reye Syndrome D012202 14 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Chronic Disease D002908 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Asthenia D001247 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Schoonjans R et al. The 13C-octanoic acid breath test: validation of a new noninvasive method of measuring gastric emptying in rats. 2002 Neurogastroenterol. Motil. pmid:12061914
Babu E et al. Role of human organic anion transporter 4 in the transport of ochratoxin A. 2002 Biochim. Biophys. Acta pmid:12063169
Sun CQ et al. The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. 2002 Chem. Biol. Interact. pmid:12076524
Jørgensen JR et al. Absorption and metabolism of octanoate by the rat colon in vivo: concentration dependency and influence of alternative fuels. 2002 Gut pmid:12077096
Jelen HH et al. Influence of octanoic acid addition to medium on some volatile compounds and PR-toxin biosynthesis by Penicillium roqueforti. 2002 Lett. Appl. Microbiol. pmid:12081547
Robertson MD et al. Acute ingestion of a meal rich in n-3 polyunsaturated fatty acids results in rapid gastric emptying in humans. 2002 Am. J. Clin. Nutr. pmid:12081840
Watanabe Y et al. Suppressive effect of saturated acyl L-ascorbate on the oxidation of linoleic acid encapsulated with maltodextrin or gum arabic by spray-drying. 2002 J. Agric. Food Chem. pmid:12083870
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Leite-Moreira AF et al. Modulation of myocardial function by pyruvate. 2002 Rev Port Cardiol pmid:12090129
García-Villafranca J and Castro J Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. 2002 Biochem. Pharmacol. pmid:12093476
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Bender JL et al. Site-isolated luminescent europium complexes with polyester macroligands: metal-centered heteroarm stars and nanoscale assemblies with labile block junctions. 2002 J. Am. Chem. Soc. pmid:12121083
Dichtelmüller H et al. Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. 2002 Biologicals pmid:12127315
García M et al. Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. 2002 Biologicals pmid:12127316
Korneyeva M et al. Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. 2002 Biologicals pmid:12127317
Banks WA et al. Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. 2002 J. Pharmacol. Exp. Ther. pmid:12130749
Chassard D et al. Effects of subhypnotic doses of propofol on gastric emptying in volunteers. 2002 Anesthesiology pmid:12131109
Gwak HS et al. Effect of vehicles and enhancers on the in vitro permeation of melatonin through hairless mouse skin. 2002 Arch. Pharm. Res. pmid:12135116
Bromer MQ et al. Simultaneous measurement of gastric emptying with a simple muffin meal using [13C]octanoate breath test and scintigraphy in normal subjects and patients with dyspeptic symptoms. 2002 Dig. Dis. Sci. pmid:12141833
Wilk PJ et al. Failure of intestinal lymphatic block to prevent experimental hypercholesterolemia. 1975 Lymphology pmid:1214506