octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hollander D | Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. | 1980 | Am. J. Physiol. | pmid:7435575 |
Patel TB | Effect of sulfonylureas on hepatic fatty acid oxidation. | 1986 | Am. J. Physiol. | pmid:3090894 |
Maes BD et al. | Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. | 1998 | Am. J. Physiol. | pmid:9655697 |
Chen TM et al. | Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. | 1997 | Am. J. Physiol. | pmid:9374750 |
Adams SH and Odle J | Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. | 1993 | Am. J. Physiol. | pmid:8238444 |
Vincent G et al. | Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10780941 |
Kim JY et al. | Lipid oxidation is reduced in obese human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052958 |
Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
Bando M et al. | Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22114024 |
Turcotte LP et al. | High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739099 |