octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Constantinides PP et al. | Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. | 1996 | Pharm. Res. | pmid:8932438 |
Sidossis LS et al. | Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. | 1996 | J. Clin. Invest. | pmid:8941640 |
Yang H et al. | Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. | 1996 | Ann. N. Y. Acad. Sci. | pmid:8958099 |
Kuge Y et al. | [1-11C]octanoate as a potential PET tracer for studying glial functions: PET evaluation in rats and cats. | 1996 | Nucl. Med. Biol. | pmid:9004290 |
Yamazaki S et al. | Uptake of radioactive octanoate in astrocytoma cells: basic studies for application of [11C]octanoate as a PET tracer. | 1996 | Ann Nucl Med | pmid:9006724 |
Trotter PJ et al. | Fatty acid uptake by Caco-2 human intestinal cells. | 1996 | J. Lipid Res. | pmid:9026531 |
Bikhazi AB et al. | Calcium-prostaglandin aggregation and its effect on prostaglandin uptake by isolated rabbit intestine. | 1977 | J Pharm Sci | pmid:903871 |
Viegas CA and Sá-Correia I | Effects of low temperatures (9-33 degrees C) and pH (3.3-5.7) in the loss of Saccharomyces cerevisiae viability by combining lethal concentrations of ethanol with octanoic and decanoic acids. | 1997 | Int. J. Food Microbiol. | pmid:9039572 |
Priestman DA et al. | Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes. | 1997 | Biochem. Soc. Trans. | pmid:9056999 |
Schadewaldt P et al. | Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS). | 1997 | Clin. Chem. | pmid:9068597 |