octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Starvation D013217 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Memory Disorders D008569 33 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Endotoxemia D019446 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Poultry Diseases D011201 21 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Hemorrhage D006470 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Campylobacter Infections D002169 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Critical Illness D016638 13 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Chronic Disease D002908 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Tong HF et al. Caprylate as the albumin-selective modifier to improve IgG purification with hydrophobic charge-induction chromatography. 2013 J Chromatogr A pmid:23473512
Lim CH et al. Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. 2013 World J. Gastroenterol. pmid:23885150
Scott G et al. Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. 2013 Langmuir pmid:24144273
Zimmermann S et al. Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. 2012 Jan-Mar Sci Pharm pmid:22396915
Morais V and Massaldi H A model mechanism for protein precipitation by caprylic acid: application to plasma purification. 2012 Jan-Feb Biotechnol. Appl. Biochem. pmid:22332745
Brun AC et al. The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. 2012 Clin Nutr pmid:21835514
Fernández J et al. Synthesis, structure and properties of poly(L-lactide-co-ε-caprolactone) statistical copolymers. 2012 J Mech Behav Biomed Mater pmid:22498288
Lockman KA et al. Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. 2012 Liver Int. pmid:22429485
Molinas A et al. Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. 2012 PLoS ONE pmid:22563480
Pereira RF et al. What drives the precipitation of long-chain calcium carboxylates (soaps) in aqueous solution? 2012 Phys Chem Chem Phys pmid:22513819
Rucinski M et al. Evidence suggesting that ghrelin O-acyl transferase inhibitor acts at the hypothalamus to inhibit hypothalamo-pituitary-adrenocortical axis function in the rat. 2012 Peptides pmid:22543218
Simon-Colin C et al. Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. 2012 Int. J. Biol. Macromol. pmid:22947450
Ogungbenro K and Aarons L A semi-mechanistic gastric emptying pharmacokinetic model for (13)C-octanoic acid: an evaluation using simulation. 2012 Eur J Pharm Sci pmid:22155547
Otero-Patiño R et al. Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. 2012 Toxicon pmid:22146491
Abdolmohammadi S et al. Enhancement of mechanical and thermal properties of polycaprolactone/chitosan blend by calcium carbonate nanoparticles. 2012 Int J Mol Sci pmid:22605993
Kube M et al. Current view on phytoplasma genomes and encoded metabolism. 2012 ScientificWorldJournal pmid:22550465
Wood P Human normal immunoglobulin in the treatment of primary immunodeficiency diseases. 2012 Ther Clin Risk Manag pmid:22547934
Andersen JT et al. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. 2012 Nat Commun pmid:22215085
Maletínská L et al. Characterization of new stable ghrelin analogs with prolonged orexigenic potency. 2012 J. Pharmacol. Exp. Ther. pmid:22182933
Goh YS and Tan IK Polyhydroxyalkanoate production by antarctic soil bacteria isolated from Casey Station and Signy Island. 2012 Microbiol. Res. pmid:21945102