octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zaleski J and Bryla J | Effects of oleate, palmitate, and octanoate on gluconeogenesis in isolated rabbit liver cells. | 1977 | Arch. Biochem. Biophys. | pmid:921276 |
Jones JG et al. | Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. | 1997 | Anal. Biochem. | pmid:9212871 |
Leclercq P et al. | Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. | 1997 | Biochem. J. | pmid:9230136 |
Rabinowitz JL et al. | A method for serum octanoate in hepatic cirrhosis and hepatic encephalopathy. | 1977 | Clin. Chem. | pmid:923071 |
Coyle EF et al. | Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. | 1997 | Am. J. Physiol. | pmid:9277379 |
Fowler JS et al. | Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo. | 1976 | J. Pharmacol. Exp. Ther. | pmid:933003 |
Sheikh MI | Renal handling of phenol red. II. The mechanism of substituted phenolsulphophthalein (PSP) dye transport in rabbit kidney tubules in vitro. | 1976 | J. Physiol. (Lond.) | pmid:933027 |
Bito LZ et al. | Inhibition of in vitro concentrative prostaglandin accumulation by prostaglandins, prostaglandin analogues and by some inhibitors of organic anion transport. | 1976 | J. Physiol. (Lond.) | pmid:933072 |
Gann VK and Hardin CD | Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. | 1997 | Physiol Chem Phys Med NMR | pmid:9353955 |
Chen TM et al. | Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. | 1997 | Am. J. Physiol. | pmid:9374750 |
Andreev LV and Temnov AV | [Determination of the specificity of microbial esterases in vivo]. | 1976 Jan-Feb | Mikrobiologiia | pmid:940489 |
Guillot E et al. | Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification. | 1997 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9440218 |
Choi MG et al. | Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. | 1998 | Am. J. Gastroenterol. | pmid:9448183 |
Barron JT et al. | Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. | 1997 | Biochim. Biophys. Acta | pmid:9452767 |
Hillgartner FB and Charron T | Arachidonate and medium-chain fatty acids inhibit transcription of the acetyl-CoA carboxylase gene in hepatocytes in culture. | 1997 | J. Lipid Res. | pmid:9458278 |
Viegas CA et al. | The H(+)-ATPase in the plasma membrane of Saccharomyces cerevisiae is activated during growth latency in octanoic acid-supplemented medium accompanying the decrease in intracellular pH and cell viability. | 1998 | Appl. Environ. Microbiol. | pmid:9464423 |
Visarius TM et al. | Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats. | 1998 | Drug Metab. Dispos. | pmid:9492379 |
Groves CE et al. | Peritubular transport of ochratoxin A in rabbit renal proximal tubules. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9495853 |
Sidossis LS et al. | Regulation of fatty acid oxidation in untrained vs. trained men during exercise. | 1998 | Am. J. Physiol. | pmid:9530135 |
Abdel-aleem S et al. | Regulation of carbohydrate and fatty acid utilization by L-carnitine during cardiac development and hypoxia. | 1998 | Mol. Cell. Biochem. | pmid:9546635 |