octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
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Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tenreiro S et al. | AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11922628 |
| Torres-Guzmán R et al. | Substrate specificity of penicillin acylase from Streptomyces lavendulae. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11855830 |
| Yamato M et al. | Exogenous administration of octanoic acid accelerates octanoylated ghrelin production in the proventriculus of neonatal chicks. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15953586 |
| Ohgusu H et al. | Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19501572 |
| Jones PM et al. | Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16750167 |
| Bjorge SM and Baillie TA | Inhibition of medium-chain fatty acid beta-oxidation in vitro by valproic acid and its unsaturated metabolite, 2-n-propyl-4-pentenoic acid. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3933498 |
| Maddaiah VT | Ammonium inhibition of fatty acid oxidation in rat liver mitochondria. A possible cause of fatty liver in Reye's syndrome and urea cycle defects. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3977937 |
| May JM et al. | Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16650819 |
| Shanado Y et al. | Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15555596 |
| Matsumoto M et al. | Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11549267 |
| Olivieri MC and Botelho LH | Synergistic inhibition of hepatic ketogenesis in the presence of insulin and a cAMP antagonist. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2539126 |
| Suzuki S et al. | Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23376076 |
| Oettl K et al. | An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767923 |
| Tsai CS and al-Kassim LS | Multifunctional activities of pickerel liver alcohol dehydrogenase. | 1993 Sep-Oct | Biochem. Cell Biol. | pmid:8192894 |
| Palabost-Charles L | Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. | 1982 | Biochem. Genet. | pmid:6810873 |
| Bijlsma R | Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. | 1980 | Biochem. Genet. | pmid:6781470 |
| Blumenthal SA | Inhibition of gluconeogenesis in rat liver by lipoic acid. Evidence for more than one site of action. | 1984 | Biochem. J. | pmid:6430273 |
| Pégorier JP et al. | Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. | 1983 | Biochem. J. | pmid:6870859 |
| Leclercq P et al. | Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. | 1997 | Biochem. J. | pmid:9230136 |
| Soboll S et al. | Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. | 1984 | Biochem. J. | pmid:6743276 |