octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
Eder M et al. | Pharmacokinetic properties of peptidic radiopharmaceuticals: reduced uptake of (EH)3-conjugates in important organs. | 2013 | J. Nucl. Med. | pmid:23804326 |
Harmancey R et al. | Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. | 2013 | FASEB J. | pmid:23825227 |
Chiang SH et al. | Limits of medium-chain and long-chain triacylglycerol utilization by neonatal piglets. | 1990 | J. Anim. Sci. | pmid:2384363 |
Lim CH et al. | Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. | 2013 | World J. Gastroenterol. | pmid:23885150 |
Morton DH and Kelley RI | Diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency in the neonatal period by measurement of medium-chain fatty acids in plasma and filter paper blood samples. | 1990 | J. Pediatr. | pmid:2391601 |
Corona-Castañeda B et al. | Modulators of antibiotic activity from Ipomoea murucoides. | 2013 | Phytochemistry | pmid:23920226 |
Guo H et al. | Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24018188 |
Hungate EA et al. | A locus in Drosophila sechellia affecting tolerance of a host plant toxin. | 2013 | Genetics | pmid:24037270 |
Choi MJ et al. | New decontamination method based on caprylic acid in combination with citric acid or vanillin for eliminating Cronobacter sakazakii and Salmonella enterica serovar Typhimurium in reconstituted infant formula. | 2013 | Int. J. Food Microbiol. | pmid:24042002 |
Horner KM et al. | Reproducibility of gastric emptying in overweight and obese males. | 2014 | Clin Nutr | pmid:24074547 |
Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
Scott G et al. | Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. | 2013 | Langmuir | pmid:24144273 |
de Oliveira AL et al. | Adrenergic metabolic and hemodynamic effects of octopamine in the liver. | 2013 | Int J Mol Sci | pmid:24196353 |
Zhang JF et al. | A new derivatization method to enhance sensitivity for the determination of low levels of valproic acid in human plasma. | J Chromatogr Sci | pmid:24243686 | |
Al-Abdulla I et al. | Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. | 2014 | J. Immunol. Methods | pmid:24246428 |
Lee YC and Johnson JH | Determination of sodium caprylate in plasma volume expanders by gas chromatography. | 1986 | J. Chromatogr. | pmid:2426293 |
Bokhout BA et al. | Porcine IgG. Isolation of two IgG-subclasses and anti-IgG class- and subclass-specific antibodies. | 1986 | Mol. Immunol. | pmid:2427943 |
Antón MJ et al. | Aromatic profile of ciders by chemical quantitative, gas chromatography-olfactometry, and sensory analysis. | 2014 | J. Food Sci. | pmid:24313985 |
Shilling M et al. | Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. | 2013 | J Med Food | pmid:24328700 |
Kössler F and Nasledov GA | Effects of Na-octanoate on potassium contractures in normal and denervated frog tonic fibres. | 1986 | Gen. Physiol. Biophys. | pmid:2433184 |
Qin XL et al. | Fatty acid specificity of T1 lipase and its potential in acylglycerol synthesis. | 2014 | J. Sci. Food Agric. | pmid:24338705 |
Gadotti C et al. | Inhibitory effect of combinations of caprylic acid and nisin on Listeria monocytogenes in queso fresco. | 2014 | Food Microbiol. | pmid:24387845 |
Bruno G et al. | 13C-octanoic acid breath test to study gastric emptying time. | 2013 | Eur Rev Med Pharmacol Sci | pmid:24443070 |
Paulsen SJ et al. | Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. | 2014 | PLoS ONE | pmid:24520357 |
Kajimoto M et al. | Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531815 |
Ke L et al. | Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. | 2014 | Crit Care Resusc | pmid:24588433 |
Chen YJ et al. | Production and characterization of medium-chain-length polyhydroxyalkanoates by Pseudomonas mosselii TO7. | 2014 | J. Biosci. Bioeng. | pmid:24630613 |
Librán-Pérez M et al. | Central administration of oleate or octanoate activates hypothalamic fatty acid sensing and inhibits food intake in rainbow trout. | 2014 | Physiol. Behav. | pmid:24631300 |
Morais V et al. | Immunoglobulin purification by caprylic acid. | 2014 | Methods Mol. Biol. | pmid:24648074 |
Marquez A et al. | Optimization and validation of an automated DHS-TD-GC-MS method for the determination of aromatic esters in sweet wines. | 2014 | Talanta | pmid:24725861 |
Tao Y et al. | Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. | 2014 | Enzyme Microb. Technol. | pmid:24731826 |
Layek B and Singh J | N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. | 2012 | Carbohydr Polym | pmid:24750737 |
Adamczak M | Characteristic of fungal lipases and their application in synthesis of structered lipids. | 2003 | Commun. Agric. Appl. Biol. Sci. | pmid:24757817 |
Darling RA et al. | Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24760994 |
Lavieri NA et al. | Investigating the control of Listeria monocytogenes on alternatively-cured frankfurters using natural antimicrobial ingredients or post-lethality interventions. | 2014 | Meat Sci. | pmid:24769878 |
De Preter V et al. | Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. | 2015 | Gut | pmid:24811995 |
Lavieri NA et al. | Investigating the control of Listeria monocytogenes on a ready-to-eat ham product using natural antimicrobial ingredients and postlethality interventions. | 2014 | Foodborne Pathog. Dis. | pmid:24824223 |
Sun X et al. | Tuning the self-assembly of oligothiophenes on chemical vapor deposition graphene: effect of functional group, solvent, and substrate. | 2014 | Chem Asian J | pmid:24839081 |
Morimoto K et al. | Effect of medium-chain fatty acid salts on penetration of a hydrophilic compound and a macromolecular compound across rabbit corneas. | 1989 Nov-Dec | Arch Int Pharmacodyn Ther | pmid:2484010 |
Dalgaard L et al. | Resolution and binding site determination of D,L-thyronine by high-performance liquid chromatography using immobilized albumin as chiral stationary phase. Determination of the optical purity of thyroxine in tablets. | 1989 | J Pharm Biomed Anal | pmid:2488636 |
Mitkov D | Octanoate action on muscular protein catabolism in rats. | 1989 | Folia Med (Plovdiv) | pmid:2490157 |
Matsumoto Y et al. | Rectal absorption enhancement of gentamicin in rabbits from hollow type suppositories by sodium salicylate or sodium caprylate. | 1989 | Drug Des. Deliv. | pmid:2490276 |
Salentinig S et al. | pH-responsive micelles based on caprylic acid. | 2014 | Langmuir | pmid:24905895 |
Gasco MR et al. | Microemulsions as topical delivery vehicles: ocular administration of timolol. | 1989 | J Pharm Biomed Anal | pmid:2490750 |
Bagai S et al. | Lipid-modified polyethylenimine-mediated DNA attraction evaluated by molecular dynamics simulations. | 2014 | J Phys Chem B | pmid:24918771 |
el Alaoui-Talibi Z and Moravec J | Carnitine transport and exogenous palmitate oxidation in chronically volume-overloaded rat hearts. | 1989 | Biochim. Biophys. Acta | pmid:2499353 |
Zhu J et al. | The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates. | 2014 | Nutrients | pmid:25010553 |
Jensen GL et al. | Dietary modification of chyle composition in chylothorax. | 1989 | Gastroenterology | pmid:2502466 |
Zieve L and Lyftogt C | Valproic acid induction of coma in rats: synergism with NH4+ and pentobarbital. | 1989 | Metab Brain Dis | pmid:2502706 |
Wolfram G et al. | [Distribution and elimination of medium- and long-chain fatty acids of a fat emulsion in lipoproteins of severely injured patients following bolus injection]. | 1989 | Z Ernahrungswiss | pmid:2503947 |
el Alaoui-Talibi Z and Moravec J | Limitation of long chain fatty acid oxidation in volume over-loaded rat hearts. | 1989 | Adv. Exp. Med. Biol. | pmid:2506741 |
Razmakhnin EV et al. | [The atomic emission analysis under examination of composition of gallstones]. | 2014 | Klin. Lab. Diagn. | pmid:25080794 |
Coenen MJ et al. | Nanostructuring of self-assembled porphyrin networks at a solid/liquid interface: local manipulation under global control. | 2014 | Chemphyschem | pmid:25146424 |
Schubert MM et al. | Coffee for morning hunger pangs. An examination of coffee and caffeine on appetite, gastric emptying, and energy intake. | 2014 | Appetite | pmid:25218717 |
Caballero E et al. | Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases. | 2014 | PLoS ONE | pmid:25248107 |
Cherniavs'kyÄ VV | [Clinical use of 13C-breath tests in esophagogastroduodenal diseases]. | 2014 Mar-Apr | Lik. Sprava | pmid:25286602 |
Chang P et al. | Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. | 2015 | J. Pharmacol. Exp. Ther. | pmid:25326131 |
Nass R et al. | The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. | 2015 | J. Clin. Endocrinol. Metab. | pmid:25337923 |
Sengupta A et al. | Antioxidative effect of rice bran oil and medium chain fatty acid rich rice bran oil in arsenite induced oxidative stress in rats. | 2014 | J Oleo Sci | pmid:25354877 |
Olson JE et al. | Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome. | 1989 | J. Neurochem. | pmid:2538563 |
Marchington DR et al. | Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat hepatocytes. | 1989 | Biochem. J. | pmid:2539088 |
Olivieri MC and Botelho LH | Synergistic inhibition of hepatic ketogenesis in the presence of insulin and a cAMP antagonist. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2539126 |
Goodwin D et al. | Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides. | 2015 | Pharm. Res. | pmid:25407542 |
Skřivanová E et al. | Potential use of caprylic acid in broiler chickens: effect on Salmonella enteritidis. | 2015 | Foodborne Pathog. Dis. | pmid:25407657 |
Wlaź P et al. | Acute anticonvulsant effects of capric acid in seizure tests in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25445478 |
Socała K et al. | Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25455587 |
Vargas M et al. | Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system, caprylic acid precipitation, and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity. | 2015 | Vox Sang. | pmid:25469648 |
Gourcerol G et al. | Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. | 2015 | Aliment. Pharmacol. Ther. | pmid:25523288 |
Azain MJ and Ontko JA | An explanation for decreased ketogenesis in the liver of the obese Zucker rat. | 1989 | Am. J. Physiol. | pmid:2552844 |
Rosenblatt J et al. | Caprylic acid and glyceryl trinitrate combination for eradication of biofilm. | 2015 | Antimicrob. Agents Chemother. | pmid:25534725 |
Kim SA and Rhee MS | Predictive model and optimization of a combined treatment of caprylic acid and citric acid for the reduction of Escherichia coli O157:H7 using the response surface methodology. | 2015 | Int. J. Food Microbiol. | pmid:25544642 |
Xu J et al. | Dual receptor-targeting â¹â¹mTc-labeled Arg-Gly-Asp-conjugated Alpha-Melanocyte stimulating hormone hybrid peptides for human melanoma imaging. | 2015 | Nucl. Med. Biol. | pmid:25577037 |
Jha SK and Hayashi K | A quick responding quartz crystal microbalance sensor array based on molecular imprinted polyacrylic acids coating for selective identification of aldehydes in body odor. | 2015 | Talanta | pmid:25618646 |
Fu Y et al. | Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25620365 |
Obeso JI et al. | The loss of function of PhaC1 is a survival mechanism that counteracts the stress caused by the overproduction of poly-3-hydroxyalkanoates in Pseudomonas putidaΔfadBA. | 2015 | Environ. Microbiol. | pmid:25627209 |
Vidal H et al. | Vasoactive intestinal peptide stimulates long-chain fatty acid oxidation and inhibits acetyl-coenzyme A carboxylase activity in isolated rat enterocytes. | 1989 | J. Biol. Chem. | pmid:2564395 |
Alonso C et al. | Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. | 2015 | J. Pharm. Pharmacol. | pmid:25645286 |
El-Ekiaby M et al. | Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. | 2015 | PLoS Negl Trop Dis | pmid:25719558 |
Sengupta A et al. | Production of medium chain fatty acid rich mustard oil using packed bed bioreactor. | 2015 | J Oleo Sci | pmid:25748375 |
Narayanan A et al. | Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. | 2015 | Int J Mol Sci | pmid:25749477 |
Borrull A et al. | New insights into the toxicity mechanism of octanoic and decanoic acids on Saccharomyces cerevisiae. | 2015 | Yeast | pmid:25773463 |
Xu J et al. | In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. | 2015 | Chem. Commun. (Camb.) | pmid:25792085 |
Royce LA et al. | Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. | 2015 | Metab. Eng. | pmid:25839166 |
Damitz R and Chauhan A | Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. | 2015 | Int J Pharm | pmid:25839419 |
Chen Y et al. | Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. | 2015 | Int J Pharm | pmid:25841571 |
RodrÃguez-Moyá M and Gonzalez R | Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. | 2015 | J Proteomics | pmid:25845584 |
Kim SA and Rhee MS | Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. | 2015 | Food Microbiol. | pmid:25846927 |
Pesce P et al. | Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. | 2015 | J Oral Rehabil | pmid:25882620 |
Arora T et al. | Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission. | 2015 | PLoS ONE | pmid:25946120 |
Coronado MA et al. | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. | 2015 | Curr. Protein Pept. Sci. | pmid:25961401 |
Nishitani N et al. | Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. | 2015 | Chem Asian J | pmid:26033832 |
Epprecht L et al. | Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. | 2015 | J. Neurol. | pmid:26048686 |
Kadota Y et al. | Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. | 2015 | Metab. Clin. Exp. | pmid:26104959 |
Hovorková P and Skřivanová E | Use of Caprylic Acid in Broiler Chickens: Effect on Campylobacter jejuni. | 2015 | Foodborne Pathog. Dis. | pmid:26114373 |
Mohanty JG and Elazhary Y | Purification of IgG from serum with caprylic acid and ammonium sulphate precipitation is not superior to ammonium sulphate precipitation alone. | 1989 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:2612135 |
pmid:26129951 | ||||
Upadhyaya I et al. | Reducing Colonization and Eggborne Transmission of Salmonella Enteritidis in Layer Chickens by In-Feed Supplementation of Caprylic Acid. | 2015 | Foodborne Pathog. Dis. | pmid:26135893 |
Genser B et al. | Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis. | 2015 | Environ Health | pmid:26159541 |
Lemarié F et al. | Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. | 2015 | PLoS ONE | pmid:26196391 |