octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Fulgencio JP et al. | Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes. | 2001 | Biochem. Pharmacol. | pmid:11448453 |
Jørgensen J and Mortensen PB | Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11447021 |
Pi-Sunyer FX | Effect of long- and medium-chain fatty acids on insulin secretion from pieces of rat pancreas. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1144459 |
Beauvieux MC et al. | Butyrate impairs energy metabolism in isolated perfused liver of fed rats. | 2001 | J. Nutr. | pmid:11435518 |
Aguedo M et al. | Intracellular pH-dependent efflux of the fluorescent probe pyranine in the yeast Yarrowia lipolytica. | 2001 | FEMS Microbiol. Lett. | pmid:11425473 |
Bevington A et al. | Leucine suppresses acid-induced protein wasting in L6 rat muscle cells. | 2001 | Eur. J. Clin. Invest. | pmid:11422399 |
Goese M et al. | Biosynthesis of lipstatin. Incorporation of multiply deuterium-labeled (5Z,8Z)-tetradeca-5,8-dienoic acid and octanoic acid. | 2001 | J. Org. Chem. | pmid:11421791 |
Dagher Z et al. | Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells. | 2001 | Circ. Res. | pmid:11420304 |
Morita YS and Englund PT | Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. | 2001 | Mol. Biochem. Parasitol. | pmid:11420102 |
Fulks RM et al. | Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm. | 1975 | J. Biol. Chem. | pmid:1141208 |
Zhou GW et al. | [Esterification of octanoic acid with 1-octanol catalyzed by lipase in W/O microemulsions and in microemulsion-based organogels]. | 2001 | Sheng Wu Gong Cheng Xue Bao | pmid:11411238 |
Karagül-Yüceer Y et al. | Aroma-active components of nonfat dry milk. | 2001 | J. Agric. Food Chem. | pmid:11409991 |
Liu X et al. | [One simple and efficient method for purification of IgG McAb from mice ascites: caprylic acid/ammonium sulfate precipitation]. | 1999 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:11387969 |
Cabral MG et al. | Mechanisms underlying the acquisition of resistance to octanoic-acid-induced-death following exposure of Saccharomyces cerevisiae to mild stress imposed by octanoic acid or ethanol. | 2001 | Arch. Microbiol. | pmid:11382226 |
Sek L et al. | Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis. | 2001 | J Pharm Biomed Anal | pmid:11377046 |
Talley NJ et al. | Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? | 2001 | Am. J. Gastroenterol. | pmid:11374677 |
Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
Money SR and York JW | Development of oral heparin therapy for prophylaxis and treatment of deep venous thrombosis. | 2001 | Cardiovasc Surg | pmid:11336843 |
Ushigome F et al. | Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). | 2001 | Eur. J. Pharmacol. | pmid:11334847 |
Sellappan S and Akoh CC | Synthesis of structured lipids by transesterification of trilinolein catalyzed by Lipozyme IM60. | 2001 | J. Agric. Food Chem. | pmid:11308369 |
Tangen O et al. | Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. | 1975 | Scand. J. Clin. Lab. Invest. | pmid:1129590 |
Vessey DA | Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. | 2001 | Dig. Dis. Sci. | pmid:11281196 |
Briaud I et al. | Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. | 2001 | Diabetes | pmid:11272142 |
Davidson NE et al. | Synthesis, analysis and rearrangement of novel unnatural glucosinolates. | 2001 | Carbohydr. Res. | pmid:11270808 |
Raza S et al. | Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study. | 2001 | Protein Sci. | pmid:11266619 |
Wyse CA et al. | Assessment of the rate of solid-phase gastric emptying in ponies by means of the 13C-octanoic acid breath test: a preliminary study. | 2001 | Equine Vet. J. | pmid:11266071 |
Staeffen J et al. | [Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis. 150 dosages in 61 patients (author's transl)]. | 1979 | Nouv Presse Med | pmid:112576 |
Sibille B et al. | The mitochondrial consequences of uncoupling intact cells depend on the nature of the exogenous substrate. | 2001 | Biochem. J. | pmid:11256968 |
Lu X et al. | [Production, characterization and purification of monoclonal antibodies against antigens of Mycobacterium tuberculosis H37Rv strain]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11225032 |
Plante OJ et al. | Automated solid-phase synthesis of oligosaccharides. | 2001 | Science | pmid:11222853 |
Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
Iwahashi H | High-performance liquid chromatographic determination of linoleic acid peroxide-derived radicals using electrochemical detection. | 2000 | J Chromatogr A | pmid:11204234 |
Kulik W et al. | Improved use of the [13C]octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance. | 2001 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:11204215 |
Gandhi NN and Mukherjee KD | Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases. | 2000 | Biochem. Soc. Trans. | pmid:11171278 |
Taylor SI et al. | Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio. | 1975 | J. Biol. Chem. | pmid:1116996 |
Hosoda H et al. | Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11162448 |
Hoffmann N et al. | Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. | 2000 | Appl. Microbiol. Biotechnol. | pmid:11131392 |
Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
Miller JR et al. | Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein. | 2000 | Biochemistry | pmid:11106496 |
Piett V et al. | Enantioseparation of anionic analytes by non-aqueous capillary electrophoresis using quinine and quinidine derivatives as chiral counter-ions. | 2000 | J Chromatogr A | pmid:11100848 |
Cappello G et al. | Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. | 2000 | Am. J. Gastroenterol. | pmid:11095323 |
Benthem L et al. | Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11093916 |
Lee KT et al. | Nutritional effects of enzymatically modified soybean oil with caprylic acid versus physical mixture analogue in obese Zucker rats. | 2000 | J. Agric. Food Chem. | pmid:11087541 |
Mu H and Høy CE | Application of atmospheric pressure chemical ionization liquid chromatography-mass spectrometry in identification of lymph triacylglycerols. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:11087085 |
Schwarzmann G et al. | Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. | 2000 | Meth. Enzymol. | pmid:11070901 |
Awan MM et al. | Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart. | 2000 | Mol. Cell. Biochem. | pmid:11055554 |
Kim JY et al. | Lipid oxidation is reduced in obese human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052958 |
Lee JS et al. | Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. | 2000 | Am. J. Gastroenterol. | pmid:11051344 |
Panchal AR et al. | Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11045976 |
Wu P et al. | Effects of lipid-related factors on adipocyte differentiation of bovine stromal-vascular cells in primary culture. | 2000 | J. Vet. Med. Sci. | pmid:11039587 |
Berne C | The effect of fatty acids and ketone bodies on the biosynthesis of insulin in isolated pancreatic islets of obese hyperglycemic mice. | 1975 | Horm. Metab. Res. | pmid:1102408 |
Lagrange F et al. | Binding of ketoprofen enantiomers in various human albumin preparations. | 2000 | J Pharm Biomed Anal | pmid:11022905 |
Symonds EL et al. | Assessment of gastric emptying in the mouse using the [13C]-octanoic acid breath test. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10972530 |
Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
Sueyasu M et al. | Protein binding and the metabolism of thiamylal enantiomers in vitro. | 2000 | Anesth. Analg. | pmid:10960410 |
Barron JT et al. | Effect of serum albumin on vascular smooth muscle metabolism. | 2000 | Biochim. Biophys. Acta | pmid:10924897 |
Durner R et al. | Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates. | 2000 | Appl. Environ. Microbiol. | pmid:10919799 |
Peachey SE et al. | Gastrointestinal transit times in young and old cats. | 2000 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10908855 |
Montessuit C et al. | Postischemic recovery of heart metabolism and function: role of mitochondrial fatty acid transfer. | 2000 | J. Appl. Physiol. | pmid:10904042 |
Grill V and Qvigstad E | Fatty acids and insulin secretion. | 2000 | Br. J. Nutr. | pmid:10889796 |
Dirusso CC et al. | Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains. | 2000 | Eur. J. Biochem. | pmid:10880966 |
Guo W et al. | Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate. | 2000 | Biochem. J. | pmid:10880345 |
Arakawa T and Kita Y | Stabilizing effects of caprylate and acetyltryptophanate on heat-induced aggregation of bovine serum albumin. | 2000 | Biochim. Biophys. Acta | pmid:10862953 |
Hong K et al. | Effect of C:N molar ratio on monomer composition of polyhydroxyalkanoates produced by Pseudomonas mendocina 0806 and Pseudomonas pseudoalkaligenus YS1. | 2000 | Appl. Biochem. Biotechnol. | pmid:10849851 |
Gonze MD et al. | Orally administered unfractionated heparin with carrier agent is therapeutic for deep venous thrombosis. | 2000 | Circulation | pmid:10840020 |
Piette V et al. | Non-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions. | 2000 | J Chromatogr A | pmid:10839155 |
Ishii-Iwamoto EL et al. | Effects of norepinephrine on the metabolism of fatty acids with different chain lengths in the perfused rat liver. | 2000 | Mol. Cell. Biochem. | pmid:10821418 |
Watanabe K et al. | Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity. | 2000 | J. Biol. Chem. | pmid:10801788 |
Vincent G et al. | Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10780941 |
Kuge Y et al. | Preliminary evaluation of [1-11C]octanoate as a PET tracer for studying cerebral ischemia: a PET study in rat and canine models of focal cerebral ischemia. | 2000 | Ann Nucl Med | pmid:10770584 |
Cabrera-Crespo J et al. | Albumin purification from human placenta. | 2000 | Biotechnol. Appl. Biochem. | pmid:10744954 |
Lemieux G et al. | Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. | 1976 | Am. J. Physiol. | pmid:10736 |
Baeyens WR et al. | Application of the restricted-access precolumn packing material alkyl-diol silica in a column-switching system for the determination of ketoprofen enantiomers in horse plasma. | 2000 | J Chromatogr A | pmid:10735295 |
Boullanger P et al. | Syntheses of amphiphilic glycosylamides from glycosyl azides without transient reduction to glycosylamines. | 2000 | Carbohydr. Res. | pmid:10702876 |
Hacking MA et al. | Lipase and esterase-catalyzed acylation of hetero-substituted nitrogen nucleophiles in water and organic solvents. | 2000 | Biotechnol. Bioeng. | pmid:10699875 |
Hajjaj H et al. | Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus ruber. | 2000 | Appl. Environ. Microbiol. | pmid:10698780 |
Tian W et al. | Production of polyesters consisting of medium chain length 3-hydroxyalkanoic acids by Pseudomonas mendocina 0806 from various carbon sources. | 2000 | Antonie Van Leeuwenhoek | pmid:10696875 |
Mu H and Høy CE | Effects of different medium-chain fatty acids on intestinal absorption of structured triacylglycerols. | 2000 | Lipids | pmid:10695928 |
Gandhi NN and Mukherjee KD | Specificity of papaya lipase in esterification with respect to the chemical structure of substrates. | 2000 | J. Agric. Food Chem. | pmid:10691676 |
Traul KA et al. | Review of the toxicologic properties of medium-chain triglycerides. | 2000 | Food Chem. Toxicol. | pmid:10685018 |
Shen JJ et al. | Acylcarnitines in fibroblasts of patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and other fatty acid oxidation disorders. | 2000 | J. Inherit. Metab. Dis. | pmid:10682306 |
Iwahashi H | Some polyphenols inhibit the formation of pentyl radical and octanoic acid radical in the reaction mixture of linoleic acid hydroperoxide with ferrous ions. | 2000 | Biochem. J. | pmid:10677343 |
Debreceni A et al. | Capsaicin increases gastric emptying rate in healthy human subjects measured by 13C-labeled octanoic acid breath test. | 1999 | J. Physiol. Paris | pmid:10674924 |
Kubies D et al. | Microdomain structure in polylactide-block-poly(ethylene oxide) copolymer films. | 2000 | Biomaterials | pmid:10674818 |
Gueguen V et al. | Fatty acid and lipoic acid biosynthesis in higher plant mitochondria. | 2000 | J. Biol. Chem. | pmid:10671542 |
Ziesmann J et al. | Chemicals in laboratory room air stimulate olfactory neurons of female Bombyx mori. | 2000 | Chem. Senses | pmid:10667991 |
Delbende B et al. | 13C-octanoic acid breath test for gastric emptying measurement. | 2000 | Eur J Gastroenterol Hepatol | pmid:10656216 |
Barron JT and Gu L | Energetic effects of adenosine on vascular smooth muscle. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10644580 |
Xu X et al. | Synthesis of structured triacylglycerols by lipase-catalyzed acidolysis in a packed bed bioreactor. | 2000 | J. Agric. Food Chem. | pmid:10637041 |
Flores MV et al. | The nature of fatty acid modifies the equilibrium position in the esterification catalyzed by lipase. | 2000 | Biotechnol. Bioeng. | pmid:10620267 |
Antonio RV et al. | Analysis of in vivo substrate specificity of the PHA synthase from Ralstonia eutropha: formation of novel copolyesters in recombinant Escherichia coli. | 2000 | FEMS Microbiol. Lett. | pmid:10612741 |
Toepfer M et al. | Noninvasive (13)C-octanoic acid breath test shows delayed gastric emptying in patients with amyotrophic lateral sclerosis. | 1999 Nov-Dec | Digestion | pmid:10545728 |
Kemp-Harper R et al. | Sodium ions in ordered environments in biological systems: analysis of 23Na NMR spectra. | 1999 | J. Magn. Reson. | pmid:10497043 |
Robinson MK et al. | A two-center study of the development of acute irritation responses to fatty acids. | 1999 | Am. J. Contact Dermatitis | pmid:10444106 |
González A et al. | [Studying of gastric emptying for solids and liquids by means of using stable isotopes]. | 1998 Apr-Jun | Rev Med Univ Navarra | pmid:10420944 |
González A et al. | [Applications of stable isotopes in biomedical sciences]. | 1998 Apr-Jun | Rev Med Univ Navarra | pmid:10420942 |
Van Den Driessche M et al. | Gastric emptying in formula-fed and breast-fed infants measured with the 13C-octanoic acid breath test. | 1999 | J. Pediatr. Gastroenterol. Nutr. | pmid:10400103 |
Barnett C et al. | Reproducibility of the 13C-octanoic acid breath test for assessment of gastric emptying in healthy preterm infants. | 1999 | J. Pediatr. Gastroenterol. Nutr. | pmid:10400099 |
Zhang GG and Grant DJ | Incorporation mechanism of guest molecules in crystals: solid solution or inclusion? | 1999 | Int J Pharm | pmid:10370203 |
Gao J and Serrero G | Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. | 1999 | J. Biol. Chem. | pmid:10358026 |