octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Grill V and Qvigstad E | Fatty acids and insulin secretion. | 2000 | Br. J. Nutr. | pmid:10889796 |
Montessuit C et al. | Postischemic recovery of heart metabolism and function: role of mitochondrial fatty acid transfer. | 2000 | J. Appl. Physiol. | pmid:10904042 |
Peachey SE et al. | Gastrointestinal transit times in young and old cats. | 2000 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10908855 |
Durner R et al. | Accumulation of Poly[(R)-3-hydroxyalkanoates] in Pseudomonas oleovorans during growth with octanoate in continuous culture at different dilution rates. | 2000 | Appl. Environ. Microbiol. | pmid:10919799 |
Barron JT et al. | Effect of serum albumin on vascular smooth muscle metabolism. | 2000 | Biochim. Biophys. Acta | pmid:10924897 |
Sueyasu M et al. | Protein binding and the metabolism of thiamylal enantiomers in vitro. | 2000 | Anesth. Analg. | pmid:10960410 |
Kuge Y et al. | [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. | 2000 | Biol. Pharm. Bull. | pmid:10963308 |
Symonds EL et al. | Assessment of gastric emptying in the mouse using the [13C]-octanoic acid breath test. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10972530 |
Lagrange F et al. | Binding of ketoprofen enantiomers in various human albumin preparations. | 2000 | J Pharm Biomed Anal | pmid:11022905 |
Berne C | The effect of fatty acids and ketone bodies on the biosynthesis of insulin in isolated pancreatic islets of obese hyperglycemic mice. | 1975 | Horm. Metab. Res. | pmid:1102408 |
Wu P et al. | Effects of lipid-related factors on adipocyte differentiation of bovine stromal-vascular cells in primary culture. | 2000 | J. Vet. Med. Sci. | pmid:11039587 |
Panchal AR et al. | Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11045976 |
Lee JS et al. | Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. | 2000 | Am. J. Gastroenterol. | pmid:11051344 |
Kim JY et al. | Lipid oxidation is reduced in obese human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052958 |
Awan MM et al. | Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart. | 2000 | Mol. Cell. Biochem. | pmid:11055554 |
Schwarzmann G et al. | Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. | 2000 | Meth. Enzymol. | pmid:11070901 |
Mu H and Høy CE | Application of atmospheric pressure chemical ionization liquid chromatography-mass spectrometry in identification of lymph triacylglycerols. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:11087085 |
Lee KT et al. | Nutritional effects of enzymatically modified soybean oil with caprylic acid versus physical mixture analogue in obese Zucker rats. | 2000 | J. Agric. Food Chem. | pmid:11087541 |
Benthem L et al. | Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11093916 |
Cappello G et al. | Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. | 2000 | Am. J. Gastroenterol. | pmid:11095323 |
Piett V et al. | Enantioseparation of anionic analytes by non-aqueous capillary electrophoresis using quinine and quinidine derivatives as chiral counter-ions. | 2000 | J Chromatogr A | pmid:11100848 |
Miller JR et al. | Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein. | 2000 | Biochemistry | pmid:11106496 |
Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
Hoffmann N et al. | Homologous functional expression of cryptic phaG from Pseudomonas oleovorans establishes the transacylase-mediated polyhydroxyalkanoate biosynthetic pathway. | 2000 | Appl. Microbiol. Biotechnol. | pmid:11131392 |
Hosoda H et al. | Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11162448 |
Taylor SI et al. | Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio. | 1975 | J. Biol. Chem. | pmid:1116996 |
Gandhi NN and Mukherjee KD | Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases. | 2000 | Biochem. Soc. Trans. | pmid:11171278 |
Kulik W et al. | Improved use of the [13C]octanoic acid breath test as intra-individual parameter to study the effect of a prokinetic drug on gastric emptying in preterm infants with oral feeding intolerance. | 2001 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:11204215 |
Iwahashi H | High-performance liquid chromatographic determination of linoleic acid peroxide-derived radicals using electrochemical detection. | 2000 | J Chromatogr A | pmid:11204234 |
Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
Plante OJ et al. | Automated solid-phase synthesis of oligosaccharides. | 2001 | Science | pmid:11222853 |
Lu X et al. | [Production, characterization and purification of monoclonal antibodies against antigens of Mycobacterium tuberculosis H37Rv strain]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11225032 |
Sibille B et al. | The mitochondrial consequences of uncoupling intact cells depend on the nature of the exogenous substrate. | 2001 | Biochem. J. | pmid:11256968 |
Staeffen J et al. | [Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis. 150 dosages in 61 patients (author's transl)]. | 1979 | Nouv Presse Med | pmid:112576 |
Wyse CA et al. | Assessment of the rate of solid-phase gastric emptying in ponies by means of the 13C-octanoic acid breath test: a preliminary study. | 2001 | Equine Vet. J. | pmid:11266071 |
Raza S et al. | Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study. | 2001 | Protein Sci. | pmid:11266619 |
Davidson NE et al. | Synthesis, analysis and rearrangement of novel unnatural glucosinolates. | 2001 | Carbohydr. Res. | pmid:11270808 |
Briaud I et al. | Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. | 2001 | Diabetes | pmid:11272142 |
Vessey DA | Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. | 2001 | Dig. Dis. Sci. | pmid:11281196 |
Tangen O et al. | Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. | 1975 | Scand. J. Clin. Lab. Invest. | pmid:1129590 |
Sellappan S and Akoh CC | Synthesis of structured lipids by transesterification of trilinolein catalyzed by Lipozyme IM60. | 2001 | J. Agric. Food Chem. | pmid:11308369 |
Ushigome F et al. | Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). | 2001 | Eur. J. Pharmacol. | pmid:11334847 |
Money SR and York JW | Development of oral heparin therapy for prophylaxis and treatment of deep venous thrombosis. | 2001 | Cardiovasc Surg | pmid:11336843 |
Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
Talley NJ et al. | Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? | 2001 | Am. J. Gastroenterol. | pmid:11374677 |
Sek L et al. | Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis. | 2001 | J Pharm Biomed Anal | pmid:11377046 |
Cabral MG et al. | Mechanisms underlying the acquisition of resistance to octanoic-acid-induced-death following exposure of Saccharomyces cerevisiae to mild stress imposed by octanoic acid or ethanol. | 2001 | Arch. Microbiol. | pmid:11382226 |
Liu X et al. | [One simple and efficient method for purification of IgG McAb from mice ascites: caprylic acid/ammonium sulfate precipitation]. | 1999 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:11387969 |
Karagül-Yüceer Y et al. | Aroma-active components of nonfat dry milk. | 2001 | J. Agric. Food Chem. | pmid:11409991 |
Zhou GW et al. | [Esterification of octanoic acid with 1-octanol catalyzed by lipase in W/O microemulsions and in microemulsion-based organogels]. | 2001 | Sheng Wu Gong Cheng Xue Bao | pmid:11411238 |