octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Severe Acute Respiratory Syndrome D045169 1 associated lipids
Gallstones D042882 3 associated lipids
Essential Tremor D020329 2 associated lipids
REM Sleep Behavior Disorder D020187 1 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Endotoxemia D019446 27 associated lipids
Gastroparesis D018589 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Prion Diseases D017096 2 associated lipids
Liver Failure D017093 5 associated lipids
Critical Illness D016638 13 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
Urinary Incontinence D014549 4 associated lipids
Stomach Diseases D013272 7 associated lipids
Starvation D013217 47 associated lipids
Snake Bites D012909 1 associated lipids
Seizures D012640 87 associated lipids
Schistosomiasis D012552 4 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Parkinson Disease D010300 53 associated lipids
Obesity D009765 29 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Memory Disorders D008569 33 associated lipids
Malocclusion D008310 3 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Kidney Diseases D007674 29 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Hemorrhage D006470 15 associated lipids
Hemolysis D006461 131 associated lipids
Glioma D005910 112 associated lipids
Giardiasis D005873 3 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Flatulence D005414 1 associated lipids
Epilepsy D004827 35 associated lipids
Edema D004487 152 associated lipids
Dyspepsia D004415 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Vinay P et al. Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. 1976 Am. J. Physiol. pmid:970471
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
McDaniel HG Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. 1975 Am. J. Physiol. pmid:1211489
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Patel TB Effect of sulfonylureas on hepatic fatty acid oxidation. 1986 Am. J. Physiol. pmid:3090894
Chacín J et al. Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. 1986 Am. J. Physiol. pmid:3090895
Maes BD et al. Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. 1998 Am. J. Physiol. pmid:9655697
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
Chen TM et al. Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction. 1997 Am. J. Physiol. pmid:9374750
Adams SH and Odle J Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. 1993 Am. J. Physiol. pmid:8238444
Ben Cheikh R et al. Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. 1994 Am. J. Physiol. pmid:8203607
Yox DP and Ritter RC Capsaicin attenuates suppression of sham feeding induced by intestinal nutrients. 1988 Am. J. Physiol. pmid:3140678
Hütter JF et al. Effect of fatty acid oxidation on efficiency of energy production in rat heart. 1985 Am. J. Physiol. pmid:4051011
Azain MJ and Ontko JA An explanation for decreased ketogenesis in the liver of the obese Zucker rat. 1989 Am. J. Physiol. pmid:2552844
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Witters LA and Trasko CS Regulation of hepatic free fatty acid metabolism by glucagon and insulin. 1979 Am. J. Physiol. pmid:157075
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427