octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sibille B et al. | Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes. | 1995 | Eur. J. Biochem. | pmid:7635161 |
Sarel I and Widmaier EP | Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. | 1995 | Am. J. Physiol. | pmid:7611525 |
Grekin RJ et al. | Pressor effects of portal venous oleate infusion. A proposed mechanism for obesity hypertension. | 1995 | Hypertension | pmid:7607723 |
Nagatsugi F et al. | 18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution. | 1995 | Chem. Pharm. Bull. | pmid:7600614 |
Duan LP et al. | Influence of cisapride on gastric emptying of solids and liquids monitored by 13C breath tests. | 1995 | Dig. Dis. Sci. | pmid:7587790 |
Onkenhout W et al. | Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. | 1995 | Clin. Chem. | pmid:7586519 |
Yanai S et al. | Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. | 1995 | Pharm. Res. | pmid:7479548 |
Petcu LG and Plaut GW | NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. | 1980 | Biochem. J. | pmid:7470071 |
Zammit VA | The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. | 1980 | Biochem. J. | pmid:7470052 |
Bartels PD and Sestoft L | Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. | 1980 | Biochim. Biophys. Acta | pmid:7448206 |
Nesher R et al. | Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. | 1980 | Am. J. Physiol. | pmid:7446724 |
Kössler F et al. | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. V. Relations between twitch, tetanus and contracture]. | 1980 | Acta Biol. Med. Ger. | pmid:7445906 |
Hollander D | Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. | 1980 | Am. J. Physiol. | pmid:7435575 |
Waymack PP et al. | Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. | 1980 | J. Biol. Chem. | pmid:7430101 |
Krisans SK et al. | Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. | 1980 | J. Biol. Chem. | pmid:7430088 |
Schenk J et al. | Treatment of choledocholithiasis using the transpapillary perfusion technique. | 1980 | Endoscopy | pmid:7428727 |
Morgenthaler JJ et al. | Fatty acid patterns during plasma fractionation. | 1980 | Vox Sang. | pmid:7415075 |
May ME et al. | Mechanism of the stimulation of branched chain oxoacid oxidation in liver by carnitine. | 1980 | J. Biol. Chem. | pmid:7410370 |
Schenk J et al. | [Irrigation treatment of concrements in the common bile duct with octanoate (Capmul 8210) (author's transl)]. | 1980 | Dtsch. Med. Wochenschr. | pmid:7408673 |
Sugano T et al. | Intracellular redox state and stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused rat liver. | 1980 | J. Biochem. | pmid:7358625 |