octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Gadotti C et al. | Inhibitory effect of combinations of caprylic acid and nisin on Listeria monocytogenes in queso fresco. | 2014 | Food Microbiol. | pmid:24387845 |
Al-Abdulla I et al. | Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. | 2014 | J. Immunol. Methods | pmid:24246428 |
Kajimoto M et al. | Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531815 |
Balaraman E et al. | Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. | 2013 | Nat Chem | pmid:23344447 |
Liu P et al. | Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23435986 |
Zurich MG et al. | Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 | Toxicol In Vitro | pmid:22954530 |
Oiso S et al. | Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. | 2013 | J Biomol Screen | pmid:23704134 |
Auriol S et al. | Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit. | 2013 | Retina (Philadelphia, Pa.) | pmid:22902566 |
Nguyen NQ et al. | Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. | 2013 | Intensive Care Med | pmid:23471513 |
Bauchart-Thevret C et al. | Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). | 2013 | J. Nutr. | pmid:23446960 |
Baskaran SA et al. | Inactivation of Escherichia coli O157:H7 on cattle hides by caprylic acid and β-resorcylic acid. | 2013 | J. Food Prot. | pmid:23433381 |
Haubenberger D et al. | Octanoic acid in alcohol-responsive essential tremor: a randomized controlled study. | 2013 | Neurology | pmid:23408867 |
Tong HF et al. | Caprylate as the albumin-selective modifier to improve IgG purification with hydrophobic charge-induction chromatography. | 2013 | J Chromatogr A | pmid:23473512 |
Lim CH et al. | Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. | 2013 | World J. Gastroenterol. | pmid:23885150 |
Eder M et al. | Pharmacokinetic properties of peptidic radiopharmaceuticals: reduced uptake of (EH)3-conjugates in important organs. | 2013 | J. Nucl. Med. | pmid:23804326 |
Frauches TS et al. | Bothropic antivenom based on monoclonal antibodies, is it possible? | 2013 | Toxicon | pmid:23732123 |
Leonard PH et al. | Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid. | 2013 | Fertil. Steril. | pmid:23602317 |
Coenen MJ et al. | Polymorphism in porphyrin monolayers: the relation between adsorption configuration and molecular conformation. | 2013 | Phys Chem Chem Phys | pmid:23620134 |
Bernardino K and de Moura AF | Aggregation thermodynamics of sodium octanoate micelles studied by means of molecular dynamics simulations. | 2013 | J Phys Chem B | pmid:23697593 |
Roda A et al. | Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project. | 2013 | World J. Gastroenterol. | pmid:23599647 |
Morrill KM et al. | Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. | 2013 | J. Dairy Sci. | pmid:23664346 |
Fonseca CR et al. | Storage of refrigerated raw goat milk affecting the quality of whole milk powder. | 2013 | J. Dairy Sci. | pmid:23664351 |
Costello PJ et al. | Synthesis of fruity ethyl esters by acyl coenzyme A: alcohol acyltransferase and reverse esterase activities in Oenococcus oeni and Lactobacillus plantarum. | 2013 | J. Appl. Microbiol. | pmid:23216623 |
Brun AC et al. | Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. | 2013 | Clin Nutr | pmid:23196118 |
Midelfort KS et al. | Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. | 2013 | Protein Eng. Des. Sel. | pmid:23012440 |
Bruno G et al. | 13C-octanoic acid breath test to study gastric emptying time. | 2013 | Eur Rev Med Pharmacol Sci | pmid:24443070 |
Librán-Pérez M et al. | Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23010243 |
Librán-Pérez M et al. | Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. | 2013 | PLoS ONE | pmid:23533628 |
Librán-Pérez M et al. | In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23542747 |
Creedon CT et al. | Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. | 2013 | J Vis Exp | pmid:23542813 |
Alva-Murillo N et al. | Effects of sodium octanoate on innate immune response of mammary epithelial cells during Staphylococcus aureus internalization. | 2013 | Biomed Res Int | pmid:23509807 |
Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
Corona-Castañeda B et al. | Modulators of antibiotic activity from Ipomoea murucoides. | 2013 | Phytochemistry | pmid:23920226 |
de Oliveira AL et al. | Adrenergic metabolic and hemodynamic effects of octopamine in the liver. | 2013 | Int J Mol Sci | pmid:24196353 |
Choi MJ et al. | New decontamination method based on caprylic acid in combination with citric acid or vanillin for eliminating Cronobacter sakazakii and Salmonella enterica serovar Typhimurium in reconstituted infant formula. | 2013 | Int. J. Food Microbiol. | pmid:24042002 |
Scott G et al. | Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. | 2013 | Langmuir | pmid:24144273 |
Suzuki S et al. | Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23376076 |
Hulankova R et al. | Combined antimicrobial effect of oregano essential oil and caprylic acid in minced beef. | 2013 | Meat Sci. | pmid:23743028 |
Guo H et al. | Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24018188 |
Harmancey R et al. | Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. | 2013 | FASEB J. | pmid:23825227 |
Shilling M et al. | Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. | 2013 | J Med Food | pmid:24328700 |
Hungate EA et al. | A locus in Drosophila sechellia affecting tolerance of a host plant toxin. | 2013 | Genetics | pmid:24037270 |
Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
Zimmermann S et al. | Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. | 2012 Jan-Mar | Sci Pharm | pmid:22396915 |
Morais V and Massaldi H | A model mechanism for protein precipitation by caprylic acid: application to plasma purification. | 2012 Jan-Feb | Biotechnol. Appl. Biochem. | pmid:22332745 |
Ariyasu H et al. | Transgenic mice overexpressing ghrelin or ghrelin analog. | 2012 | Meth. Enzymol. | pmid:22975065 |
Kaiya H et al. | Determination of nonmammalian ghrelin. | 2012 | Meth. Enzymol. | pmid:22975047 |
Kojima M et al. | Purification of rat and human ghrelins. | 2012 | Meth. Enzymol. | pmid:22975045 |
Ryu JK and Yoo SD | Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. | 2012 | Drug Dev Ind Pharm | pmid:22283588 |
Maricic MJ | Oral calcitonin. | 2012 | Curr Osteoporos Rep | pmid:22281725 |
Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
Cordes AA et al. | Selective domain stabilization as a strategy to reduce fusion protein aggregation. | 2012 | J Pharm Sci | pmid:22234888 |
Escapa IF et al. | The polyhydroxyalkanoate metabolism controls carbon and energy spillage in Pseudomonas putida. | 2012 | Environ. Microbiol. | pmid:22225632 |
Wang CH et al. | Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. | 2012 | Biomacromolecules | pmid:22145634 |
Allam G et al. | Evaluation of a 14.5 kDa-Fasciola gigantica fatty acid binding protein as a diagnostic antigen for human fascioliasis. | 2012 | Parasitol. Res. | pmid:22113304 |
Henderson EA and Donaldson DJ | Influence of organic coatings on pyrene ozonolysis at the air-aqueous interface. | 2012 | J Phys Chem A | pmid:22107352 |
Hoffman I and Tack J | Assessment of gastric motor function in childhood functional dyspepsia and obesity. | 2012 | Neurogastroenterol. Motil. | pmid:22103293 |
Calandra P et al. | Self-assembly in surfactant-based liquid mixtures: octanoic acid/Bis(2-ethylhexyl)amine systems. | 2012 | J Colloid Interface Sci | pmid:22041199 |
Can Güven S and Laska M | Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. | 2012 | PLoS ONE | pmid:22479594 |
Brault G et al. | Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2). | 2012 | PLoS ONE | pmid:22396747 |
Pereira RF et al. | Effect of metal ion hydration on the interaction between sodium carboxylates and aluminum(III) or chromium(III) ions in aqueous solution. | 2012 | Langmuir | pmid:22107111 |
Hossain MA et al. | Effect of vehicle systems, pH and enhancers on the permeation of highly lipophilic aripiprazole from Carbopol 971P gel systems across human cadaver skin. | 2012 | Drug Dev Ind Pharm | pmid:22067044 |
Poblete-Castro I et al. | The metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single- and multiple-nutrient-limited growth: highlights from a multi-level omics approach. | 2012 | Microb. Cell Fact. | pmid:22433058 |
Mukabana WR et al. | A novel synthetic odorant blend for trapping of malaria and other African mosquito species. | 2012 | J. Chem. Ecol. | pmid:22426893 |
Gschwind HP et al. | Metabolism and disposition of the oral absorption enhancer 14C-radiolabeled 8-(N-2-hydroxy-5-chlorobenzoyl)-amino-caprylic acid (5-CNAC) in healthy postmenopausal women and supplementary investigations in vitro. | 2012 | Eur J Pharm Sci | pmid:22579664 |
Ferreira BS et al. | A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils. | 2012 | ScientificWorldJournal | pmid:22593692 |
Brodsky Y et al. | Caprylic acid precipitation method for impurity reduction: an alternative to conventional chromatography for monoclonal antibody purification. | 2012 | Biotechnol. Bioeng. | pmid:22549395 |
Tsukamoto A et al. | Effect of mosapride on prednisolone-induced gastric mucosal injury and gastric-emptying disorder in dog. | 2012 | J. Vet. Med. Sci. | pmid:22531101 |
Scaini G et al. | Toxicity of octanoate and decanoate in rat peripheral tissues: evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle. | 2012 | Mol. Cell. Biochem. | pmid:22015654 |
Kuo CH et al. | High yield of wax ester synthesized from cetyl alcohol and octanoic acid by lipozyme RMIM and Novozym 435. | 2012 | Int J Mol Sci | pmid:23109878 |
Gumel AM et al. | Biosynthesis and characterization of polyhydroxyalkanoates copolymers produced by Pseudomonas putida Bet001 isolated from palm oil mill effluent. | 2012 | PLoS ONE | pmid:23028854 |
Librán-Pérez M et al. | Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22496361 |
Zhang JH et al. | High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction. | 2012 | Enzyme Microb. Technol. | pmid:22500900 |
Nahab FB et al. | Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. | 2012 | Neurotherapeutics | pmid:22454323 |
Ogawa N et al. | Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. | 2012 | Metab. Clin. Exp. | pmid:22445513 |
Tetrick MA et al. | Octanoate and nonaoate oxidation increases 50-80% over the first two days of life in piglet triceps brachii and gracilis muscle strips. | 2012 | J. Nutr. | pmid:22513984 |
Kollanoor-Johny A et al. | Caprylic acid reduces Salmonella Enteritidis populations in various segments of digestive tract and internal organs of 3- and 6-week-old broiler chickens, therapeutically. | 2012 | Poult. Sci. | pmid:22700516 |
Simsiriwong P et al. | A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). | 2012 | Biologicals | pmid:22704919 |
Yamamoto Y et al. | Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis. | 2012 | Am. J. Clin. Nutr. | pmid:22648712 |
Zentek J et al. | Intestinal concentrations of free and encapsulated dietary medium-chain fatty acids and effects on gastric microbial ecology and bacterial metabolic products in the digestive tract of piglets. | 2012 | Arch Anim Nutr | pmid:22397093 |
Bu W et al. | Ferritin couples iron and fatty acid metabolism. | 2012 | FASEB J. | pmid:22362897 |
Eursakun S et al. | Studies on the fractionation of equine antivenom IgG by combinations of ammonium sulfate and caprylic acid. | 2012 | Toxicon | pmid:22842065 |
Li RL et al. | Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids. | 2012 | J. Biol. Chem. | pmid:22474325 |
Nejati K and Zabihi R | Preparation and magnetic properties of nano size nickel ferrite particles using hydrothermal method. | 2012 | Chem Cent J | pmid:22462726 |
Lee S et al. | Ghrelin protects spinal cord motoneurons against chronic glutamate excitotoxicity by inhibiting microglial activation. | 2012 | Korean J. Physiol. Pharmacol. | pmid:22416219 |
De Silva A and Bloom SR | Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity. | 2012 | Gut Liver | pmid:22375166 |
Kim H et al. | Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. | 2012 | Ann Dermatol | pmid:22363147 |
Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
Nóbrega AC et al. | Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. | 2012 | BMC Gastroenterol | pmid:23216812 |
Takatani-Nakase T et al. | Transcutaneous immunization system using a hydrotropic formulation induces a potent antigen-specific antibody response. | 2012 | PLoS ONE | pmid:23110149 |
Ishida T et al. | Base-free direct oxidation of 1-octanol to octanoic acid and its octyl ester over supported gold catalysts. | 2012 | ChemSusChem | pmid:23065901 |
Liu Z et al. | Purification of human immunoglobulins A, G and M from Cohn fraction II/III by small peptide affinity chromatography. | 2012 | J Chromatogr A | pmid:23026261 |
Kim J et al. | A pronounced dispersion effect of crystalline silicon nanoparticles on the performance and stability of polymer:fullerene solar cells. | 2012 | ACS Appl Mater Interfaces | pmid:23027775 |
Focsan AL et al. | EPR study of the astaxanthin n-octanoic acid monoester and diester radicals on silica-alumina. | 2012 | J Phys Chem B | pmid:23039790 |
Bando M et al. | Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22114024 |
Fan X et al. | Identification and characterization of a novel thermostable pyrethroid-hydrolyzing enzyme isolated through metagenomic approach. | 2012 | Microb. Cell Fact. | pmid:22409882 |
Chang P et al. | The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. | 2012 | Dis Model Mech | pmid:21876211 |
Prajapati HN et al. | A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. | 2012 | Pharm. Res. | pmid:21861203 |
Mohan A et al. | Role of peroxyacetic acid, octanoic acid, malic acid, and potassium lactate on the microbiological and instrumental color characteristics of ground beef. | 2012 | J. Food Sci. | pmid:22352902 |
Moschonas G et al. | Activity of caprylic acid, carvacrol, ε-polylysine and their combinations against Salmonella in not-ready-to-eat surface-browned, frozen, breaded chicken products. | 2012 | J. Food Sci. | pmid:22670620 |