octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Anzai N et al. | Molecular mechanism of ochratoxin a transport in the kidney. | 2010 | Toxins (Basel) | pmid:22069643 |
Nudel BC et al. | Optimization by factorial analysis of caprylic acid precipitation of non-immunoglobulins from hyperimmune equine plasma for antivenom preparation. | 2012 | Toxicon | pmid:22079738 |
dos Santos MC et al. | Purification of F(ab')2 anti-snake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purity and yield. | 1989 | Toxicon | pmid:2728022 |
León G et al. | Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols. | 2005 | Toxicon | pmid:15581691 |
Herrera M et al. | Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs. | 2005 | Toxicon | pmid:16183094 |
Rojas G et al. | Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. | 1994 | Toxicon | pmid:8016856 |
Otero-Patiño R et al. | Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. | 2012 | Toxicon | pmid:22146491 |
Otero R et al. | A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms. | 1999 | Toxicon | pmid:10340829 |
Eursakun S et al. | Studies on the fractionation of equine antivenom IgG by combinations of ammonium sulfate and caprylic acid. | 2012 | Toxicon | pmid:22842065 |
Frauches TS et al. | Bothropic antivenom based on monoclonal antibodies, is it possible? | 2013 | Toxicon | pmid:23732123 |
Segura A et al. | Stability of equine IgG antivenoms obtained by caprylic acid precipitation: towards a liquid formulation stable at tropical room temperature. | 2009 | Toxicon | pmid:19673074 |
Fernández GP et al. | Neutralization of Bothrops mattogrossensis snake venom from Bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. | 2010 Feb-Mar | Toxicon | pmid:19647761 |
Theakston RD et al. | Report of a WHO workshop on the standardization and control of antivenoms. | 2003 | Toxicon | pmid:12676433 |
Vanden Heuvel JP et al. | Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. | 2006 | Toxicol. Sci. | pmid:16731579 |
Kiang TK et al. | Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21397622 |
Bojes HK and Thurman RG | Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8887448 |
Hernández-Esquivel L et al. | Cardiotoxicity of copper-based antineoplastic drugs casiopeinas is related to inhibition of energy metabolism. | 2006 | Toxicol. Appl. Pharmacol. | pmid:16051288 |
Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
Nau H et al. | Pharmacokinetic aspects of drug effects in vitro (II) placental transfer to the embryo and activity of some carboxylic acids structurally related to valproic acid in whole embryos in culture. | 1988 | Toxicol In Vitro | pmid:20702331 |
Zurich MG et al. | Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 | Toxicol In Vitro | pmid:22954530 |