octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Crohn Disease D003424 12 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Starvation D013217 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Trauner DA and Huttenlocher PR Short chain fatty acid-induced central hyperventilation in rabbits. 1978 Neurology pmid:567765
Demol P and Sarles H Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. 1978 J. Physiol. (Lond.) pmid:633115
Hansford RG Lipid oxidation by heart mitochondria from young adult and senescent rats. 1978 Biochem. J. pmid:637843
Meisner H and Neet K Competitive binding of long-chain free fatty acids, octanoate, and chlorophenoxyisobutyrate to albumin. 1978 Mol. Pharmacol. pmid:642932
Mannaerts GP et al. Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment. 1978 Biochim. Biophys. Acta pmid:656451
Scholz R et al. The effect of fatty acids on the regulation of pyruvate dehydrogenase in perfused rat liver. 1978 Eur. J. Biochem. pmid:658055
Rabinowitz JL et al. Sources of serum [14C]-octanoate in cirrhosis of the liver and hepatic encephalopathy. 1978 J. Lab. Clin. Med. pmid:621424
Kinnula VL and Hassinen I Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart. 1978 Acta Physiol. Scand. pmid:626089
Fildes FJ and Oliver JE Interaction of cortisol-21-palmitate with liposomes examined by differential scanning calorimetry. 1978 J. Pharm. Pharmacol. pmid:26761
Sheikh MI et al. On the mechanism of p-piperidyl and p-benzyl sulfamyl benzoic acids transport by renal tissue. 1978 Arch. Int. Physiol. Biochim. pmid:87158
Rabinowitz JL et al. The effects of intravenous sodium octanoate on the rhesus monkey. 1978 Am. J. Gastroenterol. pmid:96693
Valdivia MM et al. [Effect of octanoic acid on the insulin secretion in response to glucose in vitro (author's transl)]. 1979 Rev. Esp. Fisiol. pmid:504776
Avenard G et al. [The prevention of chickenpox in high risk children. Comparison of the effectiveness of specific immunoglobulins and of defibrinated convalescent plasma. 414 cases (author's transl)]. 1979 Nouv Presse Med pmid:221885
Salesse R and Garnier J Effects of drugs on pigeon erythrocyte membrane and asymmetric control or adenylate cyclase by the lipid bilayer. 1979 Biochim. Biophys. Acta pmid:222319
Strong P et al. Aerobic lactate synthesis by cardiac muscle. 1979 Eur. J. Biochem. pmid:230966
Brady LJ et al. Gluconeogenesis in isolated chicken (Gallus domesticus) liver cells. 1979 Comp. Biochem. Physiol., B pmid:318406
Witters LA and Trasko CS Regulation of hepatic free fatty acid metabolism by glucagon and insulin. 1979 Am. J. Physiol. pmid:157075
Ring J et al. Anaphylactoid reactions to infusions of plasma protein and human serum albumin. Role of aggregated proteins and of stabilizers added during production. 1979 Clin. Allergy pmid:421339
Dhopeshwarkar GA and Subramanian C Lipogenesis in the developing brain: utilization of radioactive leucine, isoleucine, octanoic acid and beta-hydroxybutyric acid. 1979 Lipids pmid:423709
Trimble ME Transport and metabolism of octanoate by the perfused rat kidney. 1979 Am. J. Physiol. pmid:474762