| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gastroparesis | D018589 | 2 associated lipids |
| Prion Diseases | D017096 | 2 associated lipids |
| Malocclusion | D008310 | 3 associated lipids |
| Giardiasis | D005873 | 3 associated lipids |
| Blind Loop Syndrome | D001765 | 3 associated lipids |
| Coccidiosis | D003048 | 3 associated lipids |
| Gallstones | D042882 | 3 associated lipids |
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Chest Pain | D002637 | 4 associated lipids |
| Intracranial Hypertension | D019586 | 4 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris RA et al. | Regulation of branched-chain alpha-ketoacid dehydrogenase complex by covalent modification. | 1986 | Adv. Enzyme Regul. | pmid:3028049 |
| Jones DB et al. | Hepatic encephalopathy. Application of visual evoked responses to test hypotheses of its pathogenesis in rats. | 1987 | J. Hepatol. | pmid:3033057 |
| Whyte RK et al. | Excretion of dicarboxylic and omega-1 hydroxy fatty acids by low birth weight infants fed with medium-chain triglycerides. | 1986 | Pediatr. Res. | pmid:3080726 |
| Merrill AR et al. | Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. | 1986 | Biochim. Biophys. Acta | pmid:3081028 |
| Veerkamp JH et al. | An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. | 1986 | Biochim. Biophys. Acta | pmid:3081042 |
| Taylor WM et al. | The stimulation of tricarboxylic acid-cycle flux by alpha-adrenergic agonists in perfused rat liver. | 1986 | Biochem. J. | pmid:3082324 |
| Nau H and Löscher W | Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice. | 1986 | Fundam Appl Toxicol | pmid:3086174 |
| Patel TB | Effect of sulfonylureas on hepatic fatty acid oxidation. | 1986 | Am. J. Physiol. | pmid:3090894 |
| ChacÃn J et al. | Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. | 1986 | Am. J. Physiol. | pmid:3090895 |
| Webb T | Identification of interference affecting the gas-liquid chromatography analysis of valproic acid in quality control material. | 1986 | Pathology | pmid:3097616 |
| Forsey RG et al. | Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart. | 1987 | Can. J. Physiol. Pharmacol. | pmid:3107785 |
| King MJ | Hemagglutination enhancement by bovine serum albumin is affected by octanoate, Reactive Blue 2 (Cibacron Blue), and polymer. | 1987 Jul-Aug | Transfusion | pmid:3111035 |
| Swartzentruber MS and Harris RA | Inhibition of metabolic processes by coenzyme-A-sequestering aromatic acids. Prevention by para-chloro- and para-nitrobenzoic acids. | 1987 | Biochem. Pharmacol. | pmid:3117062 |
| Draye JP and Vamecq J | The inhibition by valproic acid of the mitochondrial oxidation of monocarboxylic and omega-hydroxymonocarboxylic acids: possible implications for the metabolism of gamma-aminobutyric acid. | 1987 | J. Biochem. | pmid:3117781 |
| Bellringer ME et al. | Sodium valproate inhibits the movement of secretory vesicles in rat hepatocytes. | 1988 | Biochem. J. | pmid:3124828 |
| Crozier GL | Medium-chain triglyceride feeding over the long term: the metabolic fate of [14C]octanoate and [14C]oleate in isolated rat hepatocytes. | 1988 | J. Nutr. | pmid:3127554 |
| Böhles H et al. | The influence of i.v. MCT and carnitine on the excretion of dicarboxylic acids. | 1988 | Beitr Infusionther Klin Ernahr | pmid:3132147 |
| Vidal H et al. | Inhibition of glucose oxidation by vasoactive intestinal peptide in isolated rat enterocytes. | 1988 | J. Biol. Chem. | pmid:3132456 |
| Yox DP and Ritter RC | Capsaicin attenuates suppression of sham feeding induced by intestinal nutrients. | 1988 | Am. J. Physiol. | pmid:3140678 |
| Arimoto K et al. | Abnormal 13C-fatty acid breath tests in patients treated with valproic acid. | 1988 | J. Child Neurol. | pmid:3143757 |
| Shrake A and Ross PD | Biphasic denaturation of human albumin due to ligand redistribution during unfolding. | 1988 | J. Biol. Chem. | pmid:3170588 |
| Dorset DL | Co-solubility of saturated cholesteryl esters: a comparison of calculated and experimental binary phase diagrams. | 1988 | Biochim. Biophys. Acta | pmid:3179332 |
| Tonsgard JH et al. | Binding of straight-chain saturated dicarboxylic acids to albumin. | 1988 | J. Clin. Invest. | pmid:3183053 |
| Brady LJ et al. | Gluconeogenesis in isolated chicken (Gallus domesticus) liver cells. | 1979 | Comp. Biochem. Physiol., B | pmid:318406 |
| Ruidera E et al. | Fatty acid metabolism in renal ischemia. | 1988 | Lipids | pmid:3185124 |
| Kalbag SS and Palekar AG | Sodium benzoate inhibits fatty acid oxidation in rat liver: effect on ammonia levels. | 1988 | Biochem. Med. Metab. Biol. | pmid:3190922 |
| González-Manchón C et al. | Control of gluconeogenesis: role of fatty acids in the alpha-adrenergic response. | 1988 | Biochim. Biophys. Acta | pmid:3191164 |
| Temponi M et al. | Immunoreactivity and affinity of murine IgG monoclonal antibodies purified by caprylic acid precipitation. | 1988 | J. Immunol. Methods | pmid:3192945 |
| Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
| Butler SM et al. | Fatty acid metabolism of the perfused caudate lobe from livers of fed and fasted non-pregnant and fasted late pregnant ewes. | 1988 | Comp. Biochem. Physiol., B | pmid:3197392 |
| Temiralieva GA et al. | [Prospects for the use of monoclonal antibodies in Yersinia pestis]. | 1988 | Antibiot. Khimioter. | pmid:3218993 |
| Shabalina LP and Spiridonova VS | Toxicity and character of the effect of some zinc compounds. | 1988 | J Hyg Epidemiol Microbiol Immunol | pmid:3221090 |
| Tosh D et al. | Glucagon regulation of gluconeogenesis and ketogenesis in periportal and perivenous rat hepatocytes. Heterogeneity of hormone action and of the mitochondrial redox state. | 1988 | Biochem. J. | pmid:3223900 |
| Trusk TC and Stein EA | Effect of heroin-conditioned auditory stimuli on cerebral functional activity in rats. | 1988 | Pharmacol. Biochem. Behav. | pmid:3227045 |
| Dengler T et al. | Quantitative determination of sodium-octanoate in human serum albumin preparations. | 1988 | Infusionstherapie | pmid:3235205 |
| Lemmen C et al. | Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. | 1988 | Biol. Chem. Hoppe-Seyler | pmid:3242549 |
| Tomita M et al. | Enhancement of colonic drug absorption by the paracellular permeation route. | 1988 | Pharm. Res. | pmid:3244645 |
| Tomita M et al. | Enhancement of colonic drug absorption by the transcellular permeation route. | 1988 | Pharm. Res. | pmid:3247289 |
| Heaney-Kieras J and King TP | Limited pepsin digestion of human plasma albumin. | 1977 | J. Biol. Chem. | pmid:325004 |
| Mortimore GE et al. | Modulation of the amino acid control of hepatic protein degradation by caloric deprivation. Two modes of alanine co-regulation. | 1988 | J. Biol. Chem. | pmid:3264284 |
| Stafford CT et al. | Anaphylaxis to human serum albumin. | 1988 | Ann Allergy | pmid:3274040 |
| Norenberg MD | The role of astrocytes in hepatic encephalopathy. | 1987 Feb-Apr | Neurochem Pathol | pmid:3306480 |
| Mishima M et al. | Studies on the promoting effects of medium chain fatty acid salts on the nasal absorption of insulin in rats. | 1987 | J. Pharmacobio-dyn. | pmid:3328778 |
| Lysiak W et al. | Quantitation of the effect of L-carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria. | 1988 | J. Biol. Chem. | pmid:3335535 |
| Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
| Inoue T et al. | Effect of sodium octanoate and sodium perfluorooctanoate on gel-to-liquid-crystalline phase transition of dipalmitoylphosphatidylcholine vesicle membrane. | 1988 | Chem. Phys. Lipids | pmid:3338099 |
| Trusk TC and Stein EA | Effects of heroin and cocaine on brain activity in rats using [1-14C]octanoate as a fast functional tracer. | 1988 | Brain Res. | pmid:3345450 |
| Rücker W et al. | Antiatherosclerotic and antihyperlipidemic effects of octimibate sodium in rabbits. | 1988 | Atherosclerosis | pmid:3348838 |
| Duran M et al. | Cis-4-decenoic acid in plasma: a characteristic metabolite in medium-chain acyl-CoA dehydrogenase deficiency. | 1988 | Clin. Chem. | pmid:3349606 |
| Tuman RW et al. | Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid (TDGA) on glucose and fatty acid oxidation in isolated rat soleus muscle. | 1988 | Int. J. Biochem. | pmid:3350201 |
| Yoshida Y et al. | Effect of salicylic acid on mitochondrial-peroxisomal fatty acid catabolism. | 1988 | Pediatr. Res. | pmid:3353181 |
| Olubadewo JO et al. | Effects of 8-N,N-diethylamino-octyl-3,4,5-trimethoxybenzoate (TMB-8) HCl and verapamil on the metabolism of free fatty acid by hepatocytes. | 1988 | Biochem. Pharmacol. | pmid:3358779 |
| Wu G and Thompson JR | Effect of pyruvate, octanoate and glucose on leucine degradation in skeletal muscle from fed and fasted chicks. | 1988 | Int. J. Biochem. | pmid:3371527 |
| Zieve L et al. | Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat. | 1988 | J. Lab. Clin. Med. | pmid:3373115 |
| Fellenberg AJ and Pollard AC | A rapid and sensitive gas-liquid chromatographic procedure for the micro determination of sodium valproate (sodium di-N-propylacetate) in plasma or serum. | 1977 | Clin. Chim. Acta | pmid:338203 |
| Matsuzaki K et al. | Inhibition of cortical collecting tubule chloride transport by organic acids. | 1988 | J. Clin. Invest. | pmid:3392216 |
| Ogden JR and Leung K | Purification of murine monoclonal antibodies by caprylic acid. | 1988 | J. Immunol. Methods | pmid:3397551 |
| Allison F et al. | The oxidation of octanoic acid by cultured amniotic fluid cells: the effect of cell type and passage number. | 1988 | Prenat. Diagn. | pmid:3405975 |
| Malewiak MI et al. | Oleate metabolism and endogenous triacylglycerol hydrolysis in isolated hepatocytes from rats fed a high-fat diet. | 1988 May-Jun | Diabete Metab | pmid:3410152 |
| Kajii H et al. | Fluorescence study of the membrane-perturbing action of sodium caprylate as related to promotion of drug absorption. | 1988 | J Pharm Sci | pmid:3411458 |
| Foxworthy PS and Eacho PI | Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone. | 1988 | Biochem. J. | pmid:3415664 |
| Handler JA and Thurman RG | Catalase-dependent ethanol oxidation in perfused rat liver. Requirement for fatty-acid-stimulated H2O2 production by peroxisomes. | 1988 | Eur. J. Biochem. | pmid:3416882 |
| Jenkins DL and Griffith OW | Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3455765 |
| Watford M et al. | The regulation of glutamine and ketone-body metabolism in the small intestine of the long-term (40-day) streptozotocin-diabetic rat. | 1987 | Biochem. J. | pmid:3473986 |
| Trauner DA and Adams HR | Effects of therapeutic agents in a rabbit model of Reye syndrome. | 1987 May-Jun | Pediatr. Neurol. | pmid:3508061 |
| Rösen P et al. | Myocardial performance and metabolism in non-ketotic, diabetic rat hearts: myocardial function and metabolism in vivo and in the isolated perfused heart under the influence of insulin and octanoate. | 1986 Nov-Dec | Basic Res. Cardiol. | pmid:3545178 |
| Thomson AB | The level of dietary protein and carbohydrate has a different effect on intestinal uptake of hexoses and lipids in rabbits with an ileal resection than in those with an intact intestinal tract. | 1987 | Can. J. Physiol. Pharmacol. | pmid:3567736 |
| Bennett MJ et al. | Prenatal diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency. | 1987 | Prenat. Diagn. | pmid:3575262 |
| Lambin P and Debbia M | [IgG4 levels in polyvalent immunoglobulins and immunoglobulins prepared by precipitation with caprylic acid]. | 1986 Oct-Nov | Rev. Fr. Transfus. Immunohematol. | pmid:3576044 |
| Jandacek RJ et al. | The rapid hydrolysis and efficient absorption of triglycerides with octanoic acid in the 1 and 3 positions and long-chain fatty acid in the 2 position. | 1987 | Am. J. Clin. Nutr. | pmid:3578095 |
| Pahl-Wostl C and Seelig J | Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3593540 |
| Reik LM et al. | A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. | 1987 | J. Immunol. Methods | pmid:3598193 |
| Cistola DP et al. | Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites. | 1987 | J. Biol. Chem. | pmid:3611099 |
| Cistola DP et al. | Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites. | 1987 | J. Biol. Chem. | pmid:3611100 |
| Halestrap AP | The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. | 1987 | Biochem. J. | pmid:3663110 |
| Allen PC | The effect of Eimeria acervulina infection on hearts of young broiler chicks. | 1987 Jul-Sep | Avian Dis. | pmid:3675428 |
| Cole SG et al. | Cholesteryl octanoate breath test. Preliminary studies on a new noninvasive test of human pancreatic exocrine function. | 1987 | Gastroenterology | pmid:3678753 |
| el-Aleem SA and Schulz H | Evaluation of inhibitors of fatty acid oxidation in rat myocytes. | 1987 | Biochem. Pharmacol. | pmid:3689454 |
| Yoshioka M et al. | Malabsorption of long-chain fatty acid in cholera toxin-induced secretory diarrhea. | 1986 | Dig. Dis. Sci. | pmid:3698768 |
| Fatania HR et al. | Modulation of pyruvate dehydrogenase kinase activity in cultured hepatocytes by glucagon and n-octanoate. | 1986 | Biochem. J. | pmid:3707545 |
| Letko G and Halangk W | Effect of improved hydrogen supply on energy state, ureogenesis and gluconeogenesis in isolated hepatocytes. | 1986 | Biomed. Biochim. Acta | pmid:3707550 |
| Okita M et al. | Plasma level of branched chain alpha-amino acids following its alpha-keto acid administration to rats. | 1986 | J. Nutr. Sci. Vitaminol. | pmid:3712111 |
| Matsumura T et al. | O2 uptake in periportal and pericentral regions of liver lobule in perfused liver. | 1986 | Am. J. Physiol. | pmid:3717341 |
| Amendt BA and Rhead WJ | The multiple acyl-coenzyme A dehydrogenation disorders, glutaric aciduria type II and ethylmalonic-adipic aciduria. Mitochondrial fatty acid oxidation, acyl-coenzyme A dehydrogenase, and electron transfer flavoprotein activities in fibroblasts. | 1986 | J. Clin. Invest. | pmid:3722376 |
| Beuers U et al. | Control of ketogenesis in the perfused rat liver by the sympathetic innervation. | 1986 | Eur. J. Biochem. | pmid:3732268 |
| Spector R | Development and characterization of pantothenic acid transport in brain. | 1986 | J. Neurochem. | pmid:3734794 |
| Hulshoff A and Roseboom H | Determination of valproic acid (di-N-propyl acetic acid) in plasma by gas-liquid chromatography with pre-column butylation. | 1979 | Clin. Chim. Acta | pmid:373927 |
| Lysiak W et al. | Quantitation of the efflux of acylcarnitines from rat heart, brain, and liver mitochondria. | 1986 | J. Biol. Chem. | pmid:3759988 |
| Higaki K et al. | Effect of medium-chain glycerides (MGK) on the intestinal absorption and the hepatobiliary transport of bromthymol blue. | 1986 | J. Pharmacobio-dyn. | pmid:3761141 |
| Nomura T et al. | Effects of vasopressin, angiotensin II and phenylephrine on hepatic ketogenesis and fatty acid synthesis. | 1986 | Jpn. J. Pharmacol. | pmid:3773344 |
| Garner CW and Behal FJ | Effect of pH on substrate and inhibitor kinetic constants of human liver alanine aminopeptidase. Evidence for two ionizable active center groups. | 1975 | Biochemistry | pmid:38 |
| Clouet P et al. | Study of some factors controlling fatty acid oxidation in liver mitochondria of obese Zucker rats. | 1986 | Biochem. J. | pmid:3800970 |
| McKinney MM and Parkinson A | A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid. | 1987 | J. Immunol. Methods | pmid:3805742 |
| Komura S and Kurahashi K | Biosynthesis of polymyxin E by a cell-free enzyme system. IV. Acylation of enzyme-bound L-2,4-diaminobutyric acid. | 1985 | J. Biochem. | pmid:3861608 |
| Trauner DA and Garrett RS | Effect of octanoate injection on rat blood-brain barrier. | 1985 Jan-Feb | Pediatr. Neurol. | pmid:3880386 |
| Trauner DA and de la Torre JC | Effect of octanoate on blood-brain barrier permeability using L-dopa as a marker. | 1985 Jul-Aug | Pediatr. Neurol. | pmid:3880408 |
| Trice JE and Trauner DA | Alterations in serum glucose and hepatic glycogen concentrations during octanoate administration in rabbits. | 1985 Sep-Oct | Pediatr. Neurol. | pmid:3880415 |
| Beaufrere B et al. | Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. | 1985 | Am. J. Physiol. | pmid:3895976 |
| Schmidt FH et al. | A new inhibitor of the long-chain fatty acid transfer across the mitochondrial membrane: 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1985 | Life Sci. | pmid:3917523 |
| Eanes WF et al. | Targeted selection experiments and enzyme polymorphism: negative evidence for octanoate selection at the G6PD locus in Drosophila melanogaster. | 1985 | Genetics | pmid:3918918 |