octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Essential Tremor D020329 2 associated lipids
Gastroparesis D018589 2 associated lipids
Coccidiosis D003048 3 associated lipids
Giardiasis D005873 3 associated lipids
Malocclusion D008310 3 associated lipids
Gallstones D042882 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Urinary Incontinence D014549 4 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Khabbush A et al. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. 2017 Epilepsia pmid:28682459
Peyser RD et al. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. 2017 Insect Mol. Biol. pmid:28703934
Hsieh CH et al. The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. 2017 Biochemistry pmid:28603981
Kandula M et al. Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. 2016 Int. Immunopharmacol. pmid:27716592
Kateja N et al. Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). 2016 Biotechnol J pmid:27447837
Lemarié F et al. Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. 2016 Biochim. Biophys. Acta pmid:27317984
Sawatani Y et al. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. 2016 Bioorg. Med. Chem. pmid:27301681
Kubota K et al. The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. 2016 Eur J Pharm Sci pmid:26965004
Nakajima K et al. Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 Biomed. Res. pmid:28003581
Hogan S et al. Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. 2016 Antimicrob. Agents Chemother. pmid:27458213
Lockman KA et al. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. 2016 Lipids Health Dis pmid:27368608
Voller B et al. Dose-escalation study of octanoic acid in patients with essential tremor. 2016 J. Clin. Invest. pmid:26927672
Diaz De Rienzo MA et al. Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. 2016 Appl. Microbiol. Biotechnol. pmid:26825819
Nishitani N et al. Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. 2015 Chem Asian J pmid:26033832
Coronado MA et al. Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. 2015 Curr. Protein Pept. Sci. pmid:25961401
Pesce P et al. Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. 2015 J Oral Rehabil pmid:25882620
Kim SA and Rhee MS Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. 2015 Food Microbiol. pmid:25846927
Rodríguez-Moyá M and Gonzalez R Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. 2015 J Proteomics pmid:25845584
Chen Y et al. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. 2015 Int J Pharm pmid:25841571
Oiso S et al. Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. 2015 J Oleo Sci pmid:26521811