octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chickenpox D002644 1 associated lipids
Chronic Disease D002908 7 associated lipids
Chylothorax D002916 1 associated lipids
Coccidiosis D003048 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Crohn Disease D003424 12 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Schadewaldt P et al. Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS). 1997 Clin. Chem. pmid:9068597
Priestman DA et al. Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes. 1997 Biochem. Soc. Trans. pmid:9056999
Viegas CA and Sá-Correia I Effects of low temperatures (9-33 degrees C) and pH (3.3-5.7) in the loss of Saccharomyces cerevisiae viability by combining lethal concentrations of ethanol with octanoic and decanoic acids. 1997 Int. J. Food Microbiol. pmid:9039572
Bikhazi AB et al. Calcium-prostaglandin aggregation and its effect on prostaglandin uptake by isolated rabbit intestine. 1977 J Pharm Sci pmid:903871
Trotter PJ et al. Fatty acid uptake by Caco-2 human intestinal cells. 1996 J. Lipid Res. pmid:9026531
Yamazaki S et al. Uptake of radioactive octanoate in astrocytoma cells: basic studies for application of [11C]octanoate as a PET tracer. 1996 Ann Nucl Med pmid:9006724
Kuge Y et al. [1-11C]octanoate as a potential PET tracer for studying glial functions: PET evaluation in rats and cats. 1996 Nucl. Med. Biol. pmid:9004290
Yang H et al. Enhancing the stereoselectivity and activity of Candida species lipase in organic solvent by noncovalent enzyme modification. 1996 Ann. N. Y. Acad. Sci. pmid:8958099
Sidossis LS et al. Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. 1996 J. Clin. Invest. pmid:8941640
Constantinides PP et al. Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation. 1996 Pharm. Res. pmid:8932438
Guthy E Enteric-coated fish oil in Crohn's disease. 1996 N. Engl. J. Med. pmid:8927072
Katoh K et al. Octanoate increases cytosolic Ca2+ concentration and membrane conductance in ovine pancreatic acinar cells. 1996 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:8923746
Castel MA et al. The antibodies causing thyroid stimulating hormone-binding inhibition (TSH-BI) are not responsible for the specific inhibition of gonadal steroidogenesis by Graves' sera. 1996 J. Reprod. Immunol. pmid:8920164
Kalogeris TJ et al. Intestinal synthesis and lymphatic secretion of apolipoprotein A-IV vary with chain length of intestinally infused fatty acids in rats. 1996 J. Nutr. pmid:8914941
Bojes HK and Thurman RG Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. 1996 Toxicol. Appl. Pharmacol. pmid:8887448
Fulgencio JP et al. Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats. 1996 Diabetes pmid:8866561
Veereman-Wauters G et al. The 13C-octanoic acid breath test: a noninvasive technique to assess gastric emptying in preterm infants. 1996 J. Pediatr. Gastroenterol. Nutr. pmid:8856575
Petschow BW et al. Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. 1996 Antimicrob. Agents Chemother. pmid:8834870
Cave AC et al. A model of anoxic preconditioning in the isolated rat cardiac myocyte. Importance of adenosine and insulin. 1996 May-Jun Basic Res. Cardiol. pmid:8831940
Priestman DA et al. Pyruvate inhibition of pyruvate dehydrogenase kinase. Effects of progressive starvation and hyperthyroidism in vivo, and of dibutyryl cyclic AMP and fatty acids in cultured cardiac myocytes. 1996 FEBS Lett. pmid:8814284