octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chest Pain D002637 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Asthenia D001247 5 associated lipids
Liver Failure D017093 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Chronic Disease D002908 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Campylobacter Infections D002169 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Critical Illness D016638 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Veitch K and Van Hoof F In vitro effects of eight-carbon fatty acids on oxidations in rat liver mitochondria. 1990 Biochem. Pharmacol. pmid:2242043
Marchington DR et al. Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat cardiac myocytes. 1990 Biochem. J. pmid:2158309
Kingsley-Hickman PB et al. 31P NMR measurement of mitochondrial uncoupling in isolated rat hearts. 1990 J. Biol. Chem. pmid:2136855
McNamara BC and Jefcoate CR Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from ACTH-treated rats: differential responses to different reducing precursors. 1990 Mol. Cell. Endocrinol. pmid:2176627
Haufe CC et al. Development and regulation of hepatocellular fatty acid synthesis towards term: studies in isolated fetal rat hepatocytes. 1990 Biomed. Biochim. Acta pmid:2177982
Yamazaki M et al. The effect of fatty acids on the rectal absorption of acyclovir in rats. 1990 J. Pharm. Pharmacol. pmid:1979629
Andres T et al. Brain edema in acute liver failure. Insight from experimental studies. 1990 Rev. Invest. Clin. pmid:19256151
Kim CS et al. L-Carnitine prevents mitochondrial damage induced by octanoic acid in the rat choroid plexus. 1990 Brain Res. pmid:1964833
Ali ST et al. Octanoylation of the lipoyl domains of the pyruvate dehydrogenase complex in a lipoyl-deficient strain of Escherichia coli. 1990 Mol. Microbiol. pmid:2215217
Renier G et al. Cellular mechanism of caprylic acid-induced growth hormone suppression. 1990 Metab. Clin. Exp. pmid:2170821
Rozas I et al. Effects of acute valproate administration on carnitine metabolism in mouse serum and tissues. 1990 Biochem. Pharmacol. pmid:2105093
Nobes CD et al. The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes. 1990 J. Biol. Chem. pmid:2376580
Perosa F et al. Purification of human immunoglobulins by sequential precipitation with caprylic acid and ammonium sulphate. 1990 J. Immunol. Methods pmid:2324507
Chiang SH et al. Limits of medium-chain and long-chain triacylglycerol utilization by neonatal piglets. 1990 J. Anim. Sci. pmid:2384363
Morton DH and Kelley RI Diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency in the neonatal period by measurement of medium-chain fatty acids in plasma and filter paper blood samples. 1990 J. Pediatr. pmid:2391601
González-Manchón C et al. Ca2(+)-fatty acid interaction in the control of hepatic gluconeogenesis. 1990 Biochim. Biophys. Acta pmid:2310772
Pochapsky SS et al. Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. 1990 Jul-Aug Bioconjug. Chem. pmid:2096916
Demaugre F et al. Infantile form of carnitine palmitoyltransferase II deficiency with hepatomuscular symptoms and sudden death. Physiopathological approach to carnitine palmitoyltransferase II deficiencies. 1991 J. Clin. Invest. pmid:1999498
Auestad N et al. Fatty acid oxidation and ketogenesis by astrocytes in primary culture. 1991 J. Neurochem. pmid:2002348
Dawson DA Additive incidence of developmental malformation for Xenopus embryos exposed to a mixture of ten aliphatic carboxylic acids. 1991 Teratology pmid:1771595
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Richardson A et al. Short chain fatty acids in the terminal ileum accelerate stomach to caecum transit time in the rat. 1991 Gut pmid:2013421
Lepine AJ et al. Effect of colostrum intake on hepatic gluconeogenesis and fatty acid oxidation in the neonatal pig. 1991 J. Anim. Sci. pmid:2066305
Wanders RJ et al. Octanoate and palmitate beta-oxidation in human leukocytes: implications for the rapid diagnosis of fatty acid beta-oxidation disorders. 1991 J. Inherit. Metab. Dis. pmid:1770782
Heales SJ et al. Rapid diagnosis of medium-chain acyl CoA dehydrogenase deficiency by measurement of cis-4-decenoic acid in plasma. 1991 J. Inherit. Metab. Dis. pmid:1779611
Polten BM et al. [Comparison of protein A purification and combined octanoic acid-ammonium sulfate precipitation for the collection of rabbit immunoglobulin]. 1991 Zentralblatt Veterinarmedizin Reihe B pmid:1789026
Sawada T et al. Role of paracellular pathway in nonelectrolyte permeation across rat colon epithelium enhanced by sodium caprate and sodium caprylate. 1991 Pharm. Res. pmid:1798671
Favre-Bulle O et al. Bioconversion of n-octane to octanoic acid by a recombinant Escherichia coli cultured in a two-liquid phase bioreactor. 1991 Biotechnology (N.Y.) pmid:1367010
Grill V et al. Multiple abnormalities in insulin responses to nonglucose nutrients in neonatally streptozotocin diabetic rats. 1991 Endocrinology pmid:1706269
Viegas CA and Sá-Correia I Activation of plasma membrane ATPase of Saccharomyces cerevisiae by octanoic acid. 1991 J. Gen. Microbiol. pmid:1827836
Bhuiyan AK and Pande SV One-step facile synthesis of radioactive acyl-CoA and acylcarnitines using rat liver outer mitochondrial membrane as the enzyme source. 1991 Biochem. Soc. Trans. pmid:1889559
Shenin IuD and Mitrofanova VG [Structure of pentaene antibiotic lavendofuseomycin]. 1991 Antibiot. Khimioter. pmid:1892437
Baum G et al. Clarification of ascites fluid. 1991 BioTechniques pmid:1651092
Kihlberg T et al. Multiple isotopically labeled fatty acids. 1-11C-2,2',3,3'-tetradeutero palmitic and octanoic acid. 1991 Acta Radiol Suppl pmid:1666733
Waldenström A et al. Myocardial disposition of [1-11C]palmitic acid, 2,2',3,3'-tetradeuteropalmitic acid and octanoic acid in the pig. 1991 Acta Radiol Suppl pmid:1666752
Kragh-Hansen U Octanoate binding to the indole- and benzodiazepine-binding region of human serum albumin. 1991 Biochem. J. pmid:1996962
Dombrowski GJ and Swiatek KR Lactate genesis by rat liver and muscle during development. 1991 Pediatr. Res. pmid:1956716
Lundblad JL and Seng RL Inactivation of lipid-enveloped viruses in proteins by caprylate. 1991 Vox Sang. pmid:2031341
Ohtsuka Y and Griffith OW L-carnitine protection in ammonia intoxication. Effect of aminocarnitine on carnitine-dependent metabolism and acute ammonia toxicity. 1991 Biochem. Pharmacol. pmid:2039546
Bohnensack R and Fritz S Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model. 1991 Biochim. Biophys. Acta pmid:2009283
Sakamoto A et al. [A clinical evaluation of reconstruction methods after pancreatoduodenectomy from a view of fat digestion and absorption]. 1991 Nihon Geka Gakkai Zasshi pmid:2014027
Miles JM et al. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. 1991 Jan-Feb JPEN J Parenter Enteral Nutr pmid:1901106
Bjorge SM and Baillie TA Studies on the beta-oxidation of valproic acid in rat liver mitochondrial preparations. 1991 Jul-Aug Drug Metab. Dispos. pmid:1680661
Krahenbuhl S and Brass EP Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:2009071
Noctor TA et al. Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. 1992 J. Chromatogr. pmid:1400761
Wanders RJ and Ijlst L Fatty acid beta-oxidation in leukocytes from control subjects and medium-chain acyl-CoA dehydrogenase deficient patients. 1992 Biochim. Biophys. Acta pmid:1737072
Kristev A et al. Effects of the medium chain octanoic fatty acid on the contractile activity of vascular smooth muscle tissues. 1992 Folia Med (Plovdiv) pmid:1364081
Kim CS et al. Octanoic acid produces accumulation of monoamine acidic metabolites in the brain: interaction with organic anion transport at the choroid plexus. 1992 J. Neurochem. pmid:1372345
Prip-Buus C et al. Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells. 1992 Eur. J. Biochem. pmid:1356769
Stace PB et al. Cyclic AMP and free fatty acids in the longer-term regulation of pyruvate dehydrogenase kinase in rat soleus muscle. 1992 Biochim. Biophys. Acta pmid:1319745