octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chest Pain D002637 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Dyspepsia D004415 5 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Chronic Disease D002908 7 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
McDaniel HG Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. 1975 Am. J. Physiol. pmid:1211489
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Patel TB Effect of sulfonylureas on hepatic fatty acid oxidation. 1986 Am. J. Physiol. pmid:3090894
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Maes BD et al. Gastric emptying flow curves separated from carbon-labeled octanoic acid breath test results. 1998 Am. J. Physiol. pmid:9655697
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
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Ben Cheikh R et al. Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. 1994 Am. J. Physiol. pmid:8203607
Yox DP and Ritter RC Capsaicin attenuates suppression of sham feeding induced by intestinal nutrients. 1988 Am. J. Physiol. pmid:3140678
Hütter JF et al. Effect of fatty acid oxidation on efficiency of energy production in rat heart. 1985 Am. J. Physiol. pmid:4051011
Werner JC et al. Fatty acid and glucose utilization in isolated, working fetal pig hearts. 1983 Am. J. Physiol. pmid:6869527
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Vincent G et al. Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10780941
Kim JY et al. Lipid oxidation is reduced in obese human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052958
Bezaire V et al. Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16219667
Sakata I et al. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19401456
Hommelberg PP et al. Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:18957619