octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Dumping Syndrome D004377 1 associated lipids
Dyspepsia D004415 5 associated lipids
Edema D004487 152 associated lipids
Epilepsy D004827 35 associated lipids
Flatulence D005414 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Giardiasis D005873 3 associated lipids
Glioma D005910 112 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Choi YH et al. Lipoic acid suppresses compound 48/80-induced anaphylaxis-like reaction. 2010 Anat Cell Biol pmid:21267406
Bailly-Chouriberry L et al. Detection of secondary biomarker of met-eGH as a strategy to screen for somatotropin misuse in horseracing. 2008 Analyst pmid:18227952
Meng Y et al. Role of counteranions in polymeric ionic liquid-based solid-phase microextraction coatings for the selective extraction of polar compounds. 2011 Anal. Chim. Acta pmid:21277416
Rodrigues F et al. Development of a dynamic headspace solid-phase microextraction procedure coupled to GC-qMSD for evaluation the chemical profile in alcoholic beverages. 2008 Anal. Chim. Acta pmid:18243877
Kragh-Hansen U et al. Rate-of-dialysis technique: theoretical and practical aspects. 2005 Anal. Biochem. pmid:15802140
Bryant P et al. The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate. 2006 Anal. Biochem. pmid:16500612
Jones JG et al. Determination of acetyl-CoA enrichment in rat heart and skeletal muscle by 1H nuclear magnetic resonance analysis of glutamate in tissue extracts. 1997 Anal. Biochem. pmid:9212871
Kunz D et al. Flow cytometric detection of mitochondrial dysfunction in subpopulations of human mononuclear cells. 1997 Anal. Biochem. pmid:9073359
Hjelmeland LM et al. A new class of nonionic detergents with a gluconamide polar group. 1983 Anal. Biochem. pmid:6869837
Zhu L et al. Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. 2010 Anal Bioanal Chem pmid:20644917
Dietrich B et al. Synthesis, characterization, and high-performance liquid chromatographic evaluation of C14 stationary phases containing branched and unbranched alkyl groups. 2008 Anal Bioanal Chem pmid:18506426
Takahashi H et al. Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry. 2008 Anal Bioanal Chem pmid:18560811
Eggink M et al. Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA. 2010 Anal Bioanal Chem pmid:20238107
Yamamoto K et al. An LC method for monitoring medium-chain fatty acid permeation through CaCo-2 cell monolayers. 2009 Anal Bioanal Chem pmid:19641905
Urquiza M et al. α-Helix peptides designed from EBV-gH protein display higher antigenicity and induction of monocyte apoptosis than the native peptide. 2010 Amino Acids pmid:20473772
McLellan J et al. Comparison of the carbon 13-labeled octanoic acid breath test and ultrasonography for assessment of gastric emptying of a semisolid meal in dogs. 2004 Am. J. Vet. Res. pmid:15566095
Wyse CA et al. Use of the 13C-octanoic acid breath test for assessment of solid-phase gastric emptying in dogs. 2001 Am. J. Vet. Res. pmid:11763185
Valipe SR et al. In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis. 2011 Am. J. Vet. Res. pmid:21355735
Battiprolu PK et al. Sex differences in energy metabolism and performance of teleost cardiac tissue. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17038442
Richards JG et al. Palmitate movement across red and white muscle membranes of rainbow trout. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12969874
El Hafidi M et al. Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:15331379
Librán-Pérez M et al. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. 2012 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:22496361
Sallam HS et al. Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20427716
Darling RA et al. Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760994
Degen L et al. Effect of CCK-1 receptor blockade on ghrelin and PYY secretion in men. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17138722
Barron JT and Gu L Energetic effects of adenosine on vascular smooth muscle. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10644580
Panchal AR et al. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11045976
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Allard MF et al. AMPK and metabolic adaptation by the heart to pressure overload. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:16920812
Labarthe F et al. Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15550523
Vincent G et al. Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:12933348
Kajimoto M et al. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26232235
Kajimoto M et al. Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. 2014 Am. J. Physiol. Heart Circ. Physiol. pmid:24531815
Jørgensen J and Mortensen PB Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11447021
Mizutani M et al. Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501445
Vincent G et al. Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10780941
Kim JY et al. Lipid oxidation is reduced in obese human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052958
Benthem L et al. Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11093916
Bezaire V et al. Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16219667
Cha BS et al. Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15727952
Sakata I et al. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19401456
Tham E et al. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19240252
Hommelberg PP et al. Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:18957619
Bando M et al. Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22114024
Turcotte LP et al. High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11739099
Miller TB Cardiac performance of isolated perfused hearts from alloxan diabetic rats. 1979 Am. J. Physiol. pmid:443443
Lemieux G et al. Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. 1976 Am. J. Physiol. pmid:10736
Morand C et al. Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. 1993 Am. J. Physiol. pmid:8498503
Lemieux G et al. Effect of fluoroacetate on the inhibitory action of ketone bodies and fatty acids on renal ammoniagenesis. 1979 Am. J. Physiol. pmid:464062
Tanner GA et al. Excretion of phenol red by the Necturus kidney. 1979 Am. J. Physiol. pmid:443381