octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Dumping Syndrome D004377 1 associated lipids
Dyspepsia D004415 5 associated lipids
Edema D004487 152 associated lipids
Epilepsy D004827 35 associated lipids
Flatulence D005414 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Giardiasis D005873 3 associated lipids
Glioma D005910 112 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhage D006470 15 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatorenal Syndrome D006530 1 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypothyroidism D007037 32 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Morand C et al. Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. 1993 Am. J. Physiol. pmid:8498503
Consoli A et al. Limitations in the use of [2-14C]acetate for measuring gluconeogenesis in vivo. 1993 Diabetes pmid:8482430
Mabayo RT et al. Improvement of dietary protein utilisation in chicks by medium chain triglyceride. 1993 Br. Poult. Sci. pmid:8467393
Hayden MA et al. Biosynthesis of lipoic acid: characterization of the lipoic acid auxotrophs Escherichia coli W1485-lip2 and JRG33-lip9. 1993 Biochemistry pmid:8466915
Grolier P and Elcombe CR In vitro inhibition of carnitine acyltransferase activity in mitochondria from rat and mouse liver by a diethylhexylphthalate metabolite. 1993 Biochem. Pharmacol. pmid:8452557
Reed KE and Cronan JE Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes. 1993 J. Bacteriol. pmid:8444795
Miura S et al. Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption. 1993 Immunology pmid:8436400
Hossaini AA et al. Experimental induction of caprylate-dependent albumin antibodies. 1977 Jan-Feb Transfusion pmid:841674
Hoffmann GF et al. Physiology and pathophysiology of organic acids in cerebrospinal fluid. 1993 J. Inherit. Metab. Dis. pmid:8412012
Ruderman NB et al. Effect of starvation on muscle glucose metabolism: studies with the isolated perfused rat hindquarter. 1977 Fed. Proc. pmid:838085
Wieland TM et al. Utilization of medium-chain triglycerides by neonatal pigs: effects of emulsification and dose delivered. 1993 J. Anim. Sci. pmid:8349513
Hulsmann WC et al. Imminent ischemia in normal and hypertrophic Langendorff rat hearts; effects of fatty acids and superoxide dismutase monitored by NADH surface fluorescence. 1993 Biochim. Biophys. Acta pmid:8318552
Fitzsimmons ME and Anders MW Fatty acid beta-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. 1993 Sep-Oct Chem. Res. Toxicol. pmid:8292744
Viegas CA et al. Regulation of the expression of the H(+)-ATPase genes PMA1 and PMA2 during growth and effects of octanoic acid in Saccharomyces cerevisiae. 1994 Biochim. Biophys. Acta pmid:8286419
Odle J et al. Emulsification and fatty acid chain length affect the kinetics of [14C]-medium-chain triacylglycerol utilization by neonatal piglets. 1994 J. Nutr. pmid:8283298
Dieuaide M et al. Effects of glucose starvation on the oxidation of fatty acids by maize root tip mitochondria and peroxisomes: evidence for mitochondrial fatty acid beta-oxidation and acyl-CoA dehydrogenase activity in a higher plant. 1993 Biochem. J. pmid:8250843
Guimbretiere J et al. [A further case of albumin auto-agglutination in a blood donor]. 1976 Rev. Fr. Transfus. Immunohematol. pmid:824703
Martín-Requero A et al. Reciprocal changes in gluconeogenesis and ureagenesis induced by fatty acid oxidation. 1993 Metab. Clin. Exp. pmid:8246772
Adams SH and Odle J Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. 1993 Am. J. Physiol. pmid:8238444
Alvarez CV et al. Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells. 1993 Neuroendocrinology pmid:8232763