octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cessna AJ and Grover R | Exposure of ground-rig applicators to the herbicide bromoxynil applied as a 1:1 mixture of butyrate and octanoate. | 2002 | Arch. Environ. Contam. Toxicol. | pmid:11910467 |
Jong-Yeon K et al. | Long- and medium-chain fatty acid oxidation is increased in exercise-trained human skeletal muscle. | 2002 | Metab. Clin. Exp. | pmid:11912554 |
Robinson MK | Population differences in acute skin irritation responses. Race, sex, age, sensitive skin and repeat subject comparisons. | 2002 | Contact Derm. | pmid:11918601 |
Tenreiro S et al. | AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11922628 |
Gravena C et al. | Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. | 2002 | J. Endocrinol. | pmid:11927386 |
Henry GE et al. | Antioxidant and cyclooxygenase activities of fatty acids found in food. | 2002 | J. Agric. Food Chem. | pmid:11929276 |
Kuge Y et al. | In vitro uptake of [1-14C]Octanoate in brain slices of rats: basic studies for assessing [1-11C]Octanoate as a PET tracer of glial functions. | 2002 | Nucl. Med. Biol. | pmid:11929699 |
Ahmad R and Magan N | Microfloral contamination and hydrolytic enzyme differences between monsooned and non-monsooned coffees. | 2002 | Lett. Appl. Microbiol. | pmid:11940159 |
Hansford RG and Johnson RN | The steady state concentrations of coenzyme A-SH and coenzyme A thioester, citrate, and isocitrate during tricarboxylate cycle oxidations in rabbit heart mitochondria. | 1975 | J. Biol. Chem. | pmid:1194259 |
Jomain-Baum M and Hanson RW | Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia. | 1975 | J. Biol. Chem. | pmid:1194271 |
Wright TC et al. | Inhibition of fatty acid synthesis in bovine mammary homogenate by palmitic acid is not a detergent effect. | 2002 | J. Dairy Sci. | pmid:11949869 |
Wanten GJ et al. | Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. | 2002 | Eur. J. Clin. Invest. | pmid:11952815 |
Sarnatskaya VV et al. | Effect of protein-bound uraemic toxins on the thermodynamic characteristics of human albumin. | 2002 | Biochem. Pharmacol. | pmid:11960605 |
Buse MG et al. | Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats. | 1975 | Biochem. J. | pmid:1200982 |
Hoshimoto A et al. | Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. | 2002 | Br. J. Pharmacol. | pmid:12010777 |
Schmidt-Wilcke HA et al. | Effect of fatty acids on the stimulated gastric secretion in man. | 1975 | Digestion | pmid:1201821 |
Hang X et al. | PCR cloning of polyhydroxyalkanoate biosynthesis genes from Burkholderia caryophylli and their functional expression in recombinant Escherichia coli. | 2002 | FEMS Microbiol. Lett. | pmid:12023076 |
Horisawa E et al. | Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit. | 2002 | Pharm. Res. | pmid:12033371 |
Tachibana S et al. | Octanoate inhibits very low-density lipoprotein secretion in primary cultures of chicken hepatocytes. | 2002 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:12044771 |
von Glutz G and Walter P | Compartmentation of acetyl-coA in rat-liver mitochondria. | 1975 | Eur. J. Biochem. | pmid:1204636 |