octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Crohn Disease D003424 12 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Starvation D013217 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Liu P et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. 2013 Appl. Microbiol. Biotechnol. pmid:23435986
Oiso S et al. Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. 2013 J Biomol Screen pmid:23704134
Frauches TS et al. Bothropic antivenom based on monoclonal antibodies, is it possible? 2013 Toxicon pmid:23732123
Leonard PH et al. Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid. 2013 Fertil. Steril. pmid:23602317
Coenen MJ et al. Polymorphism in porphyrin monolayers: the relation between adsorption configuration and molecular conformation. 2013 Phys Chem Chem Phys pmid:23620134
Bernardino K and de Moura AF Aggregation thermodynamics of sodium octanoate micelles studied by means of molecular dynamics simulations. 2013 J Phys Chem B pmid:23697593
Roda A et al. Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project. 2013 World J. Gastroenterol. pmid:23599647
Morrill KM et al. Estimate of serum immunoglobulin G concentration using refractometry with or without caprylic acid fractionation. 2013 J. Dairy Sci. pmid:23664346
Fonseca CR et al. Storage of refrigerated raw goat milk affecting the quality of whole milk powder. 2013 J. Dairy Sci. pmid:23664351
Costello PJ et al. Synthesis of fruity ethyl esters by acyl coenzyme A: alcohol acyltransferase and reverse esterase activities in Oenococcus oeni and Lactobacillus plantarum. 2013 J. Appl. Microbiol. pmid:23216623
Brun AC et al. Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. 2013 Clin Nutr pmid:23196118
Midelfort KS et al. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. 2013 Protein Eng. Des. Sel. pmid:23012440
Librán-Pérez M et al. Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23010243
Librán-Pérez M et al. Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. 2013 PLoS ONE pmid:23533628
Librán-Pérez M et al. In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23542747
Guo H et al. Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. 2013 Bioorg. Med. Chem. Lett. pmid:24018188
Harmancey R et al. Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. 2013 FASEB J. pmid:23825227
Shilling M et al. Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. 2013 J Med Food pmid:24328700
Hungate EA et al. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. 2013 Genetics pmid:24037270
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902