octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yanai S et al. | Antitumor effect of arterial administration of a medium-chain triglyceride solution of an angiogenesis inhibitor, TNP-470, in rabbits bearing VX-2 carcinoma. | 1995 | Pharm. Res. | pmid:7479548 |
Cheruvallath VK et al. | The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication. | 1996 | Pharm. Res. | pmid:8668670 |
Prajapati HN et al. | A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. | 2012 | Pharm. Res. | pmid:21861203 |
Trusk TC and Stein EA | Effect of heroin-conditioned auditory stimuli on cerebral functional activity in rats. | 1988 | Pharmacol. Biochem. Behav. | pmid:3227045 |
Chen CY et al. | Ghrelin gene products and the regulation of food intake and gut motility. | 2009 | Pharmacol. Rev. | pmid:20038570 |
Mahadevia PJ | The pocketbook: Pharmacoeconomic issues related to intravenous immunoglobulin therapy. | 2005 | Pharmacotherapy | pmid:16229680 |
Latere DJ et al. | Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization. | 2008 | Pharmazie | pmid:18444514 |
Lala AK and Koppaka V | Transverse location of new fluorene based depth dependent fluorescent probes in membranes--quenching studies with 9,10-dibromostearic acid. | 1989 | Photochem. Photobiol. | pmid:2772065 |
Pereira RF et al. | What drives the precipitation of long-chain calcium carboxylates (soaps) in aqueous solution? | 2012 | Phys Chem Chem Phys | pmid:22513819 |
Dzikovski B et al. | Multifrequency ESR study of spin-labeled molecules in inclusion compounds with cyclodextrins. | 2009 | Phys Chem Chem Phys | pmid:19639141 |
Coenen MJ et al. | Polymorphism in porphyrin monolayers: the relation between adsorption configuration and molecular conformation. | 2013 | Phys Chem Chem Phys | pmid:23620134 |
Polácek H et al. | Study of cough in anaesthetized cats with experimental pulmonary oedema. | 1986 | Physiol Bohemoslov | pmid:2950532 |
Gann VK and Hardin CD | Acetate or octanoate increases glycogenolysis in smooth muscle as determined by 13C-NMR. | 1997 | Physiol Chem Phys Med NMR | pmid:9353955 |
Jambor de Sousa UL et al. | Caprylic acid infusion acts in the liver to decrease food intake in rats. | 2006 | Physiol. Behav. | pmid:16360711 |
Librán-Pérez M et al. | Central administration of oleate or octanoate activates hypothalamic fatty acid sensing and inhibits food intake in rainbow trout. | 2014 | Physiol. Behav. | pmid:24631300 |
Jambor de Sousa UL et al. | Hepatic-portal oleic acid inhibits feeding more potently than hepatic-portal caprylic acid in rats. | 2006 | Physiol. Behav. | pmid:16890966 |
MacDonald ML et al. | Aversion of the cat to dietary medium-chain triglycerides and caprylic acid. | 1985 | Physiol. Behav. | pmid:4070410 |
Hiraoka T et al. | Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats. | 2003 | Physiol. Behav. | pmid:12954413 |
Corona-Castañeda B et al. | Modulators of antibiotic activity from Ipomoea murucoides. | 2013 | Phytochemistry | pmid:23920226 |
Waltenberger B et al. | Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine. | 2011 | Phytomedicine | pmid:20851587 |
Vincenzini MT et al. | The Effects of Octanoate and Oleate on Isocitrate Lyase Activity during the Germination of Pinus pinea Seeds. | 1973 | Plant Physiol. | pmid:16658603 |
Lawo NC et al. | The volatile metabolome of grapevine roots: first insights into the metabolic response upon phylloxera attack. | 2011 | Plant Physiol. Biochem. | pmid:21764593 |
Crane J et al. | Triacylglycerols determine the unusual storage physiology of Cuphea seed. | 2003 | Planta | pmid:12743824 |
Wiberg E et al. | The distribution of caprylate, caprate and laurate in lipids from developing and mature seeds of transgenic Brassica napus L. | 2000 | Planta | pmid:11219581 |
Won HS et al. | Mechanism of action of Brazilin on gluconeogenesis in isolated rat hepatocytes. | 2004 | Planta Med. | pmid:15368663 |
Gross L | Can a taste for poison drive speciation? | 2007 | PLoS Biol. | pmid:20076673 |
Matsuo T et al. | Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia. | 2007 | PLoS Biol. | pmid:17456006 |
Eren E et al. | Substrate specificity within a family of outer membrane carboxylate channels. | 2012 | PLoS Biol. | pmid:22272184 |
Saft C et al. | No evidence of impaired gastric emptying in early Huntington's Disease. | 2011 | PLoS Curr | pmid:22130331 |
de Silva HA et al. | Low-dose adrenaline, promethazine, and hydrocortisone in the prevention of acute adverse reactions to antivenom following snakebite: a randomised, double-blind, placebo-controlled trial. | 2011 | PLoS Med. | pmid:21572992 |
Casewell NR et al. | Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom. | 2010 | PLoS Negl Trop Dis | pmid:21049058 |
Abubakar IS et al. | Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria. | 2010 | PLoS Negl Trop Dis | pmid:20668549 |
Vargas M et al. | Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea. | 2011 | PLoS Negl Trop Dis | pmid:21610854 |
Brown NI | Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. | 2012 | PLoS Negl Trop Dis | pmid:22679521 |
El-Ekiaby M et al. | Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. | 2015 | PLoS Negl Trop Dis | pmid:25719558 |
Brilli F et al. | Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction "time-of-flight" mass spectrometry (PTR-TOF). | 2011 | PLoS ONE | pmid:21637822 |
Hauser PV et al. | Novel siRNA delivery system to target podocytes in vivo. | 2010 | PLoS ONE | pmid:20209128 |
Brault G et al. | Isolation and characterization of EstC, a new cold-active esterase from Streptomyces coelicolor A3(2). | 2012 | PLoS ONE | pmid:22396747 |
Takahashi K et al. | Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism. | 2009 | PLoS ONE | pmid:19119319 |
Jawara M et al. | Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia. | 2011 | PLoS ONE | pmid:21637337 |
González-Mas MC et al. | Comparative analysis of the volatile fraction of fruit juice from different Citrus species. | 2011 | PLoS ONE | pmid:21818287 |
Okumu FO et al. | Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. | 2010 | PLoS ONE | pmid:20126628 |
Berna AZ et al. | Bio-benchmarking of electronic nose sensors. | 2009 | PLoS ONE | pmid:19641604 |
Murzyn A et al. | Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. | 2010 | PLoS ONE | pmid:20706577 |
Gumel AM et al. | Biosynthesis and characterization of polyhydroxyalkanoates copolymers produced by Pseudomonas putida Bet001 isolated from palm oil mill effluent. | 2012 | PLoS ONE | pmid:23028854 |
Liberato MV et al. | Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and pan-PPAR partial agonists. | 2012 | PLoS ONE | pmid:22649490 |
Jin M et al. | A rapid subtractive immunization method to prepare discriminatory monoclonal antibodies for food E. coli O157:H7 contamination. | 2012 | PLoS ONE | pmid:22347466 |
Caballero E et al. | Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases. | 2014 | PLoS ONE | pmid:25248107 |
Librán-Pérez M et al. | Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. | 2013 | PLoS ONE | pmid:23533628 |
Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |