octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thayer WS | Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. | 1984 | Biochem. Pharmacol. | pmid:6712730 |
Otto DA | Relationship of the ATP/ADP ratio to the site of octanoate activation. | 1984 | J. Biol. Chem. | pmid:6715356 |
Habeeb AF and Francis RD | Preparation of human immunoglobulin by caprylic acid precipitation. | 1984 | Prep. Biochem. | pmid:6718324 |
Reed WD et al. | A double-isotope method for the measurement of ketone-body turnover in the rat. Effect of L-alanine. | 1984 | Biochem. J. | pmid:6721850 |
Soboll S et al. | Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. | 1984 | Eur. J. Biochem. | pmid:6723661 |
Aurousseau B et al. | [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. | 1984 | Reprod Nutr Dev | pmid:6729239 |
Chen V et al. | Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate. | 1984 | Horm. Metab. Res. | pmid:6735347 |
Ross PD et al. | Thermal stability of human albumin measured by differential scanning calorimetry. II. Effects of isomers of N-acetyltryptophanate and tryptophanate, pH, reheating, and dimerization. | 1984 | Vox Sang. | pmid:6741029 |
Yu MW and Finlayson JS | Stabilization of human albumin by caprylate and acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741030 |
Shrake A et al. | Thermal stability of human albumin measured by differential scanning calorimetry. I. Effects of caprylate and N-acetyltryptophanate. | 1984 | Vox Sang. | pmid:6741034 |
Soboll S et al. | Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell. | 1984 | Biochem. J. | pmid:6743276 |
Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
Elliott JR et al. | The asymmetrical effects of some ionized n-octyl derivatives on the sodium current of the giant axon of Loligo forbesi. | 1984 | J. Physiol. (Lond.) | pmid:6747855 |
White RH | Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. | 1980 | Biochemistry | pmid:6766313 |
ChacÃn J et al. | Role of fatty acid oxidation in mechanism of action of gastric secretagogues. | 1980 | Am. J. Physiol. | pmid:6768310 |
Chan SC | Monitoring serum valproic acid by gas chromatography with electron-capture detection. | 1980 | Clin. Chem. | pmid:6774836 |
Bijlsma R | Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. | 1980 | Biochem. Genet. | pmid:6781470 |
Derr RF and Zieve L | Effect of fatty acids on the disposition of ammonia. | 1976 | J. Pharmacol. Exp. Ther. | pmid:6789 |
Abbott FS et al. | Valproic acid analysis in saliva and serum using selected ion monitoring (electron ionization) of the tert.-butyldimethylsilyl derivatives. | 1982 | J. Chromatogr. | pmid:6801067 |
Palabost-Charles L | Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster. | 1982 | Biochem. Genet. | pmid:6810873 |
Buchowicz I et al. | Anti-pseudomonas immunoglobulin. II. Preparation of purified sheep immunoglobulins. | 1981 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:6812541 |
Ledden DJ et al. | Characterization of fragments of human albumin purified by Cibacron blue F3GA affinity chromatography. | 1982 | Biochem. J. | pmid:6814424 |
Windus-Podehl G et al. | Encephalopathic effect of phenol in rats. | 1983 | J. Lab. Clin. Med. | pmid:6833829 |
Stange EF and Dietschy JM | Absolute rates of cholesterol synthesis in rat intestine in vitro and in vivo: a comparison of different substrates in slices and isolated cells. | 1983 | J. Lipid Res. | pmid:6833883 |
Zabłocki K et al. | The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. | 1983 | Biochim. Biophys. Acta | pmid:6838901 |
Almås I et al. | The action of vasopressin and calcium on palmitate metabolism in hepatocytes and isolated mitochondria from rat liver. | 1983 | Arch. Biochem. Biophys. | pmid:6847192 |
Werner JC et al. | Fatty acid and glucose utilization in isolated, working newborn pig hearts. | 1983 | Am. J. Physiol. | pmid:6849379 |
Latipää PM et al. | Regulation of fatty acid oxidation in heart muscle. Effects of pyruvate and dichloroacetate. | 1983 | Biochim. Biophys. Acta | pmid:6849964 |
Mayorek N and Bar-Tana J | Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. | 1983 | J. Biol. Chem. | pmid:6853505 |
Bell FP | Effect of the plasticizer di(2-ethylhexyl) adipate (dioctyladipate, DOA) on lipid metabolism in the rat: I. Inhibition of cholesterolgenesis and modification of phospholipid synthesis. | 1983 | Lipids | pmid:6855481 |
Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
Werner JC et al. | Fatty acid and glucose utilization in isolated, working fetal pig hearts. | 1983 | Am. J. Physiol. | pmid:6869527 |
Hjelmeland LM et al. | A new class of nonionic detergents with a gluconamide polar group. | 1983 | Anal. Biochem. | pmid:6869837 |
Pégorier JP et al. | Metabolic fate of non-esterified fatty acids in isolated hepatocytes from newborn and young pigs. Evidence for a limited capacity for oxidation and increased capacity for esterification. | 1983 | Biochem. J. | pmid:6870859 |
Shapiro IM et al. | Studies of nucleotides of growth-plate cartilage: evidence linking changes in cellular metabolism with cartilage calcification. | 1983 | Biosci. Rep. | pmid:6871381 |
Shimizu H | [Comparative studies on perfused adult and fetal guinea pig liver metabolism before and after anoxia loadings, with special reference to intracellular redox state]. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6875338 |
Rabinowitz JL et al. | Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's disease. | 1983 | Lipids | pmid:6877040 |
Bünger R et al. | Energy utilization and pyruvate as determinants of pyruvate dehydrogenase in norepinephrine-stimulated heart. | 1983 | Pflugers Arch. | pmid:6878010 |
Bagnasco SM et al. | The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis. | 1983 | Metab. Clin. Exp. | pmid:6888270 |
Caffier G et al. | The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. | 1980 | Pflugers Arch. | pmid:6966791 |
Kössler F et al. | Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. | 1980 | Chem. Biol. Interact. | pmid:6967777 |
Caffier G and Küchler G | [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. | 1980 | Acta Biol. Med. Ger. | pmid:6969509 |
Caffier G et al. | Contractile properties of isolated frog skeletal muscles under the influence of Na-octanoate. | 1982 | Acta Biol. Med. Ger. | pmid:6981273 |
Barth CA et al. | Morphology and metabolism of adult rat hepatocytes in primary culture. | 1980 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6997170 |
Borg LA | Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. | 1981 | Acta Endocrinol. | pmid:7010865 |
Zwiebel FM et al. | Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. | 1982 | Biochemistry | pmid:7074018 |
Haidukewych D et al. | Monitoring octanoic and decanoic acids in plasma from children with intractable epilepsy treated with medium-chain triglyceride diet. | 1982 | Clin. Chem. | pmid:7074833 |
Odessey R and Chace KV | Utilization of endogenous lipid, glycogen, and protein by rabbit aorta. | 1982 | Am. J. Physiol. | pmid:7091374 |
Garcia-Esteller SC et al. | Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo. | 1982 | Int. J. Biochem. | pmid:7106360 |
Zeneroli ML et al. | Visual evoked potentials in encephalopathy induced by galactosamine, ammonia, dimethyldisulfide, and octanoic acid. | 1982 Sep-Oct | Hepatology | pmid:7118066 |