octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ballow M et al. | Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%). | 2003 | Vox Sang. | pmid:12670369 |
van de Casteele M et al. | Oxidative breakdown of octanoic acid is maintained in patients with cirrhosis despite advanced disease. | 2003 | Neurogastroenterol. Motil. | pmid:12680910 |
Sutton DG et al. | Validation of the 13C-octanoic acid breath test for measurement of equine gastric emptying rate of solids using radioscintigraphy. | 2003 | Equine Vet. J. | pmid:12553459 |
Heurtault B et al. | The influence of lipid nanocapsule composition on their size distribution. | 2003 | Eur J Pharm Sci | pmid:12554073 |
Gimeno RE et al. | Characterization of a heart-specific fatty acid transport protein. | 2003 | J. Biol. Chem. | pmid:12556534 |
Nowak-Thompson B et al. | 2,5-dialkylresorcinol biosynthesis in Pseudomonas aurantiaca: novel head-to-head condensation of two fatty acid-derived precursors. | 2003 | J. Bacteriol. | pmid:12533461 |
Wyse CA et al. | A comparison of the rate of recovery of 13CO2 in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog. | 2003 | Res. Vet. Sci. | pmid:12589736 |
Jordan SW and Cronan JE | The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase. | 2003 | J. Bacteriol. | pmid:12591875 |
Wu HA et al. | Rapid differentiation between short-chain-length and medium-chain-length polyhydroxyalkanoate-accumulating bacteria with spectrofluorometry. | 2003 | J. Microbiol. Methods | pmid:12609733 |
Walton ME et al. | Relative rates of anaplerotic flux in rested and contracted rat skeletal muscle measured by 13C NMR spectroscopy. | 2003 | J. Physiol. (Lond.) | pmid:12611923 |
Jones PM et al. | Accumulation of 3-hydroxy-fatty acids in the culture medium of long-chain L-3-hydroxyacyl CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein-deficient skin fibroblasts: implications for medium chain triglyceride dietary treatment of LCHAD deficiency. | 2003 | Pediatr. Res. | pmid:12621125 |
Chen CP et al. | Infrared spectrometry based 13C-octanoic acid breath test in measuring human solid gastric emptying. | 2003 | J. Gastroenterol. Hepatol. | pmid:12519222 |
Massillon D et al. | Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. | 2003 | J. Biol. Chem. | pmid:12915406 |
Mori S et al. | Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. | 2003 | J. Cereb. Blood Flow Metab. | pmid:12679720 |
Iwahashi H et al. | The formation of the 7-carboxyheptyl radical from 13-hydroperoxy-9,11-octadecadienoic acid catalyzed by hemoglobin and myoglobin under anaerobic conditions. | 2003 | J. Biochem. | pmid:12801921 |
Chew CG et al. | Simultaneous 13C/14C dual isotope breath test measurement of gastric emptying of solid and liquid in normal subjects and patients: comparison with scintigraphy. | 2003 | Nucl Med Rev Cent East Eur | pmid:14600930 |
Osborn-Barnes HT and Akoh CC | Copper-catalyzed oxidation of a structured lipid-based emulsion containing alpha-tocopherol and citric acid: influence of pH and NaCl. | 2003 | J. Agric. Food Chem. | pmid:14582985 |
Osborn-Barnes HT and Akoh CC | Effects of alpha-tocopherol, beta-carotene, and soy isoflavones on lipid oxidation of structured lipid-based emulsions. | 2003 | J. Agric. Food Chem. | pmid:14582986 |
Sakaki K and Itoh N | Optical resolution of racemic 2-hydroxy octanoic acid by lipase-catalyzed hydrolysis in a biphasic membrane reactor. | 2003 | Biotechnol. Lett. | pmid:14584912 |
Marounek M et al. | Susceptibility of Escherichia coli to C2-C18 fatty acids. | 2003 | Folia Microbiol. (Praha) | pmid:15058184 |
Lai CY and Cronan JE | Beta-ketoacyl-acyl carrier protein synthase III (FabH) is essential for bacterial fatty acid synthesis. | 2003 | J. Biol. Chem. | pmid:14523010 |
Wang Z and Zhang Q | [Study on pulmonary delivery system of salmon calcitonin in rats]. | 2003 | Beijing Da Xue Xue Bao | pmid:12914259 |
Ho TS et al. | Liquid-phase microextraction of hydrophilic drugs by carrier-mediated transport. | 2003 | J Chromatogr A | pmid:12862372 |
Kudo N and Kawashima Y | Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. | 2003 | J Toxicol Sci | pmid:12820537 |
Claessens YE et al. | Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. | 2003 | Crit Care | pmid:12793872 |
Macko T et al. | Elution behavior of polyethylene in polar mobile phases on a non-polar sorbent. | 2003 | J Chromatogr A | pmid:12647822 |
Li C et al. | Covalent binding of 2-phenylpropionyl-S-acyl-CoA thioester to tissue proteins in vitro. | 2003 | Drug Metab. Dispos. | pmid:12756204 |
Piette V et al. | Enantiomer separation of N-protected amino acids by non-aqueous capillary electrophoresis and high-performance liquid chromatography with tert.-butyl carbamoylated quinine in either the background electrolyte or the stationary phase. | 2003 | J Chromatogr A | pmid:12613837 |
Campbell JW et al. | A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic beta-oxidation pathway. | 2003 | Mol. Microbiol. | pmid:12535077 |
Takenaka T et al. | Fatty acids as an energy source for the operation of axoplasmic transport. | 2003 | Brain Res. | pmid:12711076 |
Pêgo AP et al. | Physical properties of high molecular weight 1,3-trimethylene carbonate and D,L-lactide copolymers. | 2003 | J Mater Sci Mater Med | pmid:15348396 |
Cai Q et al. | Synthesis and characterization of biodegradable polylactide-grafted dextran and its application as compatilizer. | 2003 | Biomaterials | pmid:12809784 |
Winiarska K et al. | Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. | 2003 | Metab. Clin. Exp. | pmid:12800101 |
Hamel FG et al. | In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. | 2003 | Endocrinology | pmid:12746301 |
Iwasaki Y et al. | Reduced adhesion of blood cells to biodegradable polymers by introducing phosphorylcholine moieties. | 2003 | J Biomed Mater Res A | pmid:12734808 |
Theakston RD et al. | Report of a WHO workshop on the standardization and control of antivenoms. | 2003 | Toxicon | pmid:12676433 |
Hara Y et al. | Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes. | 2003 | Immunol. Lett. | pmid:12644315 |
Knight VK et al. | Biotransformation of 3,5-dibromo-4-hydroxybenzonitrile under denitrifying, Fe(III)-reducing, sulfidogenic, and methanogenic conditions. | 2003 | Environ. Toxicol. Chem. | pmid:12627640 |
Nguyen CA et al. | Cell interaction studies of PLA-MePEG nanoparticles. | 2003 | Int J Pharm | pmid:12615412 |
Oettl K et al. | An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767923 |
Small RW | An X-ray diffraction study of partially ordered electron density in clathrates of Dianin's compound that include simple carboxylic acids. | 2003 | Acta Crystallogr., B | pmid:12554979 |
St-Onge MP et al. | Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. | 2003 | Int. J. Obes. Relat. Metab. Disord. | pmid:12532160 |
Adamczak M | Characteristic of fungal lipases and their application in synthesis of structered lipids. | 2003 | Commun. Agric. Appl. Biol. Sci. | pmid:24757817 |
Maes BD et al. | Gastric emptying in renal failure patients using the 13C-octanoic acid breath test: facts and artifacts. | 2002 Nov-Dec | Perit Dial Int | pmid:12556082 |
Green PR et al. | Formation of short chain length/medium chain length polyhydroxyalkanoate copolymers by fatty acid beta-oxidation inhibited Ralstonia eutropha. | 2002 Jan-Feb | Biomacromolecules | pmid:11866575 |
Schoonjans R et al. | The 13C-octanoic acid breath test: validation of a new noninvasive method of measuring gastric emptying in rats. | 2002 | Neurogastroenterol. Motil. | pmid:12061914 |
Bender JL et al. | Site-isolated luminescent europium complexes with polyester macroligands: metal-centered heteroarm stars and nanoscale assemblies with labile block junctions. | 2002 | J. Am. Chem. Soc. | pmid:12121083 |
Giannakou SA et al. | In vitro evaluation of nimodipine permeation through human epidermis using response surface methodology. | 2002 | Int J Pharm | pmid:12086718 |
GarcÃa-Villafranca J and Castro J | Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. | 2002 | Biochem. Pharmacol. | pmid:12093476 |
Slater C et al. | Bulk and compound specific analysis of stool lipid confirm that the "missing" 13C in the mixed triacylglycerol breath test is not in the stool. | 2002 | Food Nutr Bull | pmid:12362811 |
Tachibana S et al. | Octanoate inhibits very low-density lipoprotein secretion in primary cultures of chicken hepatocytes. | 2002 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:12044771 |
Diard S et al. | Accumulation of poly(3-hydroxybutyrate) from octanoate in different pseudomonas belonging to the rRNA homology group I. | 2002 | Syst. Appl. Microbiol. | pmid:12353870 |
Horisawa E et al. | Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit. | 2002 | Pharm. Res. | pmid:12033371 |
Chuang VT and Otagiri M | How do fatty acids cause allosteric binding of drugs to human serum albumin? | 2002 | Pharm. Res. | pmid:12425462 |
Wright TC et al. | Inhibition of fatty acid synthesis in bovine mammary homogenate by palmitic acid is not a detergent effect. | 2002 | J. Dairy Sci. | pmid:11949869 |
Fomuso LB et al. | Metal-catalyzed oxidation of a structured lipid model emulsion. | 2002 | J. Agric. Food Chem. | pmid:12428969 |
Tenreiro S et al. | AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11922628 |
Giesy JG et al. | Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. | 2002 | J. Dairy Sci. | pmid:12214995 |
Slater C et al. | Analysis of 13C-mixed triacylglycerol in stool by bulk (EA-IRMS) and compound specific (GC/MS) methods. | 2002 | Isotopes Environ Health Stud | pmid:12219984 |
Abdel-Hamid ME et al. | Stability study of the anticonvulsant enaminone (E118) using HPLC and LC-MS. | 2002 | J Pharm Biomed Anal | pmid:11682230 |
Gwak HS et al. | Effect of vehicles and enhancers on the in vitro permeation of melatonin through hairless mouse skin. | 2002 | Arch. Pharm. Res. | pmid:12135116 |
Sun CQ et al. | The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase. | 2002 | Chem. Biol. Interact. | pmid:12076524 |
Henry GE et al. | Antioxidant and cyclooxygenase activities of fatty acids found in food. | 2002 | J. Agric. Food Chem. | pmid:11929276 |
Gwak HS and Chun IK | Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. | 2002 | Int J Pharm | pmid:11891070 |
Liggins RT and Burt HM | Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations. | 2002 | Adv. Drug Deliv. Rev. | pmid:11897145 |
Sarnatskaya VV et al. | Effect of protein-bound uraemic toxins on the thermodynamic characteristics of human albumin. | 2002 | Biochem. Pharmacol. | pmid:11960605 |
Cessna AJ and Grover R | Exposure of ground-rig applicators to the herbicide bromoxynil applied as a 1:1 mixture of butyrate and octanoate. | 2002 | Arch. Environ. Contam. Toxicol. | pmid:11910467 |
Wanten GJ et al. | Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. | 2002 | Eur. J. Clin. Invest. | pmid:11952815 |
Jelen HH et al. | Influence of octanoic acid addition to medium on some volatile compounds and PR-toxin biosynthesis by Penicillium roqueforti. | 2002 | Lett. Appl. Microbiol. | pmid:12081547 |
Patel S and Shibamoto T | Effect of different strains of Saccharomyces cerevisiae on production of volatiles in Napa Gamay wine and Petite Sirah wine. | 2002 | J. Agric. Food Chem. | pmid:12236692 |
Piette V et al. | Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors. | 2002 | J Chromatogr A | pmid:12831205 |
Buclin T et al. | Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers. | 2002 | J. Bone Miner. Res. | pmid:12162502 |
Spildo K and Blokhus AM | Adsorption from the organic phase in the octanoic acid-octylamine-silica system. | 2002 | J Colloid Interface Sci | pmid:16290813 |
Banks WA et al. | Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12130749 |
Leite-Moreira AF et al. | Modulation of myocardial function by pyruvate. | 2002 | Rev Port Cardiol | pmid:12090129 |
Dutta P and Fendler JH | Preparation of cadmium sulfide nanoparticles in self-reproducing reversed micelles. | 2002 | J Colloid Interface Sci | pmid:16290439 |
Jørgensen JR et al. | Absorption and metabolism of octanoate by the rat colon in vivo: concentration dependency and influence of alternative fuels. | 2002 | Gut | pmid:12077096 |
Hang X et al. | PCR cloning of polyhydroxyalkanoate biosynthesis genes from Burkholderia caryophylli and their functional expression in recombinant Escherichia coli. | 2002 | FEMS Microbiol. Lett. | pmid:12023076 |
Ahmad R and Magan N | Microfloral contamination and hydrolytic enzyme differences between monsooned and non-monsooned coffees. | 2002 | Lett. Appl. Microbiol. | pmid:11940159 |
Kawaguchi T et al. | Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. | 2002 | J. Biol. Chem. | pmid:11724780 |
Okamoto K et al. | Production of gamma-lactones by the brown-rot basidiomycete Piptoporus soloniensis. | 2002 | J. Biosci. Bioeng. | pmid:16233291 |
Frederich M and Balschi JA | The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart. | 2002 | J. Biol. Chem. | pmid:11707445 |
Sugihara A et al. | Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506971 |
Pera P et al. | Influence of mastication on gastric emptying. | 2002 | J. Dent. Res. | pmid:11876271 |
Robinson MK | Population differences in acute skin irritation responses. Race, sex, age, sensitive skin and repeat subject comparisons. | 2002 | Contact Derm. | pmid:11918601 |
Bluck LJ et al. | Measurement of gastric emptying in man using deuterated octanoic acid. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11754258 |
Turcotte LP et al. | High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11739099 |
Iwahashi H et al. | Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide. | 2002 | Biochem. J. | pmid:11742529 |
GarcÃa M et al. | Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation. | 2002 | Biologicals | pmid:12127316 |
Coort SL et al. | Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake. | 2002 | Mol. Cell. Biochem. | pmid:12479588 |
Korneyeva M et al. | Enveloped virus inactivation by caprylate: a robust alternative to solvent-detergent treatment in plasma derived intermediates. | 2002 | Biologicals | pmid:12127317 |
Bromer MQ et al. | Simultaneous measurement of gastric emptying with a simple muffin meal using [13C]octanoate breath test and scintigraphy in normal subjects and patients with dyspeptic symptoms. | 2002 | Dig. Dis. Sci. | pmid:12141833 |
Ward DS et al. | Pharmacodynamics and pharmacokinetics of propofol in a medium-chain triglyceride emulsion. | 2002 | Anesthesiology | pmid:12459665 |
Angelos MG et al. | Glucose, insulin and potassium (GIK) during reperfusion mediates improved myocardial bioenergetics. | 2002 | Resuscitation | pmid:12458070 |
Bianchi M and Capurso L | Effects of guar gum, ispaghula and microcrystalline cellulose on abdominal symptoms, gastric emptying, orocaecal transit time and gas production in healthy volunteers. | 2002 | Dig Liver Dis | pmid:12408456 |
Olivier JC et al. | Synthesis of pegylated immunonanoparticles. | 2002 | Pharm. Res. | pmid:12240939 |
Jagielski AK et al. | Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules. | 2002 | Arch. Biochem. Biophys. | pmid:12147256 |
Chassard D et al. | Effects of subhypnotic doses of propofol on gastric emptying in volunteers. | 2002 | Anesthesiology | pmid:12131109 |
Babu E et al. | Role of human organic anion transporter 4 in the transport of ochratoxin A. | 2002 | Biochim. Biophys. Acta | pmid:12063169 |
Dichtelmüller H et al. | Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. | 2002 | Biologicals | pmid:12127315 |