octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lemarié F et al. | Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. | 2016 | Biochim. Biophys. Acta | pmid:27317984 |
Sawatani Y et al. | Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. | 2016 | Bioorg. Med. Chem. | pmid:27301681 |
Kubota K et al. | The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. | 2016 | Eur J Pharm Sci | pmid:26965004 |
Wang L et al. | Octanoylated ghrelin attenuates angiogenesis induced by oxLDL in human coronary artery endothelial cells via the GHSR1a-mediated NF-κB pathway. | 2015 | Metab. Clin. Exp. | pmid:26277200 |
Kim SA and Rhee MS | Use of caprylic acid to control pathogens (Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium) in apple juice at mild heat temperature. | 2015 | J. Appl. Microbiol. | pmid:26257401 |
Librán-Pérez M et al. | Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid-sensing systems in rainbow trout. | 2015 | Domest. Anim. Endocrinol. | pmid:26226227 |
Upadhyaya I et al. | Reducing Colonization and Eggborne Transmission of Salmonella Enteritidis in Layer Chickens by In-Feed Supplementation of Caprylic Acid. | 2015 | Foodborne Pathog. Dis. | pmid:26135893 |
Hovorková P and Skřivanová E | Use of Caprylic Acid in Broiler Chickens: Effect on Campylobacter jejuni. | 2015 | Foodborne Pathog. Dis. | pmid:26114373 |
Kadota Y et al. | Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. | 2015 | Metab. Clin. Exp. | pmid:26104959 |
De Preter V et al. | Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. | 2015 | Gut | pmid:24811995 |