octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Seyfried TN and Mukherjee P | Targeting energy metabolism in brain cancer: review and hypothesis. | 2005 | Nutr Metab (Lond) | pmid:16242042 |
Wang J et al. | Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers. | 2006 | Peptides | pmid:16242213 |
Hartmann R et al. | Tailor-made olefinic medium-chain-length poly[(R)-3-hydroxyalkanoates] by Pseudomonas putida GPo1: batch versus chemostat production. | 2006 | Biotechnol. Bioeng. | pmid:16255038 |
Sjöbom MB et al. | Binary phase equilibria of three alpha-methyl-substituted sodium alkanoate surfactants. | 2003 | J Colloid Interface Sci | pmid:16256488 |
Shrake A et al. | Thermal stabilization of human albumin by medium- and short-chain n-alkyl fatty acid anions. | 2006 | Biopolymers | pmid:16273515 |
Dutta P and Fendler JH | Preparation of cadmium sulfide nanoparticles in self-reproducing reversed micelles. | 2002 | J Colloid Interface Sci | pmid:16290439 |
pmid:16290581 | ||||
Spildo K and Blokhus AM | Adsorption from the organic phase in the octanoic acid-octylamine-silica system. | 2002 | J Colloid Interface Sci | pmid:16290813 |
pmid:16324890 | ||||
Pepi M et al. | An antarctic psychrotrophic bacterium Halomonas sp. ANT-3b, growing on n-hexadecane, produces a new emulsyfying glycolipid. | 2005 | FEMS Microbiol. Ecol. | pmid:16329937 |
Roncero C and Goodridge AG | Hexanoate and octanoate inhibit transcription of the malic enzyme and fatty acid synthase genes in chick embryo hepatocytes in culture. | 1992 | J. Biol. Chem. | pmid:1634532 |
Hennes MM et al. | Mechanism of free fatty acid effects on hepatocyte insulin receptor binding and processing. | 1993 | Obes. Res. | pmid:16353347 |
pmid:16356474 | ||||
Jambor de Sousa UL et al. | Caprylic acid infusion acts in the liver to decrease food intake in rats. | 2006 | Physiol. Behav. | pmid:16360711 |
Delamarre SC and Batt CA | Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16362422 |
Iram SH and Cronan JE | The beta-oxidation systems of Escherichia coli and Salmonella enterica are not functionally equivalent. | 2006 | J. Bacteriol. | pmid:16385050 |
pmid:16398513 | ||||
pmid:16426704 | ||||
Parkkinen J et al. | A modified caprylic acid method for manufacturing immunoglobulin G from human plasma with high yield and efficient virus clearance. | 2006 | Vox Sang. | pmid:16430667 |
pmid:16437180 | ||||
Perri F et al. | 13C-octanoic acid breath test for measuring gastric emptying of solids. | 2005 Sep-Oct | Eur Rev Med Pharmacol Sci | pmid:16457123 |
Usai Satta P et al. | 13C-octanoic acid breath test in functional and organic disease: critical review of literature. | 2005 Sep-Oct | Eur Rev Med Pharmacol Sci | pmid:16457124 |
Bonazzi P et al. | Gastric emptying and intragastric balloon in obese patients. | 2005 Sep-Oct | Eur Rev Med Pharmacol Sci | pmid:16457125 |
Rossi Z et al. | Electrogastrography. | 2005 Sep-Oct | Eur Rev Med Pharmacol Sci | pmid:16457127 |
pmid:16462014 | ||||
pmid:16466902 | ||||
Bryant P et al. | The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate. | 2006 | Anal. Biochem. | pmid:16500612 |
pmid:16504913 | ||||
Baum G et al. | Clarification of ascites fluid. | 1991 | BioTechniques | pmid:1651092 |
Zhang Z et al. | Thermo-sensitive transition of monomethoxy poly(ethylene glycol)-block-poly(trimethylene carbonate) films to micellar-like nanoparticles. | 2006 | J Control Release | pmid:16516326 |
Hall DR et al. | Identification of components of male-produced pheromone of coffee white stemborer, Xylotrechus quadripes. | 2006 | J. Chem. Ecol. | pmid:16525878 |
Punkkinen J et al. | Measuring gastric emptying: comparison of 13C-octanoic acid breath test and scintigraphy. | 2006 | Dig. Dis. Sci. | pmid:16534667 |
Kasicka-Jonderko A et al. | Short- and medium-term reproducibility of gastric emptying of a solid meal determined by a low dose of 13C-octanoic acid and nondispersive isotope-selective infrared spectrometry. | 2006 | World J. Gastroenterol. | pmid:16534878 |
Wilson TA et al. | Structured triglycerides containing caprylic (8:0) and oleic (18:1) fatty acids reduce blood cholesterol concentrations and aortic cholesterol accumulation in hamsters. | 2006 | Biochim. Biophys. Acta | pmid:16580874 |
Hinson JA and Neal RA | An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase. | 1975 | Biochim. Biophys. Acta | pmid:165828 |
pmid:16602759 | ||||
Conte E et al. | Regulation of polyhydroxyalkanoate synthases (phaC1 and phaC2) gene expression in Pseudomonas corrugata. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16607528 |
Hosoda H et al. | Biological, physiological, and pharmacological aspects of ghrelin. | 2006 | J. Pharmacol. Sci. | pmid:16612045 |
Müller T et al. | Impact of gastric emptying on levodopa pharmacokinetics in Parkinson disease patients. | 2006 Mar-Apr | Clin Neuropharmacol | pmid:16614536 |
Hauser B et al. | Variability of the 13C-octanoic acid breath test for gastric emptying of solids in healthy children. | 2006 | Aliment. Pharmacol. Ther. | pmid:16629936 |
Vikbjerg AF et al. | Comparative evaluation of the emulsifying properties of phosphatidylcholine after enzymatic acyl modification. | 2006 | J. Agric. Food Chem. | pmid:16637690 |
pmid:16637815 | ||||
May JM et al. | Cellular disulfide-reducing capacity: an integrated measure of cell redox capacity. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16650819 |
Vincenzini MT et al. | The Effects of Octanoate and Oleate on Isocitrate Lyase Activity during the Germination of Pinus pinea Seeds. | 1973 | Plant Physiol. | pmid:16658603 |
Kihlberg T et al. | Multiple isotopically labeled fatty acids. 1-11C-2,2',3,3'-tetradeutero palmitic and octanoic acid. | 1991 | Acta Radiol Suppl | pmid:1666733 |
Waldenström A et al. | Myocardial disposition of [1-11C]palmitic acid, 2,2',3,3'-tetradeuteropalmitic acid and octanoic acid in the pig. | 1991 | Acta Radiol Suppl | pmid:1666752 |
Iimura S and Iwahashi H | Enhancement by cigarette smoke extract of the radical formation in a reaction mixture of 13-hydroperoxide octadecadienoic acid and ferric ions. | 2006 | J. Biochem. | pmid:16672267 |
Gasbarrini G et al. | Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation. | 2006 | World J. Gastroenterol. | pmid:16688801 |
Otero R et al. | Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia. | 2006 | Trans. R. Soc. Trop. Med. Hyg. | pmid:16698053 |
pmid:16699854 | ||||
Kachi M et al. | Effects of Helicobacter pylori eradication therapy on gastric emptying measured using the 13C-octanoic acid breath test and the acetaminophen method. | 2006 | J. Gastroenterol. Hepatol. | pmid:16704530 |
Bouvet L et al. | Erythromycin promotes gastric emptying during acute pain in volunteers. | 2006 | Anesth. Analg. | pmid:16717329 |
Vanden Heuvel JP et al. | Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. | 2006 | Toxicol. Sci. | pmid:16731579 |
Jones PM et al. | Medium-chain fatty acids undergo elongation before beta-oxidation in fibroblasts. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16750167 |
Matulka RA et al. | Safety evaluation of a medium- and long-chain triacylglycerol oil produced from medium-chain triacylglycerols and edible vegetable oil. | 2006 | Food Chem. Toxicol. | pmid:16753249 |
Samant MP et al. | Novel analogues of degarelix incorporating hydroxy-, methoxy-, and pegylated-urea moieties at positions 3, 5, 6 and the N-terminus. Part III. | 2006 | J. Med. Chem. | pmid:16759096 |
Gerhardt WW et al. | Functional lactide monomers: methodology and polymerization. | 2006 | Biomacromolecules | pmid:16768392 |
pmid:16771408 | ||||
Nicholson CE et al. | Unique crystal morphologies of glycine grown from octanoic acid-in-water emulsions. | 2006 | J. Am. Chem. Soc. | pmid:16771468 |
Oshino N et al. | The properties of hydrogen peroxide production under hyperoxic and hypoxic conditions of perfused rat liver. | 1975 | Biochem. J. | pmid:167718 |
Crawford MJ et al. | Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast. | 2006 | EMBO J. | pmid:16778769 |
pmid:16787034 | ||||
Martin JD et al. | Structure and membrane affinity of new amphiphilic siderophores produced by Ochrobactrum sp. SP18. | 2006 | J. Biol. Inorg. Chem. | pmid:16791646 |
Brill J et al. | Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami. | 2006 | J. Neurosci. | pmid:16793888 |
Bjorge SM and Baillie TA | Studies on the beta-oxidation of valproic acid in rat liver mitochondrial preparations. | 1991 Jul-Aug | Drug Metab. Dispos. | pmid:1680661 |
Kim BH and Akoh CC | Characteristics of structured lipid prepared by lipase-catalyzed acidolysis of roasted sesame oil and caprylic acid in a bench-scale continuous packed bed reactor. | 2006 | J. Agric. Food Chem. | pmid:16819927 |
Hung HM et al. | Products and mechanisms of the reaction of oleic acid with ozone and nitrate radical. | 2005 | J Phys Chem A | pmid:16833788 |
Thorburn MS et al. | Attenuated gastric distress but no benefit to performance with adaptation to octanoate-rich esterified oils in well-trained male cyclists. | 2006 | J. Appl. Physiol. | pmid:16840580 |
Kandare E and Hossenlopp JM | Hydroxy double salt anion exchange kinetics: effects of precursor structure and anion size. | 2005 | J Phys Chem B | pmid:16851994 |
Guo W et al. | Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species. | 2006 | Nutr Metab (Lond) | pmid:16872526 |
pmid:16889392 | ||||
Iwahashi H et al. | High performance liquid chromatography/electron spin resonance/mass spectrometry analyses of radicals formed in an anaerobic reaction of 9- (or 13-) hydroperoxide octadecadienoic acids with ferrous ions. | 2006 | J Chromatogr A | pmid:16889785 |
Jambor de Sousa UL et al. | Hepatic-portal oleic acid inhibits feeding more potently than hepatic-portal caprylic acid in rats. | 2006 | Physiol. Behav. | pmid:16890966 |
Ballard JM et al. | Degradation of vitamin D3 in a stressed formulation: the identification of esters of vitamin D3 formed by a transesterification with triglycerides. | 2007 | J Pharm Biomed Anal | pmid:16901672 |
Vinson SB et al. | Nest liquid resources of several cavity nesting bees in the genus Centris and the identification of a preservative, levulinic acid. | 2006 | J. Chem. Ecol. | pmid:16902822 |
Jiang Y et al. | The soluble acyl-acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family. | 2006 | Biochemistry | pmid:16906759 |
Ho IC et al. | Structure and polymer form of poly-3-hydroxyalkanoates produced by Pseudomonas oleovorans grown with mixture of sodium octanoate/undecylenic acid and sodium octanoate/5-phenylvaleric acid. | 2007 | Int. J. Biol. Macromol. | pmid:16919325 |
Allard MF et al. | AMPK and metabolic adaptation by the heart to pressure overload. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16920812 |
Gil-Campos M et al. | Ghrelin: a hormone regulating food intake and energy homeostasis. | 2006 | Br. J. Nutr. | pmid:16923214 |
Sanaka M et al. | Assessment of the gastric emptying velocity by the 13C-octanoate breath test: deconvolution versus a Wagner-Nelson analysis. | 2006 | J. Gastroenterol. | pmid:16933000 |
Nohara S et al. | Gastric emptying in patients with Type 2 diabetes mellitus and diabetes associated with mitochondrial DNA 3243 mutation using 13C-octanoic acid breath test. | 2006 Sep-Oct | J. Diabetes Complicat. | pmid:16949516 |
Elluru S et al. | Comparative study of the anti-inflammatory effect of two intravenous immunoglobulin preparations manufactured by different processes. | 2006 | Immunol. Lett. | pmid:16952403 |
Kragh-Hansen U et al. | Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis. | 2006 | J. Mol. Biol. | pmid:16979183 |
Redwan el-RM | Comparison between therapeutic antitoxin F(ab)2 fractionated with ammonium sulfate and caprylic acid. | 2006 | J Immunoassay Immunochem | pmid:16981645 |
Tack J et al. | Influence of delaying gastric emptying on meal-related symptoms in healthy subjects. | 2006 | Aliment. Pharmacol. Ther. | pmid:16984498 |
Amalaradjou MA et al. | Inactivation of escherichia coli O157:H7 in cattle drinking water by sodium caprylate. | 2006 | J. Food Prot. | pmid:16995532 |
PuigmartÃ-Luis J et al. | Noncovalent control for bottom-up assembly of functional supramolecular wires. | 2006 | J. Am. Chem. Soc. | pmid:17002326 |
Darnell ME and Taylor DR | Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. | 2006 | Transfusion | pmid:17002634 |
Tao F et al. | Competition and coadsorption of di-acids and carboxylic acid solvents on HOPG. | 2006 | J Phys Chem B | pmid:17004820 |
Foschi D et al. | Treatment of morbid obesity by intraparietogastric administration of botulinum toxin: a randomized, double-blind, controlled study. | 2007 | Int J Obes (Lond) | pmid:17006442 |
Ayub ND et al. | Impaired polyhydroxybutyrate biosynthesis from glucose in Pseudomonas sp. 14-3 is due to a defective beta-ketothiolase gene. | 2006 | FEMS Microbiol. Lett. | pmid:17020558 |
Sun X et al. | Beta-subunit-dependent modulation of hSlo BK current by arachidonic acid. | 2007 | J. Neurophysiol. | pmid:17021030 |
Moechars D et al. | Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. | 2006 | Gastroenterology | pmid:17030183 |
Aydin HM et al. | Attachment and growth of fibroblasts on poly(L-lactide/epsilon-caprolactone) scaffolds prepared in supercritical CO2 and modified by polyethylene imine grafting with ethylene diamine-plasma in a glow-discharge apparatus. | 2006 | Int J Artif Organs | pmid:17033995 |
Battiprolu PK et al. | Sex differences in energy metabolism and performance of teleost cardiac tissue. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17038442 |
Hu F and You S | Inactivation of type I polyhydroxyalkanoate synthase in Aeromonas hydrophila resulted in discovery of another potential PHA synthase. | 2007 | J. Ind. Microbiol. Biotechnol. | pmid:17043804 |
Anraku M et al. | The role of N-acetyl-methioninate as a new stabilizer for albumin products. | 2007 | Int J Pharm | pmid:17045433 |
Farrer BT et al. | Quantitation of crystalline material within a liquid vehicle using 1H/19F CP/MAS NMR. | 2007 | J Pharm Sci | pmid:17051585 |
Chua BY et al. | Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups. | 2007 | Vaccine | pmid:17055123 |
Grill V et al. | Multiple abnormalities in insulin responses to nonglucose nutrients in neonatally streptozotocin diabetic rats. | 1991 | Endocrinology | pmid:1706269 |