octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Schulz S et al. | Biological activity of volatiles from marine and terrestrial bacteria. | 2010 | Mar Drugs | pmid:21339960 |
Franta Z et al. | Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. | 2010 | Parasit Vectors | pmid:21156061 |
Gumus S et al. | The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema - an experimental study. | 2010 | Arch Med Sci | pmid:22427756 |
Lian B et al. | Identification and characterization of duck plague virus glycoprotein C gene and gene product. | 2010 | Virol. J. | pmid:21110887 |
Fang X et al. | Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. | 2010 | BMC Syst Biol | pmid:21092312 |
Little TJ and Feinle-Bisset C | Oral and gastrointestinal sensing of dietary fat and appetite regulation in humans: modification by diet and obesity. | 2010 | Front Neurosci | pmid:21088697 |
JunGang L et al. | Cloning and biochemical characterization of a novel lipolytic gene from activated sludge metagenome, and its gene product. | 2010 | Microb. Cell Fact. | pmid:21054894 |
Ruppender NS et al. | Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells. | 2010 | PLoS ONE | pmid:21085597 |
Xu W et al. | Odorant-binding proteins of the malaria mosquito Anopheles funestus sensu stricto. | 2010 | PLoS ONE | pmid:21042539 |
Casewell NR et al. | Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom. | 2010 | PLoS Negl Trop Dis | pmid:21049058 |
Bao F et al. | New cobalt-mediated radical polymerization (CMRP) of methyl methacrylate initiated by two single-component dinuclear β-diketone cobalt (II) catalysts. | 2010 | PLoS ONE | pmid:21049027 |
Kundu S and Roy D | Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. | 2010 | Bioinformation | pmid:20978606 |
Guo J et al. | Characterization of a novel esterase Rv0045c from Mycobacterium tuberculosis. | 2010 | PLoS ONE | pmid:20957207 |
Ren Q et al. | Influence of growth stage on activities of polyhydroxyalkanoate (PHA) polymerase and PHA depolymerase in Pseudomonas putida U. | 2010 | BMC Microbiol. | pmid:20937103 |
Dessein AF et al. | A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report. | 2010 | Orphanet J Rare Dis | pmid:20923556 |
Pepin E et al. | Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells. | 2010 | J Diabetes | pmid:20923481 |
Kemik O et al. | The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. | 2010 | World J Surg Oncol | pmid:20920199 |
Tesfaye S et al. | Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. | 2010 | Diabetes Care | pmid:20876709 |
Zea L et al. | Chromatography-olfactometry study of the aroma of fino sherry wines. | 2010 | Int J Anal Chem | pmid:20689702 |
German JB and Dillard CJ | Saturated fats: a perspective from lactation and milk composition. | 2010 | Lipids | pmid:20652757 |
Koizumi M et al. | Reconstruction-dependent recovery from anorexia and time-related recovery of regulatory ghrelin system in gastrectomized rats. | 2010 | Int J Pept | pmid:20721337 |
Pulkkinen L et al. | Ghrelin in diabetes and metabolic syndrome. | 2010 | Int J Pept | pmid:20700400 |
Schwandt SE et al. | Differential roles for octanoylated and decanoylated ghrelins in regulating appetite and metabolism. | 2010 | Int J Pept | pmid:20700399 |
Wang Y et al. | 5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice. | 2010 | BMC Cancer | pmid:20678220 |
White AP et al. | A global metabolic shift is linked to Salmonella multicellular development. | 2010 | PLoS ONE | pmid:20676398 |
Abubakar IS et al. | Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria. | 2010 | PLoS Negl Trop Dis | pmid:20668549 |
Legrand P and Rioux V | The complex and important cellular and metabolic functions of saturated fatty acids. | 2010 | Lipids | pmid:20625935 |
Grossauer J et al. | The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine. | 2010 | Bioorg. Med. Chem. | pmid:20621491 |
Ma Y et al. | Nanoparticles of Poly(Lactide-Co-Glycolide)-d-a-Tocopheryl Polyethylene Glycol 1000 Succinate Random Copolymer for Cancer Treatment. | 2010 | Nanoscale Res Lett | pmid:20596457 |
Buglino JA and Resh MD | Identification of conserved regions and residues within Hedgehog acyltransferase critical for palmitoylation of Sonic Hedgehog. | 2010 | PLoS ONE | pmid:20585641 |
O'Bryan G et al. | Stress sensing in polycaprolactone films via an embedded photochromic compound. | 2010 | ACS Appl Mater Interfaces | pmid:20568704 |
Satou M et al. | Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. | 2010 | Endocrinology | pmid:20685872 |
Jordan SD et al. | Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis. | 2010 | Cell. Mol. Life Sci. | pmid:20549539 |
Falamarzian A and Lavasanifar A | Optimization of the hydrophobic domain in poly(ethylene oxide)-poly(varepsilon-caprolactone) based nano-carriers for the solubilization and delivery of Amphotericin B. | 2010 | Colloids Surf B Biointerfaces | pmid:20674292 |
Tsuji M et al. | Higher toxicity of dibutyltin and poly-L-lactide with a large amount of tin but lower toxicity of poly-L-lactide of synthetic artificial dura mater exhibited on murine astrocyte cell line. | 2010 | Yakugaku Zasshi | pmid:20519863 |
Shahmoradi B et al. | Modification of neodymium-doped ZnO hybrid nanoparticles under mild hydrothermal conditions. | 2010 | Nanoscale | pmid:20648343 |
Anzai N et al. | Molecular mechanism of ochratoxin a transport in the kidney. | 2010 | Toxins (Basel) | pmid:22069643 |
Karakatsani M et al. | The effect of permeation enhancers on the viscosity and the release profile of transdermal hydroxypropyl methylcellulose gel formulations containing diltiazem HCl. | 2010 | Drug Dev Ind Pharm | pmid:20545504 |
Cao J et al. | Synthesis of a novel biodegradable polyurethane with phosphatidylcholines. | 2010 | Int J Mol Sci | pmid:20480047 |
Sobczak M | Synthesis and characterization of polyester conjugates of ciprofloxacin. | 2010 | Eur J Med Chem | pmid:20541292 |
Hartmann R et al. | Simultaneous biosynthesis of two copolymers in Pseudomonas putida GPo1 using a two-stage continuous culture system. | 2010 | Biomacromolecules | pmid:20459087 |
Clegg ME and Shafat A | Procedures in the 13C octanoic acid breath test for measurement of gastric emptying: analysis using Bland-Altman methods. | 2010 | Scand. J. Gastroenterol. | pmid:20443742 |
Ida T et al. | Purification and characterization of caprine ghrelin and its effect on growth hormone release. | 2010 | J. Mol. Neurosci. | pmid:20437258 |
Oh KS et al. | Temperature-induced gel formation of core/shell nanoparticles for the regeneration of ischemic heart. | 2010 | J Control Release | pmid:20417673 |
Endo M et al. | In vitro probe acylcarnitine profiling assay using cultured fibroblasts and electrospray ionization tandem mass spectrometry predicts severity of patients with glutaric aciduria type 2. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:20392676 |
Mohanty AK et al. | Etoposide-loaded biodegradable amphiphilic methoxy (poly ethylene glycol) and poly (epsilon caprolactone) copolymeric micelles as drug delivery vehicle for cancer therapy. | 2010 | Drug Deliv | pmid:20370380 |
Desjardins CA et al. | The genetic basis of interspecies host preference differences in the model parasitoid Nasonia. | 2010 | Heredity (Edinb) | pmid:20087393 |
Kobayashi M et al. | Retarding activity of 6-O-acyl-D-alloses against plant growth. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20057117 |
Comar JF et al. | Hepatic zonation of carbon and nitrogen fluxes derived from glutamine and ammonia transformations. | 2010 | J. Biomed. Sci. | pmid:20055990 |
Nikolic L et al. | Novel microwave-assisted synthesis of poly(D,L-lactide): the influence of monomer/initiator molar ratio on the product properties. | 2010 | Sensors (Basel) | pmid:22399924 |
Antúnez J et al. | Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities. | 2010 | J Venom Res | pmid:21544177 |
Messens W et al. | Inhibition of Salmonella typhimurium by medium-chain fatty acids in an in vitro simulation of the porcine cecum. | 2010 | Vet. Microbiol. | pmid:19709819 |
Zhu L et al. | Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20644917 |
Guo YJ et al. | Inhibitory effects of fatty acids on the activity of mushroom tyrosinase. | 2010 | Appl. Biochem. Biotechnol. | pmid:20544305 |
Cometto-Muñiz JE and Abraham MH | Structure-activity relationships on the odor detectability of homologous carboxylic acids by humans. | 2010 | Exp Brain Res | pmid:20931179 |
Coll C et al. | Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports. | 2010 | Chemistry | pmid:20645326 |
Okumu FO et al. | Development and field evaluation of a synthetic mosquito lure that is more attractive than humans. | 2010 | PLoS ONE | pmid:20126628 |
Olanga EA et al. | Attraction of Anopheles gambiae to odour baits augmented with heat and moisture. | 2010 | Malar. J. | pmid:20051143 |
Azulay DO et al. | Stochastic simulations of the exponential-beta function as an assessment of the validity of the choice of the Wagner-Nelson method for the analysis of ¹³C-octanoic acid breath tests. | 2010 | J Breath Res | pmid:21383478 |
Chang SS et al. | Inactivation of Escherichia coli O157:H7 and Salmonella spp. on alfalfa seeds by caprylic acid and monocaprylin. | 2010 | Int. J. Food Microbiol. | pmid:20926150 |
Murzyn A et al. | Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. | 2010 | PLoS ONE | pmid:20706577 |
Patel SK et al. | Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. | 2010 | Biomaterials | pmid:19796808 |
Nebbioso A et al. | Limitations of electrospray ionization in the analysis of a heterogeneous mixture of naturally occurring hydrophilic and hydrophobic compounds. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20941764 |
Kato T et al. | Short- and medium-chain fatty acids enhance the cell surface expression and transport capacity of the bile salt export pump (BSEP/ABCB11). | 2010 | Biochim. Biophys. Acta | pmid:20398791 |
Jian J et al. | Metabolic engineering for microbial production of polyhydroxyalkanoates consisting of high 3-hydroxyhexanoate content by recombinant Aeromonas hydrophila. | 2010 | Bioresour. Technol. | pmid:20236821 |
Qualls-Creekmore E et al. | Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. | 2010 | Neurogastroenterol. Motil. | pmid:19566592 |
Mills JK et al. | The effects of feeding medium-chain triglycerides on the growth, insulin responsiveness, and body composition of Holstein calves from birth to 85 kg of body weight. | 2010 | J. Dairy Sci. | pmid:20723699 |
Yuan JS et al. | Effect of surfactant concentration on transdermal lidocaine delivery with linker microemulsions. | 2010 | Int J Pharm | pmid:20363304 |
Blanco E et al. | Effect of alkyl chain asymmetry on catanionic mixtures of hydrogenated and fluorinated surfactants. | 2010 | J Colloid Interface Sci | pmid:19853859 |
Ma J et al. | Effects of cefaclor on gastric emptying and cholecystokinin release in healthy humans. | 2010 | Regul. Pept. | pmid:19914303 |
Athavale M et al. | Validation of a simple, rapid and cost effective method for the estimation of caprylic acid and sodium caprylate from biological products using NEFA-C kit. | 2010 | Biologicals | pmid:19919899 |
Grodzki AC and Berenstein E | Antibody purification: ammonium sulfate fractionation or gel filtration. | 2010 | Methods Mol. Biol. | pmid:20012814 |
Ishima Y et al. | One-step preparation of S-nitrosated human serum albumin with high biological activities. | 2010 | Nitric Oxide | pmid:20451647 |
Grattagliano I et al. | 13C-breath tests for clinical investigation of liver mitochondrial function. | 2010 | Eur. J. Clin. Invest. | pmid:20597965 |
Oztürk T et al. | Production of medium-chain triacylglycerols from corn oil: optimization by response surface methodology. | 2010 | Bioresour. Technol. | pmid:20576567 |
Liu Y and Nair MG | An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. | 2010 | J. Nat. Prod. | pmid:20565070 |
Bayer S et al. | Indication for a new lipolytic enzyme family: isolation and characterization of two esterases from a metagenomic library. | 2010 | J. Mol. Microbiol. Biotechnol. | pmid:20530969 |
Sallam HS et al. | Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20427716 |
Magliano P et al. | Repercussion of a deficiency in mitochondrial ß-oxidation on the carbon flux of short-chain fatty acids to the peroxisomal ß-oxidation cycle in Aspergillus nidulans. | 2010 | Biochim. Biophys. Acta | pmid:20736083 |
Perri F et al. | (13)C-octanoic acid breath test (OBT) with a new test meal (EXPIROGer): Toward standardization for testing gastric emptying of solids. | 2010 | Dig Liver Dis | pmid:20116352 |
Skrivanová E et al. | Changes in the bacterial population of the caecum and stomach of the rabbit in response to addition of dietary caprylic acid. | 2010 | Vet. Microbiol. | pmid:20181443 |
SolÃs de los Santos F et al. | Caprylic Acid reduces enteric campylobacter colonization in market-aged broiler chickens but does not appear to alter cecal microbial populations. | 2010 | J. Food Prot. | pmid:20132669 |
O'Brien M et al. | Ghrelin in the human myometrium. | 2010 | Reprod. Biol. Endocrinol. | pmid:20509935 |
Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |
Fernández GP et al. | Neutralization of Bothrops mattogrossensis snake venom from Bolivia: experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation. | 2010 Feb-Mar | Toxicon | pmid:19647761 |
Stavarachi M et al. | Spinal muscular atrophy disease: a literature review for therapeutic strategies. | 2010 Jan-Mar | J Med Life | pmid:20302191 |
Sun K et al. | Rhodium-catalyzed synthesis of 2,3-disubstituted indoles from β,β-disubstituted stryryl azides. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21308937 |
Zakaria ZA et al. | Hepatoprotective activity of dried- and fermented-processed virgin coconut oil. | 2011 | Evid Based Complement Alternat Med | pmid:21318140 |
Kwon MA et al. | Synthesis activity-based zymography for detection of lipases and esterases. | 2011 | Biotechnol. Lett. | pmid:21120585 |
Klukowska A et al. | Low incidence of factor VIII inhibitors in previously untreated patients during prophylaxis, on-demand treatment and surgical procedures, with Octanate®: interim report from an ongoing prospective clinical study. | 2011 | Haemophilia | pmid:21118334 |
Waltenberger B et al. | Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine. | 2011 | Phytomedicine | pmid:20851587 |
González-Mas MC et al. | Comparative analysis of the volatile fraction of fruit juice from different Citrus species. | 2011 | PLoS ONE | pmid:21818287 |
Huang CB et al. | Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. | 2011 | Arch. Oral Biol. | pmid:21333271 |
Hassan N et al. | Rheological properties of ovalbumin hydrogels as affected by surfactants addition. | 2011 | Int. J. Biol. Macromol. | pmid:21262258 |
Ma Y et al. | Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment. | 2011 | Int J Nanomedicine | pmid:22114498 |
Stepanenko IN et al. | Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells. | 2011 | Inorg Chem | pmid:22111668 |
Bluck LJ et al. | Bayesian hierarchical methods to interpret the (13)C-octanoic acid breath test for gastric emptying. | 2011 | Digestion | pmid:21042021 |
El Abd YS et al. | Neutralizing activities of caprine antibodies towards conserved regions of the HCV envelope glycoprotein E2. | 2011 | Virol. J. | pmid:21819575 |
Chen R et al. | Chemiluminescent nanomicelles for imaging hydrogen peroxide and self-therapy in photodynamic therapy. | 2011 | J. Biomed. Biotechnol. | pmid:21765637 |
Lawo NC et al. | The volatile metabolome of grapevine roots: first insights into the metabolic response upon phylloxera attack. | 2011 | Plant Physiol. Biochem. | pmid:21764593 |