octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with octanoic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pi-Sunyer FX | Effect of long- and medium-chain fatty acids on insulin secretion from pieces of rat pancreas. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1144459 |
Paquet RJ et al. | Effects of thiamine deficiency and octanoate administration, in vivo, on gluconeogenesis in rat kidney slices and on amino acid profile in rat liver. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5039394 |
Morrow RJ et al. | Functional utilization of palmitate, octanoate, and glucose by the isolated rat heart. | 1973 | Proc. Soc. Exp. Biol. Med. | pmid:4683244 |
Maragoudakis ME et al. | Metabolism of octanoate and its effect on glucose and palmitate utilization by isolated fat cells. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:236573 |
McDonough KH and Spitzer JJ | Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. | 1983 | Proc. Soc. Exp. Biol. Med. | pmid:6412237 |
Pösö AR and Mortimore GE | Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6589593 |
Jenkins DL and Griffith OW | Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3455765 |
Gutierrez JA et al. | Ghrelin octanoylation mediated by an orphan lipid transferase. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18443287 |
Merritt ME et al. | Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18056642 |
Omura T | Recollection of the early years of the research on cytochrome P450. | 2011 | Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. | pmid:22156409 |