octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Nudel BC et al. Optimization by factorial analysis of caprylic acid precipitation of non-immunoglobulins from hyperimmune equine plasma for antivenom preparation. 2012 Toxicon pmid:22079738
Brun AC et al. The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. 2012 Clin Nutr pmid:21835514
Ademola-Majekodunmi FO et al. Incidence of snakebites in Kaltungo, Gombe State and the efficacy of a new highly purified monovalent antivenom in treating snakebite patients from January 2009 to December 2010. 2012 Bull Soc Pathol Exot pmid:22851309
Sharma PK et al. Kinetics of medium-chain-length polyhydroxyalkanoate production by a novel isolate of Pseudomonas putida LS46. 2012 Can. J. Microbiol. pmid:22804681
Hämmerle SP et al. The single dose pharmacokinetic profile of a novel oral human parathyroid hormone formulation in healthy postmenopausal women. 2012 Bone pmid:22289659
Rodríguez A et al. Synthesis of 2-monoacylglycerols and structured triacylglycerols rich in polyunsaturated fatty acids by enzyme catalyzed reactions. 2012 Enzyme Microb. Technol. pmid:22759534
Simon-Colin C et al. Development of a three-steps derivatization assay for the localization of double bond in monounsaturated monomers of poly-beta-hydroxyalkanoates by GC-MS. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22717557
Moschonas G et al. Antimicrobials for reduction of Salmonella contamination in uncooked, surface-browned breaded chicken products. 2012 J. Food Prot. pmid:22691468
Cheng Y et al. Thermally controlled release of anticancer drug from self-assembled γ-substituted amphiphilic poly(ε-caprolactone) micellar nanoparticles. 2012 Biomacromolecules pmid:22681332
Vargas M et al. Purification of IgG and albumin from human plasma by aqueous two phase system fractionation. 2012 Biotechnol. Prog. pmid:22619188
Barnette D et al. Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process. 2012 Biologicals pmid:22579294
Fernández J et al. Synthesis, structure and properties of poly(L-lactide-co-ε-caprolactone) statistical copolymers. 2012 J Mech Behav Biomed Mater pmid:22498288
Lockman KA et al. Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. 2012 Liver Int. pmid:22429485
Cordes AA et al. Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. 2012 J Pharm Sci pmid:22422106
Calandra P et al. Emerging dynamics in surfactant-based liquid mixtures: octanoic acid/bis(2-ethylhexyl) amine systems. 2012 J Chem Phys pmid:22360203
Yahashi S et al. GHRP-6 mimics ghrelin-induced stimulation of food intake and suppression of locomotor activity in goldfish. 2012 Peptides pmid:22349352
Tan CH et al. Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. 2012 Acta Trop. pmid:22322247
Ryu JK and Yoo SD Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. 2012 Drug Dev Ind Pharm pmid:22283588
Maricic MJ Oral calcitonin. 2012 Curr Osteoporos Rep pmid:22281725
Tahir MN et al. Stability of lipase immobilized on O-pentynyl dextran. 2012 Bioprocess Biosyst Eng pmid:21932061
Holstein MA et al. Mobile phase modifier effects in multimodal cation exchange chromatography. 2012 Biotechnol. Bioeng. pmid:21898370
Harada E et al. Functional evolution of duplicated odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. 2012 PLoS ONE pmid:22238638
Molinas A et al. Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. 2012 PLoS ONE pmid:22563480
Pereira RF et al. What drives the precipitation of long-chain calcium carboxylates (soaps) in aqueous solution? 2012 Phys Chem Chem Phys pmid:22513819
Rucinski M et al. Evidence suggesting that ghrelin O-acyl transferase inhibitor acts at the hypothalamus to inhibit hypothalamo-pituitary-adrenocortical axis function in the rat. 2012 Peptides pmid:22543218
Can Güven S and Laska M Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. 2012 PLoS ONE pmid:22479594
Takahashi M et al. [Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitro and its therapeutic efficacy in murine oral candidiasis]. 2012 Med Mycol J pmid:23257726
Vazquez-Cruz MA et al. Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans). 2012 J. Food Sci. pmid:22429085
Kuribayashi T et al. Analysis of free fatty acids in sake by an enzymatic method and its application for estimating ethyl caproate and selecting yeast with high productivity of the ester. 2012 Biosci. Biotechnol. Biochem. pmid:22313771
Wan HD et al. Nonthermal effect of microwave irradiation in nonaqueous enzymatic esterification. 2012 Appl. Biochem. Biotechnol. pmid:22262019
Wagner AE et al. A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells. 2012 Oxid Med Cell Longev pmid:22655115
Le Meur S et al. Production of medium-chain-length polyhydroxyalkanoates by sequential feeding of xylose and octanoic acid in engineered Pseudomonas putida KT2440. 2012 BMC Biotechnol. pmid:22913372
Gutierrez JA et al. From ghrelin to ghrelin's O-acyl transferase. 2012 Meth. Enzymol. pmid:22975051
Ohgusu H et al. Enzymatic characterization of GOAT, ghrelin O-acyltransferase. 2012 Meth. Enzymol. pmid:22975052
Matsumoto N and Nakazato M Clinical application of ghrelin for chronic respiratory diseases. 2012 Meth. Enzymol. pmid:22975067
Simon-Colin C et al. Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. 2012 Int. J. Biol. Macromol. pmid:22947450
Ogungbenro K and Aarons L A semi-mechanistic gastric emptying pharmacokinetic model for (13)C-octanoic acid: an evaluation using simulation. 2012 Eur J Pharm Sci pmid:22155547
Otero-Patiño R et al. Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. 2012 Toxicon pmid:22146491
Wlaź P et al. Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice. 2012 Neuropharmacology pmid:22210332
Morrill KM et al. Estimate of colostral immunoglobulin G concentration using refractometry without or with caprylic acid fractionation. 2012 J. Dairy Sci. pmid:22720953
Janssen S et al. Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. 2012 PLoS ONE pmid:22768248
Kovalchuk NM et al. Ionic strength and pH as control parameters for spontaneous surface oscillations. 2012 Langmuir pmid:22480181
Lindenkamp N et al. Genetically modified strains of Ralstonia eutropha H16 with β-ketothiolase gene deletions for production of copolyesters with defined 3-hydroxyvaleric acid contents. 2012 Appl. Environ. Microbiol. pmid:22636005
Hu JY et al. Residue determination and dissipation of ioxynil octanoate in maize and soil. 2012 J Environ Sci Health B pmid:22424062
Lipik VT and Abadie MJ Synthesis of Block Copolymers of Varying Architecture Through Suppression of Transesterification during Coordinated Anionic Ring Opening Polymerization. 2012 Int J Biomater pmid:22844286
Librán-Pérez M et al. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. 2012 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:22496361
Li D et al. In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers. 2012 Int J Nanomedicine pmid:22701317
Zhang JH et al. High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction. 2012 Enzyme Microb. Technol. pmid:22500900
Brown NI Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. 2012 PLoS Negl Trop Dis pmid:22679521
Hasson SS et al. Neutralisation of Local Haemorrhage Induced by the Saw-Scaled Viper Echis carinatus sochureki Venom Using Ethanolic Extract of Hibiscus aethiopicus L. 2012 Evid Based Complement Alternat Med pmid:22666294
Meyer H et al. Lipidic nanocapsule drug delivery: neuronal protection for cochlear implant optimization. 2012 Int J Nanomedicine pmid:22654517
Liberato MV et al. Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and pan-PPAR partial agonists. 2012 PLoS ONE pmid:22649490
Becerra-Dórame MJ et al. Production response and digestive enzymatic activity of the Pacific white shrimp Litopenaeus vannamei (Boone, 1931) intensively pregrown in microbial heterotrophic and autotrophic-based systems. 2012 ScientificWorldJournal pmid:22649317
Shi S et al. Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro. 2012 Int J Nanomedicine pmid:22619525
Abdolmohammadi S et al. Enhancement of mechanical and thermal properties of polycaprolactone/chitosan blend by calcium carbonate nanoparticles. 2012 Int J Mol Sci pmid:22605993
Kube M et al. Current view on phytoplasma genomes and encoded metabolism. 2012 ScientificWorldJournal pmid:22550465
Wood P Human normal immunoglobulin in the treatment of primary immunodeficiency diseases. 2012 Ther Clin Risk Manag pmid:22547934
Li J et al. Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts. 2012 PLoS ONE pmid:22529899
Kim JW Could carbon breath test measurement accurately reflect gastric emptying of liquid nutrient meal in the critically ill patients? (Gut 2011;60:1336-1343). 2012 J Neurogastroenterol Motil pmid:22523735
Delporte C Recent advances in potential clinical application of ghrelin in obesity. 2012 J Obes pmid:22523666
Park S et al. Development of sandwich enzyme-linked immunosorbent assay for the detection of Cronobacter muytjensii (formerly called Enterobacter sakazakii). 2012 Microbiol. Immunol. pmid:22519814
Su Z et al. Rates of fatty acid oxidations by P450 compound I are pH dependent. 2012 Chembiochem pmid:22890798
Liang QH et al. Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway. 2012 PLoS ONE pmid:22514603
Jiang X et al. Biosynthesis and properties of medium-chain-length polyhydroxyalkanoates with enriched content of the dominant monomer. 2012 Biomacromolecules pmid:22871146
Lin HV et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. 2012 PLoS ONE pmid:22506074
Akbarzadeh A et al. Preparation and in vitro evaluation of doxorubicin-loaded Fe₃O₄ magnetic nanoparticles modified with biocompatible copolymers. 2012 Int J Nanomedicine pmid:22334781
Du J et al. Biodegradable nanoparticles of mPEG-PLGA-PLL triblock copolymers as novel non-viral vectors for improving siRNA delivery and gene silencing. 2012 Int J Mol Sci pmid:22312268
Ling B et al. D-Lactate altered mitochondrial energy production in rat brain and heart but not liver. 2012 Nutr Metab (Lond) pmid:22296683
Monteagudo E et al. Development, characterization, and in vitro evaluation of tamoxifen microemulsions. 2012 J Drug Deliv pmid:22272375
Aissa I et al. Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities. 2012 Lipids Health Dis pmid:22264330
Lu J et al. A molecular mechanism for modulating plasma Zn speciation by fatty acids. 2012 J. Am. Chem. Soc. pmid:22239162
Andersen JT et al. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. 2012 Nat Commun pmid:22215085
Yamada M et al. A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. 2012 Sci Rep pmid:23226596
Maletínská L et al. Characterization of new stable ghrelin analogs with prolonged orexigenic potency. 2012 J. Pharmacol. Exp. Ther. pmid:22182933
Riniker S et al. Temperature dependence of the dielectric permittivity of acetic acid, propionic acid and their methyl esters: a molecular dynamics simulation study. 2012 Chemphyschem pmid:22383366
Faria M et al. Surface Characterization of Asymmetric Bi-Soft Segment Poly(ester urethane urea) Membranes for Blood-Oxygenation Medical Devices. 2012 Int J Biomater pmid:22164163
Layek B and Singh J N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. 2012 Carbohydr Polym pmid:24750737
Goh YS and Tan IK Polyhydroxyalkanoate production by antarctic soil bacteria isolated from Casey Station and Signy Island. 2012 Microbiol. Res. pmid:21945102
Chang P et al. The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. 2012 Dis Model Mech pmid:21876211
Eren E et al. Substrate specificity within a family of outer membrane carboxylate channels. 2012 PLoS Biol. pmid:22272184
Nanjwade BK et al. Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. 2011 Oct-Dec Sci Pharm pmid:22145101
Hines JD et al. Inappropriate use of D-values for determining biocidal activity of various antimicrobials. 2011 Jan-Feb J. Food Sci. pmid:21535698
Ron Y et al. Early satiety is the only patient-reported symptom associated with delayed gastric emptying, as assessed by breath-test. 2011 J Neurogastroenterol Motil pmid:21369493
Schiavon FP et al. Paradoxical increase in liver ketogenesis during long-term insulin-induced hypoglycemia in diabetic rats. 2011 Exp. Biol. Med. (Maywood) pmid:21321320
Tong LH et al. Pentasubstituted ferrocene and dirhodium(II) tetracarboxylate as building blocks for discrete fullerene-like and extended supramolecular structures. 2011 Inorg Chem pmid:21314191
Ou W et al. Biodegradable block poly(ester-urethane)s based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymers. 2011 Biomaterials pmid:21310479
Meng Y et al. Role of counteranions in polymeric ionic liquid-based solid-phase microextraction coatings for the selective extraction of polar compounds. 2011 Anal. Chim. Acta pmid:21277416
Pérez D et al. A novel halophilic lipase, LipBL, showing high efficiency in the production of eicosapentaenoic acid (EPA). 2011 PLoS ONE pmid:21853111
Waltenberger B et al. Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine. 2011 Phytomedicine pmid:20851587
Huang CB et al. Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. 2011 Arch. Oral Biol. pmid:21333271
Nahab FB et al. An open-label, single-dose, crossover study of the pharmacokinetics and metabolism of two oral formulations of 1-octanol in patients with essential tremor. 2011 Neurotherapeutics pmid:21594724
Ikemura K et al. Design of a metal primer containing a dithiooctanoate monomer and a phosphonic acid monomer for bonding of prosthetic light-curing resin composite to gold, dental precious and non-precious metal alloys. 2011 Dent Mater J pmid:21597216
Hassan N et al. Rheological properties of ovalbumin hydrogels as affected by surfactants addition. 2011 Int. J. Biol. Macromol. pmid:21262258
Minakata K et al. Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe and NADPH. 2011 J Clin Biochem Nutr pmid:22128221
Golbidi S et al. Diabetes and alpha lipoic Acid. 2011 Front Pharmacol pmid:22125537
Okada T et al. Nissen fundoplication for gastroesophageal reflux: No deterioration of gastric emptying measured by C-acetate breath test. 2011 J Indian Assoc Pediatr Surg pmid:22121311
Ma Y et al. Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment. 2011 Int J Nanomedicine pmid:22114498
Johansson H et al. A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests. 2011 BMC Genomics pmid:21824406
Garro AG et al. Reversible exposure of hydrophobic residues on albumin as a novel strategy for formulation of nanodelivery vehicles for taxanes. 2011 Int J Nanomedicine pmid:21822381
Elisia I and Kitts DD Quantification of hexanal as an index of lipid oxidation in human milk and association with antioxidant components. 2011 J Clin Biochem Nutr pmid:22128211