octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Oiso S et al. Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. 2015 J Oleo Sci pmid:26521811
Rosiak J and Olejniczak J [Polymer materials for biomedical use obtained by radiation methods. IV. The therapeutic system for local release of prostaglandins]. 1989 Polim Med pmid:2641404
Parshintsev J et al. Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols. 2015 Rapid Commun. Mass Spectrom. pmid:26395607
Fredrickson J et al. The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. 2015 J. Assist. Reprod. Genet. pmid:26342329
pmid:26280674
Wang L et al. Octanoylated ghrelin attenuates angiogenesis induced by oxLDL in human coronary artery endothelial cells via the GHSR1a-mediated NF-κB pathway. 2015 Metab. Clin. Exp. pmid:26277200
Kim SA and Rhee MS Use of caprylic acid to control pathogens (Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium) in apple juice at mild heat temperature. 2015 J. Appl. Microbiol. pmid:26257401
pmid:26253695
Kajimoto M et al. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26232235
Librán-Pérez M et al. Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid-sensing systems in rainbow trout. 2015 Domest. Anim. Endocrinol. pmid:26226227
Lemarié F et al. Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. 2015 PLoS ONE pmid:26196391
Genser B et al. Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis. 2015 Environ Health pmid:26159541
Upadhyaya I et al. Reducing Colonization and Eggborne Transmission of Salmonella Enteritidis in Layer Chickens by In-Feed Supplementation of Caprylic Acid. 2015 Foodborne Pathog. Dis. pmid:26135893
pmid:26129951
Mohanty JG and Elazhary Y Purification of IgG from serum with caprylic acid and ammonium sulphate precipitation is not superior to ammonium sulphate precipitation alone. 1989 Comp. Immunol. Microbiol. Infect. Dis. pmid:2612135
Hovorková P and Skřivanová E Use of Caprylic Acid in Broiler Chickens: Effect on Campylobacter jejuni. 2015 Foodborne Pathog. Dis. pmid:26114373
Kadota Y et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. 2015 Metab. Clin. Exp. pmid:26104959
Epprecht L et al. Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. 2015 J. Neurol. pmid:26048686
Nishitani N et al. Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. 2015 Chem Asian J pmid:26033832
Coronado MA et al. Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. 2015 Curr. Protein Pept. Sci. pmid:25961401
Arora T et al. Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission. 2015 PLoS ONE pmid:25946120
Pesce P et al. Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. 2015 J Oral Rehabil pmid:25882620
Kim SA and Rhee MS Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. 2015 Food Microbiol. pmid:25846927
Rodríguez-Moyá M and Gonzalez R Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. 2015 J Proteomics pmid:25845584
Chen Y et al. Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. 2015 Int J Pharm pmid:25841571
Damitz R and Chauhan A Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. 2015 Int J Pharm pmid:25839419
Royce LA et al. Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. 2015 Metab. Eng. pmid:25839166
Xu J et al. In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. 2015 Chem. Commun. (Camb.) pmid:25792085
Borrull A et al. New insights into the toxicity mechanism of octanoic and decanoic acids on Saccharomyces cerevisiae. 2015 Yeast pmid:25773463
Narayanan A et al. Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cancer cells in vitro. 2015 Int J Mol Sci pmid:25749477
Sengupta A et al. Production of medium chain fatty acid rich mustard oil using packed bed bioreactor. 2015 J Oleo Sci pmid:25748375
El-Ekiaby M et al. Minipool caprylic acid fractionation of plasma using disposable equipment: a practical method to enhance immunoglobulin supply in developing countries. 2015 PLoS Negl Trop Dis pmid:25719558
Alonso C et al. Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. 2015 J. Pharm. Pharmacol. pmid:25645286
Vidal H et al. Vasoactive intestinal peptide stimulates long-chain fatty acid oxidation and inhibits acetyl-coenzyme A carboxylase activity in isolated rat enterocytes. 1989 J. Biol. Chem. pmid:2564395
Obeso JI et al. The loss of function of PhaC1 is a survival mechanism that counteracts the stress caused by the overproduction of poly-3-hydroxyalkanoates in Pseudomonas putidaΔfadBA. 2015 Environ. Microbiol. pmid:25627209
Fu Y et al. Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. 2015 Appl. Microbiol. Biotechnol. pmid:25620365
Jha SK and Hayashi K A quick responding quartz crystal microbalance sensor array based on molecular imprinted polyacrylic acids coating for selective identification of aldehydes in body odor. 2015 Talanta pmid:25618646
Xu J et al. Dual receptor-targeting ⁹⁹mTc-labeled Arg-Gly-Asp-conjugated Alpha-Melanocyte stimulating hormone hybrid peptides for human melanoma imaging. 2015 Nucl. Med. Biol. pmid:25577037
Kim SA and Rhee MS Predictive model and optimization of a combined treatment of caprylic acid and citric acid for the reduction of Escherichia coli O157:H7 using the response surface methodology. 2015 Int. J. Food Microbiol. pmid:25544642
Rosenblatt J et al. Caprylic acid and glyceryl trinitrate combination for eradication of biofilm. 2015 Antimicrob. Agents Chemother. pmid:25534725
Azain MJ and Ontko JA An explanation for decreased ketogenesis in the liver of the obese Zucker rat. 1989 Am. J. Physiol. pmid:2552844
Gourcerol G et al. Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation. 2015 Aliment. Pharmacol. Ther. pmid:25523288
Vargas M et al. Human plasma-derived immunoglobulin G fractionated by an aqueous two-phase system, caprylic acid precipitation, and membrane chromatography has a high purity level and is free of detectable in vitro thrombogenic activity. 2015 Vox Sang. pmid:25469648
Socała K et al. Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice. 2015 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:25455587
Wlaź P et al. Acute anticonvulsant effects of capric acid in seizure tests in mice. 2015 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:25445478
Skřivanová E et al. Potential use of caprylic acid in broiler chickens: effect on Salmonella enteritidis. 2015 Foodborne Pathog. Dis. pmid:25407657
Goodwin D et al. Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides. 2015 Pharm. Res. pmid:25407542
Olivieri MC and Botelho LH Synergistic inhibition of hepatic ketogenesis in the presence of insulin and a cAMP antagonist. 1989 Biochem. Biophys. Res. Commun. pmid:2539126
Marchington DR et al. Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat hepatocytes. 1989 Biochem. J. pmid:2539088
Olson JE et al. Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome. 1989 J. Neurochem. pmid:2538563
Sengupta A et al. Antioxidative effect of rice bran oil and medium chain fatty acid rich rice bran oil in arsenite induced oxidative stress in rats. 2014 J Oleo Sci pmid:25354877
Nass R et al. The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. 2015 J. Clin. Endocrinol. Metab. pmid:25337923
Chang P et al. Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. 2015 J. Pharmacol. Exp. Ther. pmid:25326131
Cherniavs'kyÄ­ VV [Clinical use of 13C-breath tests in esophagogastroduodenal diseases]. 2014 Mar-Apr Lik. Sprava pmid:25286602
Caballero E et al. Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases. 2014 PLoS ONE pmid:25248107
Schubert MM et al. Coffee for morning hunger pangs. An examination of coffee and caffeine on appetite, gastric emptying, and energy intake. 2014 Appetite pmid:25218717
Coenen MJ et al. Nanostructuring of self-assembled porphyrin networks at a solid/liquid interface: local manipulation under global control. 2014 Chemphyschem pmid:25146424
Razmakhnin EV et al. [The atomic emission analysis under examination of composition of gallstones]. 2014 Klin. Lab. Diagn. pmid:25080794
el Alaoui-Talibi Z and Moravec J Limitation of long chain fatty acid oxidation in volume over-loaded rat hearts. 1989 Adv. Exp. Med. Biol. pmid:2506741
Wolfram G et al. [Distribution and elimination of medium- and long-chain fatty acids of a fat emulsion in lipoproteins of severely injured patients following bolus injection]. 1989 Z Ernahrungswiss pmid:2503947
Zieve L and Lyftogt C Valproic acid induction of coma in rats: synergism with NH4+ and pentobarbital. 1989 Metab Brain Dis pmid:2502706
Jensen GL et al. Dietary modification of chyle composition in chylothorax. 1989 Gastroenterology pmid:2502466
Zhu J et al. The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates. 2014 Nutrients pmid:25010553
el Alaoui-Talibi Z and Moravec J Carnitine transport and exogenous palmitate oxidation in chronically volume-overloaded rat hearts. 1989 Biochim. Biophys. Acta pmid:2499353
Bagai S et al. Lipid-modified polyethylenimine-mediated DNA attraction evaluated by molecular dynamics simulations. 2014 J Phys Chem B pmid:24918771
Gasco MR et al. Microemulsions as topical delivery vehicles: ocular administration of timolol. 1989 J Pharm Biomed Anal pmid:2490750
Salentinig S et al. pH-responsive micelles based on caprylic acid. 2014 Langmuir pmid:24905895
Matsumoto Y et al. Rectal absorption enhancement of gentamicin in rabbits from hollow type suppositories by sodium salicylate or sodium caprylate. 1989 Drug Des. Deliv. pmid:2490276
Mitkov D Octanoate action on muscular protein catabolism in rats. 1989 Folia Med (Plovdiv) pmid:2490157
Dalgaard L et al. Resolution and binding site determination of D,L-thyronine by high-performance liquid chromatography using immobilized albumin as chiral stationary phase. Determination of the optical purity of thyroxine in tablets. 1989 J Pharm Biomed Anal pmid:2488636
Morimoto K et al. Effect of medium-chain fatty acid salts on penetration of a hydrophilic compound and a macromolecular compound across rabbit corneas. 1989 Nov-Dec Arch Int Pharmacodyn Ther pmid:2484010
Sun X et al. Tuning the self-assembly of oligothiophenes on chemical vapor deposition graphene: effect of functional group, solvent, and substrate. 2014 Chem Asian J pmid:24839081
Lavieri NA et al. Investigating the control of Listeria monocytogenes on a ready-to-eat ham product using natural antimicrobial ingredients and postlethality interventions. 2014 Foodborne Pathog. Dis. pmid:24824223
De Preter V et al. Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. 2015 Gut pmid:24811995
Lavieri NA et al. Investigating the control of Listeria monocytogenes on alternatively-cured frankfurters using natural antimicrobial ingredients or post-lethality interventions. 2014 Meat Sci. pmid:24769878
Darling RA et al. Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760994
Adamczak M Characteristic of fungal lipases and their application in synthesis of structered lipids. 2003 Commun. Agric. Appl. Biol. Sci. pmid:24757817
Layek B and Singh J N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. 2012 Carbohydr Polym pmid:24750737
Tao Y et al. Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. 2014 Enzyme Microb. Technol. pmid:24731826
Marquez A et al. Optimization and validation of an automated DHS-TD-GC-MS method for the determination of aromatic esters in sweet wines. 2014 Talanta pmid:24725861
Morais V et al. Immunoglobulin purification by caprylic acid. 2014 Methods Mol. Biol. pmid:24648074
Librán-Pérez M et al. Central administration of oleate or octanoate activates hypothalamic fatty acid sensing and inhibits food intake in rainbow trout. 2014 Physiol. Behav. pmid:24631300
Chen YJ et al. Production and characterization of medium-chain-length polyhydroxyalkanoates by Pseudomonas mosselii TO7. 2014 J. Biosci. Bioeng. pmid:24630613
Ke L et al. Systemic and renal haemodynamic effects of fluid bolus therapy: sodium chloride versus sodium octanoate-balanced solution. 2014 Crit Care Resusc pmid:24588433
Kajimoto M et al. Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. 2014 Am. J. Physiol. Heart Circ. Physiol. pmid:24531815
Paulsen SJ et al. Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. 2014 PLoS ONE pmid:24520357
Bruno G et al. 13C-octanoic acid breath test to study gastric emptying time. 2013 Eur Rev Med Pharmacol Sci pmid:24443070
Gadotti C et al. Inhibitory effect of combinations of caprylic acid and nisin on Listeria monocytogenes in queso fresco. 2014 Food Microbiol. pmid:24387845
Qin XL et al. Fatty acid specificity of T1 lipase and its potential in acylglycerol synthesis. 2014 J. Sci. Food Agric. pmid:24338705
Kössler F and Nasledov GA Effects of Na-octanoate on potassium contractures in normal and denervated frog tonic fibres. 1986 Gen. Physiol. Biophys. pmid:2433184
Shilling M et al. Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile. 2013 J Med Food pmid:24328700
Antón MJ et al. Aromatic profile of ciders by chemical quantitative, gas chromatography-olfactometry, and sensory analysis. 2014 J. Food Sci. pmid:24313985
Bokhout BA et al. Porcine IgG. Isolation of two IgG-subclasses and anti-IgG class- and subclass-specific antibodies. 1986 Mol. Immunol. pmid:2427943
Lee YC and Johnson JH Determination of sodium caprylate in plasma volume expanders by gas chromatography. 1986 J. Chromatogr. pmid:2426293
Al-Abdulla I et al. Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. 2014 J. Immunol. Methods pmid:24246428
Zhang JF et al. A new derivatization method to enhance sensitivity for the determination of low levels of valproic acid in human plasma. J Chromatogr Sci pmid:24243686
de Oliveira AL et al. Adrenergic metabolic and hemodynamic effects of octopamine in the liver. 2013 Int J Mol Sci pmid:24196353
Scott G et al. Pickering stabilized peptide gel particles as tunable microenvironments for biocatalysis. 2013 Langmuir pmid:24144273
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902
Horner KM et al. Reproducibility of gastric emptying in overweight and obese males. 2014 Clin Nutr pmid:24074547