octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypothyroidism D007037 32 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Hemorrhage D006470 15 associated lipids
Malocclusion D008310 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Solis de Los Santos F et al. Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens. 2008 Poult. Sci. pmid:18340004
Bhanushali JK et al. Simple method to purify chicken immunoglobulin G. 1994 Poult. Sci. pmid:7937478
Hughes RJ et al. A method for collecting breath samples from individual chickens for analysis of 13CO(2), H(2), and CH(4). 2008 Poult. Sci. pmid:18753448
Metcalf JH et al. Water administration of the medium-chain fatty acid caprylic acid produced variable efficacy against enteric Campylobacter colonization in broilers. 2011 Poult. Sci. pmid:21248350
Kollanoor-Johny A et al. Caprylic acid reduces Salmonella Enteritidis populations in various segments of digestive tract and internal organs of 3- and 6-week-old broiler chickens, therapeutically. 2012 Poult. Sci. pmid:22700516
Solis de los Santos F et al. The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. 2009 Poult. Sci. pmid:19096058
Tien ES et al. Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha). 2006 PPAR Res pmid:17259669
Allison F et al. The oxidation of octanoic acid by cultured amniotic fluid cells: the effect of cell type and passage number. 1988 Prenat. Diagn. pmid:3405975
Bennett MJ et al. Prenatal diagnosis of medium-chain acyl-coenzyme A dehydrogenase deficiency. 1987 Prenat. Diagn. pmid:3575262
Habeeb AF and Francis RD Preparation of human immunoglobulin by caprylic acid precipitation. 1984 Prep. Biochem. pmid:6718324
Omura T Recollection of the early years of the research on cytochrome P450. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:22156409
Pösö AR and Mortimore GE Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6589593
Jenkins DL and Griffith OW Antiketogenic and hypoglycemic effects of aminocarnitine and acylaminocarnitines. 1986 Proc. Natl. Acad. Sci. U.S.A. pmid:3455765
Gutierrez JA et al. Ghrelin octanoylation mediated by an orphan lipid transferase. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18443287
Merritt ME et al. Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18056642
Pi-Sunyer FX Effect of long- and medium-chain fatty acids on insulin secretion from pieces of rat pancreas. 1975 Proc. Soc. Exp. Biol. Med. pmid:1144459
Paquet RJ et al. Effects of thiamine deficiency and octanoate administration, in vivo, on gluconeogenesis in rat kidney slices and on amino acid profile in rat liver. 1972 Proc. Soc. Exp. Biol. Med. pmid:5039394
Morrow RJ et al. Functional utilization of palmitate, octanoate, and glucose by the isolated rat heart. 1973 Proc. Soc. Exp. Biol. Med. pmid:4683244
Maragoudakis ME et al. Metabolism of octanoate and its effect on glucose and palmitate utilization by isolated fat cells. 1975 Proc. Soc. Exp. Biol. Med. pmid:236573
McDonough KH and Spitzer JJ Effects of hypoxia and reoxygenation on adult rat heart cell metabolism. 1983 Proc. Soc. Exp. Biol. Med. pmid:6412237