octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Chest Pain D002637 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Dyspepsia D004415 5 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
McDaniel HG Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. 1975 Am. J. Physiol. pmid:1211489
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Chacín J et al. Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. 1986 Am. J. Physiol. pmid:3090895
Coyle EF et al. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. 1997 Am. J. Physiol. pmid:9277379
Ben Cheikh R et al. Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates. 1994 Am. J. Physiol. pmid:8203607
Hütter JF et al. Effect of fatty acid oxidation on efficiency of energy production in rat heart. 1985 Am. J. Physiol. pmid:4051011
Azain MJ and Ontko JA An explanation for decreased ketogenesis in the liver of the obese Zucker rat. 1989 Am. J. Physiol. pmid:2552844
Witters LA and Trasko CS Regulation of hepatic free fatty acid metabolism by glucagon and insulin. 1979 Am. J. Physiol. pmid:157075
Chacín J et al. Role of fatty acid oxidation in mechanism of action of gastric secretagogues. 1980 Am. J. Physiol. pmid:6768310
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
REICH WJ et al. The treatment of monilial vaginitis with caprylic acid. 1953 Am. J. Obstet. Gynecol. pmid:13016687
Talley NJ et al. Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? 2001 Am. J. Gastroenterol. pmid:11374677
Vanheel H et al. Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. 2017 Am. J. Gastroenterol. pmid:27958284
Lee JS et al. Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test. 2000 Am. J. Gastroenterol. pmid:11051344
Cappello G et al. Gastric emptying of a solid-liquid meal measured with 13C octanoic acid breath test and real-time ultrasonography: a comparative study. 2000 Am. J. Gastroenterol. pmid:11095323
Rabinowitz JL et al. The effects of intravenous sodium octanoate on the rhesus monkey. 1978 Am. J. Gastroenterol. pmid:96693
Choi MG et al. Reproducibility and simplification of 13C-octanoic acid breath test for gastric emptying of solids. 1998 Am. J. Gastroenterol. pmid:9448183
Miele L et al. Hepatic mitochondrial beta-oxidation in patients with nonalcoholic steatohepatitis assessed by 13C-octanoate breath test. 2003 Am. J. Gastroenterol. pmid:14572600
Perri F et al. Patterns of symptoms in functional dyspepsia: role of Helicobacter pylori infection and delayed gastric emptying. 1998 Am. J. Gastroenterol. pmid:9820377