octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Dyspepsia D004415 5 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Stomach Diseases D013272 7 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Chronic Disease D002908 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Saito K et al. An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. 2017 Toxicol In Vitro pmid:27965148
Köllner S et al. Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. 2017 Eur J Pharm Biopharm pmid:28323109
Andrade López JM et al. Genetic basis of octanoic acid resistance in Drosophila sechellia: functional analysis of a fine-mapped region. 2017 Mol. Ecol. pmid:28035709
Kandula M et al. Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. 2016 Int. Immunopharmacol. pmid:27716592
Kateja N et al. Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). 2016 Biotechnol J pmid:27447837
Lemarié F et al. Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. 2016 Biochim. Biophys. Acta pmid:27317984
Sawatani Y et al. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. 2016 Bioorg. Med. Chem. pmid:27301681
Kubota K et al. The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. 2016 Eur J Pharm Sci pmid:26965004
Nakajima K et al. Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. 2016 Biomed. Res. pmid:28003581
Hogan S et al. Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. 2016 Antimicrob. Agents Chemother. pmid:27458213
Lockman KA et al. Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. 2016 Lipids Health Dis pmid:27368608
Voller B et al. Dose-escalation study of octanoic acid in patients with essential tremor. 2016 J. Clin. Invest. pmid:26927672
Diaz De Rienzo MA et al. Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. 2016 Appl. Microbiol. Biotechnol. pmid:26825819
Librán-Pérez M et al. Effects of insulin treatment on the response to oleate and octanoate of food intake and fatty acid-sensing systems in rainbow trout. 2015 Domest. Anim. Endocrinol. pmid:26226227
Upadhyaya I et al. Reducing Colonization and Eggborne Transmission of Salmonella Enteritidis in Layer Chickens by In-Feed Supplementation of Caprylic Acid. 2015 Foodborne Pathog. Dis. pmid:26135893
Hovorková P and Skřivanová E Use of Caprylic Acid in Broiler Chickens: Effect on Campylobacter jejuni. 2015 Foodborne Pathog. Dis. pmid:26114373
Kadota Y et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. 2015 Metab. Clin. Exp. pmid:26104959
Epprecht L et al. Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal. 2015 J. Neurol. pmid:26048686
Nishitani N et al. Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. 2015 Chem Asian J pmid:26033832
Coronado MA et al. Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. 2015 Curr. Protein Pept. Sci. pmid:25961401