octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Memory Disorders D008569 33 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Endotoxemia D019446 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Poultry Diseases D011201 21 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Midelfort KS et al. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. 2013 Protein Eng. Des. Sel. pmid:23012440
Librán-Pérez M et al. Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23010243
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902
Zimmermann S et al. Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. 2012 Jan-Mar Sci Pharm pmid:22396915
Morais V and Massaldi H A model mechanism for protein precipitation by caprylic acid: application to plasma purification. 2012 Jan-Feb Biotechnol. Appl. Biochem. pmid:22332745
Kaiya H et al. Determination of nonmammalian ghrelin. 2012 Meth. Enzymol. pmid:22975047
Kojima M et al. Purification of rat and human ghrelins. 2012 Meth. Enzymol. pmid:22975045
Kashiwagi S et al. Safety of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate in post-marketing surveillance. 2012 Int. J. Antimicrob. Agents pmid:22871369
Calandra P et al. Self-assembly in surfactant-based liquid mixtures: octanoic acid/Bis(2-ethylhexyl)amine systems. 2012 J Colloid Interface Sci pmid:22041199
Smits NG et al. Development of a flow cytometric immunoassay for recombinant bovine somatotropin-induced antibodies in serum of dairy cows. 2012 Drug Test Anal pmid:21964757
Hossain MA et al. Effect of vehicle systems, pH and enhancers on the permeation of highly lipophilic aripiprazole from Carbopol 971P gel systems across human cadaver skin. 2012 Drug Dev Ind Pharm pmid:22067044
Isidorov VA et al. Gas chromatographic-mass spectrometric investigation of volatile and extractable compounds of crude royal jelly. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22245368
Kobayashi T et al. Synthesis of 6-O-Octanoyl-1,2-O-isopropylidene-α-D-glucofuranose by lipase-catalyzed esterification in an organic solvent. 2012 J Oleo Sci pmid:22277891
Kuo CH et al. High yield of wax ester synthesized from cetyl alcohol and octanoic acid by lipozyme RMIM and Novozym 435. 2012 Int J Mol Sci pmid:23109878
Gumel AM et al. Biosynthesis and characterization of polyhydroxyalkanoates copolymers produced by Pseudomonas putida Bet001 isolated from palm oil mill effluent. 2012 PLoS ONE pmid:23028854
Tokudome Y and Otsuka M Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. 2012 Biol. Pharm. Bull. pmid:22975500
Eursakun S et al. Studies on the fractionation of equine antivenom IgG by combinations of ammonium sulfate and caprylic acid. 2012 Toxicon pmid:22842065
De Silva A and Bloom SR Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity. 2012 Gut Liver pmid:22375166
Kim H et al. Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. 2012 Ann Dermatol pmid:22363147
Focsan AL et al. EPR study of the astaxanthin n-octanoic acid monoester and diester radicals on silica-alumina. 2012 J Phys Chem B pmid:23039790