octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

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What functions are associated with octanoic acid?


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What lipids are associated with octanoic acid?

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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Vinay P et al. Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. 1976 Am. J. Physiol. pmid:970471
Burns AH and Reddy WJ Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. 1978 Am. J. Physiol. pmid:727249
Azain MJ and Ontko JA An explanation for decreased ketogenesis in the liver of the obese Zucker rat. 1989 Am. J. Physiol. pmid:2552844
Witters LA and Trasko CS Regulation of hepatic free fatty acid metabolism by glucagon and insulin. 1979 Am. J. Physiol. pmid:157075
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427
Kim JY et al. Lipid oxidation is reduced in obese human skeletal muscle. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052958
Benthem L et al. Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11093916
Bezaire V et al. Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: essential role in fatty acid oxidation. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16219667
Cha BS et al. Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15727952
Sakata I et al. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19401456