| MeSH term | MeSH ID | Detail |
|---|---|---|
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Hemorrhage | D006470 | 15 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zwiebel FM et al. | Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. | 1982 | Biochemistry | pmid:7074018 |
| Lo YC et al. | Substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement. | 2005 | Biochemistry | pmid:15697222 |
| Salesse R et al. | Modulation of adenylate cyclase activity by the physical state of pigeon erythrocyte membrane. 1. Parallel drug-induced changes in the bilayer fluidity and adenylate cyclase activity. | 1982 | Biochemistry | pmid:6282308 |
| Pohl J et al. | Long-chain fatty acid uptake into adipocytes depends on lipid raft function. | 2004 | Biochemistry | pmid:15065861 |
| Li W et al. | Reconstitution of the M13 major coat protein and its transmembrane peptide segment on a DNA template. | 2007 | Biochemistry | pmid:17595059 |
| Jiang Y et al. | The soluble acyl-acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family. | 2006 | Biochemistry | pmid:16906759 |
| Hsieh CH et al. | The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. | 2017 | Biochemistry | pmid:28603981 |
| Carrington MJ et al. | Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. | 1981 | Biochem. Soc. Trans. | pmid:7215663 |
| Littlechild JA et al. | Hyperthermophilic dehydrogenase enzymes. | 2004 | Biochem. Soc. Trans. | pmid:15046583 |
| Priestman DA et al. | Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes. | 1997 | Biochem. Soc. Trans. | pmid:9056999 |
| Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
| Gandhi NN and Mukherjee KD | Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases. | 2000 | Biochem. Soc. Trans. | pmid:11171278 |
| Bhuiyan AK and Pande SV | One-step facile synthesis of radioactive acyl-CoA and acylcarnitines using rat liver outer mitochondrial membrane as the enzyme source. | 1991 | Biochem. Soc. Trans. | pmid:1889559 |
| Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
| GarcÃa-Villafranca J and Castro J | Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. | 2002 | Biochem. Pharmacol. | pmid:12093476 |
| Fulgencio JP et al. | Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes. | 2001 | Biochem. Pharmacol. | pmid:11448453 |
| Veitch K and Van Hoof F | In vitro effects of eight-carbon fatty acids on oxidations in rat liver mitochondria. | 1990 | Biochem. Pharmacol. | pmid:2242043 |
| Sarnatskaya VV et al. | Effect of protein-bound uraemic toxins on the thermodynamic characteristics of human albumin. | 2002 | Biochem. Pharmacol. | pmid:11960605 |
| Swartzentruber MS and Harris RA | Inhibition of metabolic processes by coenzyme-A-sequestering aromatic acids. Prevention by para-chloro- and para-nitrobenzoic acids. | 1987 | Biochem. Pharmacol. | pmid:3117062 |
| Schudt C and Simon A | Effects of sodium 2-[5-(4-chlorophenyl)pentyl]-oxirane-2-carboxylate (POCA) on carbohydrate and fatty acid metabolism in liver and muscle. | 1984 | Biochem. Pharmacol. | pmid:6437406 |
| el-Aleem SA and Schulz H | Evaluation of inhibitors of fatty acid oxidation in rat myocytes. | 1987 | Biochem. Pharmacol. | pmid:3689454 |
| Deaciuc IV et al. | Studies on the mechanism of action of the hypoglycemic agent, 2-(3-methylcinnamylhydrazono)-propionate (BM 42.304). | 1983 | Biochem. Pharmacol. | pmid:6651864 |
| Olubadewo JO et al. | Effects of 8-N,N-diethylamino-octyl-3,4,5-trimethoxybenzoate (TMB-8) HCl and verapamil on the metabolism of free fatty acid by hepatocytes. | 1988 | Biochem. Pharmacol. | pmid:3358779 |
| Massolini G et al. | Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. | 1993 | Biochem. Pharmacol. | pmid:8216380 |
| Grolier P and Elcombe CR | In vitro inhibition of carnitine acyltransferase activity in mitochondria from rat and mouse liver by a diethylhexylphthalate metabolite. | 1993 | Biochem. Pharmacol. | pmid:8452557 |
| Haas R et al. | Salicylate-induced loose coupling: protonmotive force measurements. | 1985 | Biochem. Pharmacol. | pmid:3977963 |
| Krahenbuhl S and Brass EP | Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:2009071 |
| Rozas I et al. | Effects of acute valproate administration on carnitine metabolism in mouse serum and tissues. | 1990 | Biochem. Pharmacol. | pmid:2105093 |
| Thayer WS | Inhibition of mitochondrial fatty acid oxidation in pentenoic acid-induced fatty liver. A possible model for Reye's syndrome. | 1984 | Biochem. Pharmacol. | pmid:6712730 |
| Porter DJ | Binding of 2-acetylpyridine-5-[(2-chloroanilino)thiocarbonyl] thiocarbonohydrazone (BW348U87) to human serum albumin. | 1992 | Biochem. Pharmacol. | pmid:1417962 |
| Ohtsuka Y and Griffith OW | L-carnitine protection in ammonia intoxication. Effect of aminocarnitine on carnitine-dependent metabolism and acute ammonia toxicity. | 1991 | Biochem. Pharmacol. | pmid:2039546 |
| Schepkin V et al. | NMR study of lipoic acid binding to bovine serum albumin. | 1994 | Biochem. Mol. Biol. Int. | pmid:7987256 |
| Kalbag SS and Palekar AG | Sodium benzoate inhibits fatty acid oxidation in rat liver: effect on ammonia levels. | 1988 | Biochem. Med. Metab. Biol. | pmid:3190922 |
| Shipp DA et al. | Development of fatty acid oxidation in neonatal guinea-pig liver. | 1982 | Biochem. J. | pmid:7165728 |
| Ferré P et al. | Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. | 1981 | Biochem. J. | pmid:7340842 |
| Zammit VA | The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. | 1980 | Biochem. J. | pmid:7470052 |
| Petcu LG and Plaut GW | NADP-specific isocitrate dehydrogenase in regulation of urea synthesis in rat hepatocytes. | 1980 | Biochem. J. | pmid:7470071 |
| Kasumov T et al. | Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. | 2005 | Biochem. J. | pmid:15773815 |
| Buse MG et al. | Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats. | 1975 | Biochem. J. | pmid:1200982 |
| Guo W et al. | Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate. | 2000 | Biochem. J. | pmid:10880345 |
| Ferré P et al. | Development and regulation of ketogenesis in hepatocytes isolated from newborn rats. | 1983 | Biochem. J. | pmid:6626164 |
| Bauché F et al. | Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria. | 1983 | Biochem. J. | pmid:6661181 |
| Foxworthy PS and Eacho PI | Inhibition of hepatic fatty acid oxidation at carnitine palmitoyltransferase I by the peroxisome proliferator 2-hydroxy-3-propyl-4-[6-(tetrazol-5-yl) hexyloxy]acetophenone. | 1988 | Biochem. J. | pmid:3415664 |
| Leclercq P et al. | Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats. | 1997 | Biochem. J. | pmid:9230136 |
| Halestrap AP | The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+. | 1987 | Biochem. J. | pmid:3663110 |
| Oshino N et al. | The properties of hydrogen peroxide production under hyperoxic and hypoxic conditions of perfused rat liver. | 1975 | Biochem. J. | pmid:167718 |
| Iwahashi H et al. | Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide. | 2002 | Biochem. J. | pmid:11742529 |
| Berger M et al. | Glucose metabolism in perfused skeletal muscle. Effects of starvation, diabetes, fatty acids, acetoacetate, insulin and exercise on glucose uptake and disposition. | 1976 | Biochem. J. | pmid:136249 |
| Reed WD et al. | The effects of insulin and glucagon on ketone-body turnover. | 1984 | Biochem. J. | pmid:6383348 |
| Kragh-Hansen U | Octanoate binding to the indole- and benzodiazepine-binding region of human serum albumin. | 1991 | Biochem. J. | pmid:1996962 |