octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hepatic Encephalopathy D006501 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Liver Failure D017093 5 associated lipids
Asthenia D001247 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Dyspepsia D004415 5 associated lipids
Chest Pain D002637 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Schistosomiasis D012552 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Malocclusion D008310 3 associated lipids
Giardiasis D005873 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Vinay P et al. Effect of fatty acids on renal ammoniagenesis in in vivo and in vitro studies. 1976 Am. J. Physiol. pmid:970471
Barbee RW et al. T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. 1988 Am. J. Physiol. pmid:2830793
Burns AH and Reddy WJ Amino acid stimulation of oxygen and substrate utilization by cardiac myocytes. 1978 Am. J. Physiol. pmid:727249
REES ED and KLINE DL Metabolism of octanoate by fatty liver slices. 1957 Am. J. Physiol. pmid:13470069
Beaufrere B et al. Apparent decreased oxidation and turnover of leucine during infusion of medium-chain triglycerides. 1985 Am. J. Physiol. pmid:3895976
Barron JT et al. Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. 1996 Am. J. Physiol. pmid:8764234
Bonen A et al. Palmitate transport and fatty acid transporters in red and white muscles. 1998 Am. J. Physiol. pmid:9725814
Azain MJ and Ontko JA An explanation for decreased ketogenesis in the liver of the obese Zucker rat. 1989 Am. J. Physiol. pmid:2552844
Witters LA and Trasko CS Regulation of hepatic free fatty acid metabolism by glucagon and insulin. 1979 Am. J. Physiol. pmid:157075
Bielefeld DR et al. Altered sensitivity of chronic diabetic rat heart to calcium. 1983 Am. J. Physiol. pmid:6362427