octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Malocclusion D008310 3 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Obesity D009765 29 associated lipids
Parkinson Disease D010300 53 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Reye Syndrome D012202 14 associated lipids
Schistosomiasis D012552 4 associated lipids
Seizures D012640 87 associated lipids
Snake Bites D012909 1 associated lipids
Starvation D013217 47 associated lipids
Stomach Diseases D013272 7 associated lipids
Urinary Incontinence D014549 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Rosario P and Medina JM Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. 1980 Rev. Esp. Fisiol. pmid:7221165
Morgenthaler JJ et al. Fatty acid patterns during plasma fractionation. 1980 Vox Sang. pmid:7415075
Schenk J et al. Treatment of choledocholithiasis using the transpapillary perfusion technique. 1980 Endoscopy pmid:7428727
Krisans SK et al. Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments. 1980 J. Biol. Chem. pmid:7430088
Waymack PP et al. Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart. 1980 J. Biol. Chem. pmid:7430101
Schenk J et al. [Irrigation treatment of concrements in the common bile duct with octanoate (Capmul 8210) (author's transl)]. 1980 Dtsch. Med. Wochenschr. pmid:7408673
May ME et al. Mechanism of the stimulation of branched chain oxoacid oxidation in liver by carnitine. 1980 J. Biol. Chem. pmid:7410370
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Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777
Caffier G and Küchler G [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. 1980 Acta Biol. Med. Ger. pmid:6969509
Sánchez-Serrano D et al. Enhancement of ouabain arrhythmias by fatty acids. 1980 J. Cardiovasc. Pharmacol. pmid:6156330
Chan SC Monitoring serum valproic acid by gas chromatography with electron-capture detection. 1980 Clin. Chem. pmid:6774836
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470
Chace KV and Odessey R The utilization by rabbit aorta of carbohydrates, fatty acids, ketone bodies, and amino acids as substrates for energy production. 1981 Circ. Res. pmid:7226445
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Rosario P and Medina JM Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. 1981 Rev. Esp. Fisiol. pmid:7244329
Henze K et al. The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6118180
Pegg DE et al. Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. 1981 Transplantation pmid:7330963