octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

Cross Reference

Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Insulin Resistance D007333 99 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Malocclusion D008310 3 associated lipids
Memory Disorders D008569 33 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Obesity D009765 29 associated lipids
Parkinson Disease D010300 53 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Reye Syndrome D012202 14 associated lipids
Schistosomiasis D012552 4 associated lipids
Seizures D012640 87 associated lipids
Snake Bites D012909 1 associated lipids
Starvation D013217 47 associated lipids
Stomach Diseases D013272 7 associated lipids
Urinary Incontinence D014549 4 associated lipids
Per page 10 20 50 100 | Total 73

PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2110
Authors Title Published Journal PubMed Link
Vauhkonen M and Somerharju P Parinaroyl and pyrenyl phospholipids as probes for the lipid surface layer of human low density lipoproteins. 1989 Biochim. Biophys. Acta pmid:2765542
Einarsson R The binding of 1-anilino-8-naphthalenesulfonate, heparin, salicylate and caprylate by human antithrombin III. 1976 Biochim. Biophys. Acta pmid:974107
Tachibana S et al. Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes. 2005 Biochim. Biophys. Acta pmid:16226916
Dorset DL Co-solubility of saturated cholesteryl esters: a comparison of calculated and experimental binary phase diagrams. 1988 Biochim. Biophys. Acta pmid:3179332
Martínez Izquierdo JA et al. Fatty acid-glucose interaction in the control of protein synthesis by isolated rat lung cells. 1983 Biochim. Biophys. Acta pmid:6615881
Merrill AR et al. Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. 1986 Biochim. Biophys. Acta pmid:3081028
Veerkamp JH et al. An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. 1986 Biochim. Biophys. Acta pmid:3081042
GLENN JL et al. Rare-earth fatty liver. I. Octanoate oxidation and energy production. 1962 Biochim. Biophys. Acta pmid:13899206
DIANZANI MU and MARINARI U The octanoate oxidation by mitochondria from faty livers. 1961 Biochim. Biophys. Acta pmid:13722612
McDonough KH et al. Effects of oxygen radicals on substrate oxidation by cardiac myocytes. 1987 Biochim. Biophys. Acta pmid:2822138
Groot PH and Hülsmann WC The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria. 1973 Biochim. Biophys. Acta pmid:4741907
Barron JT et al. Oxidation of acetate and octanoate and its relation to glucose metabolism in contracting porcine carotid artery. 1997 Biochim. Biophys. Acta pmid:9452767
Cheng Y and Hauton D Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase. 2008 Biochim. Biophys. Acta pmid:18722549
González-Manchón C et al. Control of gluconeogenesis: role of fatty acids in the alpha-adrenergic response. 1988 Biochim. Biophys. Acta pmid:3191164
Jakobs BS et al. Beta-oxidation of fatty acids in cultured human skin fibroblasts devoid of the capacity for oxidative phosphorylation. 1994 Biochim. Biophys. Acta pmid:8123680
Decagny B et al. 1H-NMR on line monitoring of water activity during lipase catalysed esterification. 1998 Biochim. Biophys. Acta pmid:9748540
Yon JO et al. Incorporation of extracellular phospholipids and their effect on the growth and lipid metabolism of the Saccharomyces cerevisiae cho1/pss mutant. 1998 Biochim. Biophys. Acta pmid:9767089
Noy N and Zakim D Substrate specificity of fatty-acyl-CoA ligase in liver microsomes. 1985 Biochim. Biophys. Acta pmid:3970953
Brandes R et al. The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. 1985 Biochim. Biophys. Acta pmid:4027259
Apel CL et al. Self-assembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for the encapsulation of biopolymers. 2002 Biochim. Biophys. Acta pmid:11825583
González-Manchón C et al. Ca2(+)-fatty acid interaction in the control of hepatic gluconeogenesis. 1990 Biochim. Biophys. Acta pmid:2310772
Zabłocki K et al. The inhibitory effect of octanoate, palmitate and oleate on glucose formation in rabbit kidney tubules. 1983 Biochim. Biophys. Acta pmid:6838901
Evtodienko VY et al. Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. 1996 Biochim. Biophys. Acta pmid:8664324
Salesse R and Garnier J Effects of drugs on pigeon erythrocyte membrane and asymmetric control or adenylate cyclase by the lipid bilayer. 1979 Biochim. Biophys. Acta pmid:222319
Magliano P et al. Repercussion of a deficiency in mitochondrial ß-oxidation on the carbon flux of short-chain fatty acids to the peroxisomal ß-oxidation cycle in Aspergillus nidulans. 2010 Biochim. Biophys. Acta pmid:20736083
Shimshoni JA et al. Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. 2011 Biochim. Biophys. Acta pmid:21184843
Nomura T et al. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. 1983 Biochim. Biophys. Acta pmid:6317044
Bohnensack R and Fritz S Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model. 1991 Biochim. Biophys. Acta pmid:2009283
Salesse R et al. [Intensity and anisotropy decays measurement of perylene in pigeon erythrocyte membrane. Comparison with an isotropic viscous medium (author's transl)]. 1981 Nov-Dec Biochimie pmid:7332761
Pérez-Diaz J et al. Preparation and metabolic characterization of isolated rat lung cells. 1977 Biochimie pmid:195638
Pochapsky SS et al. Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. 1990 Jul-Aug Bioconjug. Chem. pmid:2096916
van Ginkel CG et al. Substrate specificity of a long-chain alkylamine-degrading Pseudomonas sp isolated from activated sludge. 2008 Biodegradation pmid:17492358
Goussen C et al. Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. 2017 BioDrugs pmid:28508264
Nagata J et al. Effects of structured lipids containing eicosapentaenoic or docosahexaenoic acid and caprylic acid on serum and liver lipid profiles in rats. 2004 Biofactors pmid:15630273
Kundu S and Roy D Structural study of biologically significant ligands with major birch pollen allergen Betv1 by docking and molecular dynamics simulation. 2010 Bioinformation pmid:20978606
Kumar S Comparative modeling and molecular docking of orphan human CYP4V2 protein with fatty acid substrates: Insights into substrate specificity. 2011 Bioinformation pmid:22355237
Pahl-Wostl C and Seelig J Ketogenesis in the living rat followed by 13C-NMR spectroscopy. Infusion of [1,3-13C]octanoate. 1987 Biol. Chem. Hoppe-Seyler pmid:3593540
Lemmen C et al. Utilization of medium-chain triglycerides and octanoic acid by cultured human fibroblasts and lymphoblasts. 1988 Biol. Chem. Hoppe-Seyler pmid:3242549
Küster J et al. Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. 1989 Biol. Chem. Hoppe-Seyler pmid:2692615
Kuge Y et al. [1-11C]Octanoate as a PET tracer for studying ischemic stroke: evaluation in a canine model of thromboembolic stroke with positron emission tomography. 2000 Biol. Pharm. Bull. pmid:10963308
Tokudome Y and Otsuka M Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. 2012 Biol. Pharm. Bull. pmid:22975500
Uchida M and Shimizu K 13C-acetic acid is more sensitive than 13C-octanoic acid for evaluating gastric emptying of liquid enteral nutrient formula by breath test in conscious rats. 2007 Biol. Pharm. Bull. pmid:17329843
Solano S et al. Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. 2012 Biologicals pmid:22266304
Johnston A et al. Low pH, caprylate incubation as a second viral inactivation step in the manufacture of albumin. Parametric and validation studies. 2003 Biologicals pmid:12935811
Stucki M et al. Investigations of prion and virus safety of a new liquid IVIG product. 2008 Biologicals pmid:18337119
Mpandi M et al. Partitioning and inactivation of viruses by the caprylic acid precipitation followed by a terminal pasteurization in the manufacturing process of horse immunoglobulins. 2007 Biologicals pmid:17470396
Burnouf T et al. Assessment of viral inactivation during pH 3.3 pepsin digestion and caprylic acid treatment of antivenoms. 2007 Biologicals pmid:17363271
Simsiriwong P et al. A study on the use of caprylic acid and ammonium sulfate in combination for the fractionation of equine antivenom F(ab')(2). 2012 Biologicals pmid:22704919
Burnouf T et al. Assessment of the viral safety of antivenoms fractionated from equine plasma. 2004 Biologicals pmid:15536042
Dichtelmüller H et al. Inactivation of lipid enveloped viruses by octanoic Acid treatment of immunoglobulin solution. 2002 Biologicals pmid:12127315