octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Liver Failure D017093 5 associated lipids
Chickenpox D002644 1 associated lipids
Chylothorax D002916 1 associated lipids
Gastroparesis D018589 2 associated lipids
Gallstones D042882 3 associated lipids
Dyspepsia D004415 5 associated lipids
Snake Bites D012909 1 associated lipids
Prion Diseases D017096 2 associated lipids
Asthenia D001247 5 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Maragoudakis ME et al. Metabolism of octanoate and its effect on glucose and palmitate utilization by isolated fat cells. 1975 Proc. Soc. Exp. Biol. Med. pmid:236573
Lamabadusuriya SP et al. Influence of mixtures of taurocholate, fatty acids, and monolein on the toxic effects of deoxycholate in rat jejunum in vivo. 1975 Gastroenterology pmid:125213
Berne C The effect of fatty acids and ketone bodies on the biosynthesis of insulin in isolated pancreatic islets of obese hyperglycemic mice. 1975 Horm. Metab. Res. pmid:1102408
Jomain-Baum M and Hanson RW Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia. 1975 J. Biol. Chem. pmid:1194271
Buse MG et al. Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats. 1975 Biochem. J. pmid:1200982
Schmidt-Wilcke HA et al. Effect of fatty acids on the stimulated gastric secretion in man. 1975 Digestion pmid:1201821
Tangen O et al. Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. 1975 Scand. J. Clin. Lab. Invest. pmid:1129590
Fulks RM et al. Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm. 1975 J. Biol. Chem. pmid:1141208
von Glutz G and Walter P Compartmentation of acetyl-coA in rat-liver mitochondria. 1975 Eur. J. Biochem. pmid:1204636
McDaniel HG Acute suppression of hepatic gluconeogenesis by glucose in the intact animal. 1975 Am. J. Physiol. pmid:1211489
Wilk PJ et al. Failure of intestinal lymphatic block to prevent experimental hypercholesterolemia. 1975 Lymphology pmid:1214506
Leovey EM and Andersen NH Molecular basis of prostaglandin potency. II. Proton NMR studies of the conformation of prostaglandin F2alpha. 1975 Prostaglandins pmid:1215541
Berne C The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. 1975 Biochem. J. pmid:776173
Glick MR et al. Glucose and octanoate utilization by isolated adult rat heart cells. 1974 Life Sci. pmid:4829540
Borbola J et al. Effects of octanoate on the electrical activity of Purkinje fibres. 1974 Experientia pmid:4824600
Hainaut J et al. Differentiation of antilymphocytic antibodies by analytical ion exchange chromatography: the effect of caprylic acid. 1974 Biomedicine pmid:4433656
Debeer LJ et al. Effects of octanoate and oleate on energy metabolism in the perfused rat liver. 1974 Eur. J. Biochem. pmid:4434997
Abidov AA and Isaev EI [The effect of strophanthin on caprylic acid oxidation in cardiac muscle in adrenaline myocarditis]. 1973 May-Jun Farmakol Toksikol pmid:4788489
Allary M and Saint-Blancard J [Use of sodium caprylate for the separation of plasma proteins]. 1973 Jul-Aug Ann Pharm Fr pmid:4793461
Wilson MB Control of phosphoenolpyruvate synthesis in guinea-pig mitochondria. 1973 Biochem. J. pmid:4724589