octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Hypertension, Portal D006975 12 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Critical Illness D016638 13 associated lipids
Endotoxemia D019446 27 associated lipids
Memory Disorders D008569 33 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Liver Failure D017093 5 associated lipids
Chickenpox D002644 1 associated lipids
Chylothorax D002916 1 associated lipids
Gastroparesis D018589 2 associated lipids
Gallstones D042882 3 associated lipids
Dyspepsia D004415 5 associated lipids
Snake Bites D012909 1 associated lipids
Prion Diseases D017096 2 associated lipids
Asthenia D001247 5 associated lipids
Esophageal Motility Disorders D015154 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Rosario P and Medina JM Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. 1980 Rev. Esp. Fisiol. pmid:7221165
Schenk J et al. [Irrigation treatment of concrements in the common bile duct with octanoate (Capmul 8210) (author's transl)]. 1980 Dtsch. Med. Wochenschr. pmid:7408673
May ME et al. Mechanism of the stimulation of branched chain oxoacid oxidation in liver by carnitine. 1980 J. Biol. Chem. pmid:7410370
Sugano T et al. Intracellular redox state and stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused rat liver. 1980 J. Biochem. pmid:7358625
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Kössler F et al. [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. V. Relations between twitch, tetanus and contracture]. 1980 Acta Biol. Med. Ger. pmid:7445906
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Bartels PD and Sestoft L Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. 1980 Biochim. Biophys. Acta pmid:7448206
Barth CA et al. Morphology and metabolism of adult rat hepatocytes in primary culture. 1980 Hoppe-Seyler's Z. Physiol. Chem. pmid:6997170
Caffier G et al. The influence of free fatty acids on functional properties of isolated skeletal muscles. Octanoate action on membrane resistance. 1980 Pflugers Arch. pmid:6966791
Kössler F et al. Octanol and octanoate induced inhibition of the mechanical activity of isolated frog skeletal muscles. 1980 Chem. Biol. Interact. pmid:6967777
Caffier G and Küchler G [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. IV. Effect of Na-octanoate on action potentials]. 1980 Acta Biol. Med. Ger. pmid:6969509
Sánchez-Serrano D et al. Enhancement of ouabain arrhythmias by fatty acids. 1980 J. Cardiovasc. Pharmacol. pmid:6156330
Chan SC Monitoring serum valproic acid by gas chromatography with electron-capture detection. 1980 Clin. Chem. pmid:6774836
Bijlsma R Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity. 1980 Biochem. Genet. pmid:6781470
Borg LA Effects of octanoate and ketone and bodies on the structure and function of isolated pancreatic islets in tissue culture. 1981 Acta Endocrinol. pmid:7010865
Rosario P and Medina JM Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. 1981 Rev. Esp. Fisiol. pmid:7244329
Henze K et al. The effect of hydrocortisone on cholesterol metabolism of cultured human skin fibroblasts. 1981 Biochim. Biophys. Acta pmid:6118180
Müller MJ et al. Effect of thyroid state on ketogenic capacity of the isolated perfused liver of starved rats. 1981 Biochim. Biophys. Acta pmid:6275888
Pegg DE et al. Metabolism of normal and ischemically injured rabbit kidneys during perfusion for 48 hours at 10 C. 1981 Transplantation pmid:7330963