| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Augustin K et al. | Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. | 2018 | Lancet Neurol | pmid:29263011 |
| Murtuza MI and Isokawa M | Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. | 2018 | J. Neurochem. | pmid:29063591 |
| Vacchina P et al. | Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. | 2018 | Exp. Parasitol. | pmid:29409741 |
| Saito K et al. | An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. | 2017 | Toxicol In Vitro | pmid:27965148 |
| Caviglia GP et al. | Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by 13C-octanoic Acid Breath Test. | 2017 | Minerva Med. | pmid:28707862 |
| Khabbush A et al. | Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. | 2017 | Epilepsia | pmid:28682459 |
| Kawai A et al. | Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. | 2017 | Biochim Biophys Acta Proteins Proteom | pmid:28473296 |
| Du J et al. | Molecular basis of P450 OleT: an investigation of substrate binding mechanism and major pathways. | 2017 | J. Comput. Aided Mol. Des. | pmid:28342136 |
| Besada-Lombana PB et al. | Engineering Saccharomyces cerevisiae fatty acid composition for increased tolerance to octanoic acid. | 2017 | Biotechnol. Bioeng. | pmid:28294288 |
| Lourenço A et al. | Antimicrobial treatments to control Listeria monocytogenes in queso fresco. | 2017 | Food Microbiol. | pmid:28213034 |
| Fontaine P et al. | Medium chain length polyhydroxyalkanoates biosynthesis in Pseudomonas putida mt-2 is enhanced by co-metabolism of glycerol/octanoate or fatty acids mixtures. | 2017 | Int. J. Biol. Macromol. | pmid:28174083 |
| Das K and Ghosh M | Structured DAG oil ameliorates renal injury in streptozotocin-induced diabetic rats through inhibition of NF-κB and activation of Nrf2 pathway. | 2017 | Food Chem. Toxicol. | pmid:28025123 |
| Vanheel H et al. | Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. | 2017 | Am. J. Gastroenterol. | pmid:27958284 |
| Clarke D et al. | Surface attachment of active antimicrobial coatings onto conventional plastic-based laminates and performance assessment of these materials on the storage life of vacuum packaged beef sub-primals. | 2017 | Food Microbiol. | pmid:27889148 |
| Jadhav A et al. | The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting. | 2017 | J Med Food | pmid:28922057 |
| Goussen C et al. | Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. | 2017 | BioDrugs | pmid:28508264 |
| Köllner S et al. | Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. | 2017 | Eur J Pharm Biopharm | pmid:28323109 |
| Andrade López JM et al. | Genetic basis of octanoic acid resistance in Drosophila sechellia: functional analysis of a fine-mapped region. | 2017 | Mol. Ecol. | pmid:28035709 |
| Peyser RD et al. | Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. | 2017 | Insect Mol. Biol. | pmid:28703934 |
| Hsieh CH et al. | The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. | 2017 | Biochemistry | pmid:28603981 |
| Centeno JA et al. | Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. | 2017 | Int. J. Food Microbiol. | pmid:28384620 |
| Alva-Murillo N et al. | Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization. | 2017 | Front Cell Infect Microbiol | pmid:28361042 |
| Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |
| Kandula M et al. | Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. | 2016 | Int. Immunopharmacol. | pmid:27716592 |
| Kateja N et al. | Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR). | 2016 | Biotechnol J | pmid:27447837 |
| Lemarié F et al. | Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. | 2016 | Biochim. Biophys. Acta | pmid:27317984 |
| Sawatani Y et al. | Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit. | 2016 | Bioorg. Med. Chem. | pmid:27301681 |
| Kubota K et al. | The molecular assembly of the ionic liquid/aliphatic carboxylic acid/aliphatic amine as effective and safety transdermal permeation enhancers. | 2016 | Eur J Pharm Sci | pmid:26965004 |
| Nakajima K et al. | Triterpenes suppress octanoylated ghrelin production in ghrelin-expressing human gastric carcinoma cells. | 2016 | Biomed. Res. | pmid:28003581 |
| Hogan S et al. | Eradication of Staphylococcus aureus Catheter-Related Biofilm Infections Using ML:8 and Citrox. | 2016 | Antimicrob. Agents Chemother. | pmid:27458213 |
| Lockman KA et al. | Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro. | 2016 | Lipids Health Dis | pmid:27368608 |
| Voller B et al. | Dose-escalation study of octanoic acid in patients with essential tremor. | 2016 | J. Clin. Invest. | pmid:26927672 |
| Diaz De Rienzo MA et al. | Effect of biosurfactants on Pseudomonas aeruginosa and Staphylococcus aureus biofilms in a BioFlux channel. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26825819 |
| Nishitani N et al. | Investigation on the Surface-Confined Self-Assembly Stabilized by Hydrogen Bonds of Urea and Amide Groups: Quantitative Analysis of Concentration Dependence of Surface Coverage. | 2015 | Chem Asian J | pmid:26033832 |
| Coronado MA et al. | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. | 2015 | Curr. Protein Pept. Sci. | pmid:25961401 |
| Pesce P et al. | Gastric and masticatory performances in full-arch immediate loading rehabilitated patients. | 2015 | J Oral Rehabil | pmid:25882620 |
| Kim SA and Rhee MS | Synergistic antimicrobial activity of caprylic acid in combination with citric acid against both Escherichia coli O157:H7 and indigenous microflora in carrot juice. | 2015 | Food Microbiol. | pmid:25846927 |
| RodrÃguez-Moyá M and Gonzalez R | Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. | 2015 | J Proteomics | pmid:25845584 |
| Chen Y et al. | Optimized mixed oils remarkably reduce the amount of surfactants in microemulsions without affecting oral bioavailability of ibuprofen by simultaneously enlarging microemulsion areas and enhancing drug solubility. | 2015 | Int J Pharm | pmid:25841571 |
| Damitz R and Chauhan A | Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery. | 2015 | Int J Pharm | pmid:25839419 |
| Royce LA et al. | Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity. | 2015 | Metab. Eng. | pmid:25839166 |
| Obeso JI et al. | The loss of function of PhaC1 is a survival mechanism that counteracts the stress caused by the overproduction of poly-3-hydroxyalkanoates in Pseudomonas putidaΔfadBA. | 2015 | Environ. Microbiol. | pmid:25627209 |
| Fu Y et al. | Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25620365 |
| Oiso S et al. | Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production. | 2015 | J Oleo Sci | pmid:26521811 |
| Fredrickson J et al. | The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model. | 2015 | J. Assist. Reprod. Genet. | pmid:26342329 |
| Kajimoto M et al. | Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26232235 |
| Lemarié F et al. | Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. | 2015 | PLoS ONE | pmid:26196391 |
| Genser B et al. | Within- and between-group regression for improving the robustness of causal claims in cross-sectional analysis. | 2015 | Environ Health | pmid:26159541 |
| Xu J et al. | In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis. | 2015 | Chem. Commun. (Camb.) | pmid:25792085 |
| Alonso C et al. | Skin delivery of antioxidant surfactants based on gallic acid and hydroxytyrosol. | 2015 | J. Pharm. Pharmacol. | pmid:25645286 |