| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Perera J et al. | Neuroprotective effects of alpha lipoic Acid on haloperidol-induced oxidative stress in the rat brain. | 2011 | Cell Biosci | pmid:21711768 |
| Ikemura K et al. | Design of a new, multi-purpose, light-curing adhesive comprising a silane coupling agent, acidic adhesive monomers and dithiooctanoate monomers for bonding to varied metal and dental ceramic materials. | 2011 | Dent Mater J | pmid:21778601 |
| Kumar KS et al. | Anticancer studies of drug encapsulated polyethylene terephthalate-Co-polylactic acid nanocapsules. | 2011 | J Pharm Bioallied Sci | pmid:21687360 |
| Gallis JL et al. | A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. | 2011 | Nutr Metab (Lond) | pmid:21676253 |
| Lim CT et al. | The expression of ghrelin O-acyltransferase (GOAT) in human tissues. | 2011 | Endocr. J. | pmid:21646729 |
| Brilli F et al. | Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction "time-of-flight" mass spectrometry (PTR-TOF). | 2011 | PLoS ONE | pmid:21637822 |
| Best L et al. | A dual action of saturated fatty acids on electrical activity in rat pancreatic β-cells. Role of volume-regulated anion channel and KATP channel currents. | 2011 | J. Physiol. (Lond.) | pmid:21242256 |
| Novaretti MC and Dinardo CL | Immunoglobulin: production, mechanisms of action and formulations. | 2011 | Rev Bras Hematol Hemoter | pmid:23049343 |
| Kaiya H et al. | Ghrelin Receptor in Two Species of Anuran Amphibian, Bullfrog (Rana catesbeiana), and Japanese Tree Frog (Hyla japonica). | 2011 | Front Endocrinol (Lausanne) | pmid:22654801 |
| Andrén-Sandberg A | Pancreatic cancer: chemotherapy and radiotherapy. | 2011 | N Am J Med Sci | pmid:22540056 |
| Schmidt SP et al. | Toxic response caused by a misfolding variant of the mitochondrial protein short-chain acyl-CoA dehydrogenase. | 2011 | J. Inherit. Metab. Dis. | pmid:21170680 |
| Cheng J et al. | Synthesis of dendrigraft poly(ϵ-caprolactone)s using side hydroxyl groups for the grafting of branch chains. | 2011 | Macromol Rapid Commun | pmid:21928304 |
| Goldstein JL et al. | Surviving starvation: essential role of the ghrelin-growth hormone axis. | 2011 | Cold Spring Harb. Symp. Quant. Biol. | pmid:21785007 |
| Choi MH et al. | Metabolic relationship between polyhydroxyalkanoic acid and rhamnolipid synthesis in Pseudomonas aeruginosa: comparative ¹³C NMR analysis of the products in wild-type and mutants. | 2011 | J. Biotechnol. | pmid:21029757 |
| Whang J and Gwak H | Effects of amines on percutaneous absorption of alendronate. | 2011 | Drug Dev Ind Pharm | pmid:21126206 |
| Keller J et al. | A modified ¹³C-mixed triglyceride breath test detects moderate pancreatic exocrine insufficiency. | 2011 | Pancreas | pmid:21705945 |
| Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
| Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
| Bondia-Pons I et al. | Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. | 2011 | Nutr J | pmid:22011443 |
| Salimon J et al. | Synthesis and physical properties of estolide ester using saturated Fatty Acid and ricinoleic Acid. | 2011 | J Autom Methods Manag Chem | pmid:22007150 |
| Wittgens A et al. | Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440. | 2011 | Microb. Cell Fact. | pmid:21999513 |
| Frago LM et al. | Neuroprotective actions of ghrelin and growth hormone secretagogues. | 2011 | Front Mol Neurosci | pmid:21994488 |
| Henderson ST and Poirier J | Pharmacogenetic analysis of the effects of polymorphisms in APOE, IDE and IL1B on a ketone body based therapeutic on cognition in mild to moderate Alzheimer's disease; a randomized, double-blind, placebo-controlled study. | 2011 | BMC Med. Genet. | pmid:21992747 |
| Shimshoni JA et al. | Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. | 2011 | Biochim. Biophys. Acta | pmid:21184843 |
| Valipe SR et al. | In vitro antimicrobial properties of caprylic acid, monocaprylin, and sodium caprylate against Dermatophilus congolensis. | 2011 | Am. J. Vet. Res. | pmid:21355735 |
| Sato S et al. | Expression and characterization of (R)-specific enoyl coenzyme A hydratases making a channeling route to polyhydroxyalkanoate biosynthesis in Pseudomonas putida. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21327961 |
| Cardeñosa V et al. | Generalized and rapid supramolecular solvent-based sample treatment for the determination of annatto in food. | 2011 | J Chromatogr A | pmid:22071422 |
| Duarte JM et al. | Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T. | 2011 | Front Neuroenergetics | pmid:21713114 |
| Hines JD et al. | Inappropriate use of D-values for determining biocidal activity of various antimicrobials. | 2011 Jan-Feb | J. Food Sci. | pmid:21535698 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
| Brun AC et al. | The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. | 2012 | Clin Nutr | pmid:21835514 |
| Hämmerle SP et al. | The single dose pharmacokinetic profile of a novel oral human parathyroid hormone formulation in healthy postmenopausal women. | 2012 | Bone | pmid:22289659 |
| Vargas M et al. | Purification of IgG and albumin from human plasma by aqueous two phase system fractionation. | 2012 | Biotechnol. Prog. | pmid:22619188 |
| Barnette D et al. | Pathogen safety profile of a 10% IgG preparation manufactured using a depth filtration-modified process. | 2012 | Biologicals | pmid:22579294 |
| Fernández J et al. | Synthesis, structure and properties of poly(L-lactide-co-ε-caprolactone) statistical copolymers. | 2012 | J Mech Behav Biomed Mater | pmid:22498288 |
| Lockman KA et al. | Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. | 2012 | Liver Int. | pmid:22429485 |
| Cordes AA et al. | Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. | 2012 | J Pharm Sci | pmid:22422106 |
| Calandra P et al. | Emerging dynamics in surfactant-based liquid mixtures: octanoic acid/bis(2-ethylhexyl) amine systems. | 2012 | J Chem Phys | pmid:22360203 |
| Yahashi S et al. | GHRP-6 mimics ghrelin-induced stimulation of food intake and suppression of locomotor activity in goldfish. | 2012 | Peptides | pmid:22349352 |
| Tan CH et al. | Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. | 2012 | Acta Trop. | pmid:22322247 |
| Ryu JK and Yoo SD | Preparation and evaluation of bicyclol microemulsions for enhanced oral bioavailability. | 2012 | Drug Dev Ind Pharm | pmid:22283588 |
| Maricic MJ | Oral calcitonin. | 2012 | Curr Osteoporos Rep | pmid:22281725 |
| Solano S et al. | Low pH formulation of whole IgG antivenom: impact on quality, safety, neutralizing potency and viral inactivation. | 2012 | Biologicals | pmid:22266304 |
| Cordes AA et al. | Selective domain stabilization as a strategy to reduce fusion protein aggregation. | 2012 | J Pharm Sci | pmid:22234888 |
| Escapa IF et al. | The polyhydroxyalkanoate metabolism controls carbon and energy spillage in Pseudomonas putida. | 2012 | Environ. Microbiol. | pmid:22225632 |
| Wang CH et al. | Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. | 2012 | Biomacromolecules | pmid:22145634 |
| Harada E et al. | Functional evolution of duplicated odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. | 2012 | PLoS ONE | pmid:22238638 |
| Molinas A et al. | Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium. | 2012 | PLoS ONE | pmid:22563480 |
| Pereira RF et al. | What drives the precipitation of long-chain calcium carboxylates (soaps) in aqueous solution? | 2012 | Phys Chem Chem Phys | pmid:22513819 |
| Rucinski M et al. | Evidence suggesting that ghrelin O-acyl transferase inhibitor acts at the hypothalamus to inhibit hypothalamo-pituitary-adrenocortical axis function in the rat. | 2012 | Peptides | pmid:22543218 |
| Can Güven S and Laska M | Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. | 2012 | PLoS ONE | pmid:22479594 |
| Poblete-Castro I et al. | The metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single- and multiple-nutrient-limited growth: highlights from a multi-level omics approach. | 2012 | Microb. Cell Fact. | pmid:22433058 |
| Mukabana WR et al. | A novel synthetic odorant blend for trapping of malaria and other African mosquito species. | 2012 | J. Chem. Ecol. | pmid:22426893 |
| Vazquez-Cruz MA et al. | Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans). | 2012 | J. Food Sci. | pmid:22429085 |
| Gschwind HP et al. | Metabolism and disposition of the oral absorption enhancer 14C-radiolabeled 8-(N-2-hydroxy-5-chlorobenzoyl)-amino-caprylic acid (5-CNAC) in healthy postmenopausal women and supplementary investigations in vitro. | 2012 | Eur J Pharm Sci | pmid:22579664 |
| Ferreira BS et al. | A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils. | 2012 | ScientificWorldJournal | pmid:22593692 |
| Brodsky Y et al. | Caprylic acid precipitation method for impurity reduction: an alternative to conventional chromatography for monoclonal antibody purification. | 2012 | Biotechnol. Bioeng. | pmid:22549395 |
| Ohgusu H et al. | Enzymatic characterization of GOAT, ghrelin O-acyltransferase. | 2012 | Meth. Enzymol. | pmid:22975052 |
| Matsumoto N and Nakazato M | Clinical application of ghrelin for chronic respiratory diseases. | 2012 | Meth. Enzymol. | pmid:22975067 |
| Simon-Colin C et al. | Biosynthesis and characterization of polyhydroxyalkanoates by Pseudomonas guezennei from alkanoates and glucose. | 2012 | Int. J. Biol. Macromol. | pmid:22947450 |
| Ogungbenro K and Aarons L | A semi-mechanistic gastric emptying pharmacokinetic model for (13)C-octanoic acid: an evaluation using simulation. | 2012 | Eur J Pharm Sci | pmid:22155547 |
| Otero-Patiño R et al. | Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. | 2012 | Toxicon | pmid:22146491 |
| Wlaź P et al. | Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice. | 2012 | Neuropharmacology | pmid:22210332 |
| Morrill KM et al. | Estimate of colostral immunoglobulin G concentration using refractometry without or with caprylic acid fractionation. | 2012 | J. Dairy Sci. | pmid:22720953 |
| Janssen S et al. | Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. | 2012 | PLoS ONE | pmid:22768248 |
| Kovalchuk NM et al. | Ionic strength and pH as control parameters for spontaneous surface oscillations. | 2012 | Langmuir | pmid:22480181 |
| Hu JY et al. | Residue determination and dissipation of ioxynil octanoate in maize and soil. | 2012 | J Environ Sci Health B | pmid:22424062 |
| Librán-Pérez M et al. | Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22496361 |
| Zhang JH et al. | High-throughput screening of B factor saturation mutated Rhizomucor miehei lipase thermostability based on synthetic reaction. | 2012 | Enzyme Microb. Technol. | pmid:22500900 |
| Nahab FB et al. | Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. | 2012 | Neurotherapeutics | pmid:22454323 |
| Ogawa N et al. | Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. | 2012 | Metab. Clin. Exp. | pmid:22445513 |
| Tetrick MA et al. | Octanoate and nonaoate oxidation increases 50-80% over the first two days of life in piglet triceps brachii and gracilis muscle strips. | 2012 | J. Nutr. | pmid:22513984 |
| Kollanoor-Johny A et al. | Caprylic acid reduces Salmonella Enteritidis populations in various segments of digestive tract and internal organs of 3- and 6-week-old broiler chickens, therapeutically. | 2012 | Poult. Sci. | pmid:22700516 |
| Becerra-Dórame MJ et al. | Production response and digestive enzymatic activity of the Pacific white shrimp Litopenaeus vannamei (Boone, 1931) intensively pregrown in microbial heterotrophic and autotrophic-based systems. | 2012 | ScientificWorldJournal | pmid:22649317 |
| Shi S et al. | Self-assembled mPEG-PCL-g-PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro. | 2012 | Int J Nanomedicine | pmid:22619525 |
| Abdolmohammadi S et al. | Enhancement of mechanical and thermal properties of polycaprolactone/chitosan blend by calcium carbonate nanoparticles. | 2012 | Int J Mol Sci | pmid:22605993 |
| Kube M et al. | Current view on phytoplasma genomes and encoded metabolism. | 2012 | ScientificWorldJournal | pmid:22550465 |
| Wood P | Human normal immunoglobulin in the treatment of primary immunodeficiency diseases. | 2012 | Ther Clin Risk Manag | pmid:22547934 |
| Li J et al. | Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts. | 2012 | PLoS ONE | pmid:22529899 |
| Kim JW | Could carbon breath test measurement accurately reflect gastric emptying of liquid nutrient meal in the critically ill patients? (Gut 2011;60:1336-1343). | 2012 | J Neurogastroenterol Motil | pmid:22523735 |
| Delporte C | Recent advances in potential clinical application of ghrelin in obesity. | 2012 | J Obes | pmid:22523666 |
| Park S et al. | Development of sandwich enzyme-linked immunosorbent assay for the detection of Cronobacter muytjensii (formerly called Enterobacter sakazakii). | 2012 | Microbiol. Immunol. | pmid:22519814 |
| Liang QH et al. | Ghrelin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the ERK pathway. | 2012 | PLoS ONE | pmid:22514603 |
| Lin HV et al. | Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. | 2012 | PLoS ONE | pmid:22506074 |
| Li RL et al. | Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids. | 2012 | J. Biol. Chem. | pmid:22474325 |
| Nejati K and Zabihi R | Preparation and magnetic properties of nano size nickel ferrite particles using hydrothermal method. | 2012 | Chem Cent J | pmid:22462726 |
| Lu J et al. | A molecular mechanism for modulating plasma Zn speciation by fatty acids. | 2012 | J. Am. Chem. Soc. | pmid:22239162 |
| Andersen JT et al. | Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. | 2012 | Nat Commun | pmid:22215085 |
| Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
| MaletÃnská L et al. | Characterization of new stable ghrelin analogs with prolonged orexigenic potency. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22182933 |
| Nóbrega AC et al. | Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. | 2012 | BMC Gastroenterol | pmid:23216812 |
| Riniker S et al. | Temperature dependence of the dielectric permittivity of acetic acid, propionic acid and their methyl esters: a molecular dynamics simulation study. | 2012 | Chemphyschem | pmid:22383366 |
| Takatani-Nakase T et al. | Transcutaneous immunization system using a hydrotropic formulation induces a potent antigen-specific antibody response. | 2012 | PLoS ONE | pmid:23110149 |
| Faria M et al. | Surface Characterization of Asymmetric Bi-Soft Segment Poly(ester urethane urea) Membranes for Blood-Oxygenation Medical Devices. | 2012 | Int J Biomater | pmid:22164163 |
| Ishida T et al. | Base-free direct oxidation of 1-octanol to octanoic acid and its octyl ester over supported gold catalysts. | 2012 | ChemSusChem | pmid:23065901 |
| Layek B and Singh J | N-hexanoyl, N-octanoyl and N-decanoyl chitosans: Binding affinity, cell uptake, and transfection. | 2012 | Carbohydr Polym | pmid:24750737 |
| Goh YS and Tan IK | Polyhydroxyalkanoate production by antarctic soil bacteria isolated from Casey Station and Signy Island. | 2012 | Microbiol. Res. | pmid:21945102 |
| Chang P et al. | The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. | 2012 | Dis Model Mech | pmid:21876211 |
| Prajapati HN et al. | A comparative evaluation of mono-, di- and triglyceride of medium chain fatty acids by lipid/surfactant/water phase diagram, solubility determination and dispersion testing for application in pharmaceutical dosage form development. | 2012 | Pharm. Res. | pmid:21861203 |
| Mohan A et al. | Role of peroxyacetic acid, octanoic acid, malic acid, and potassium lactate on the microbiological and instrumental color characteristics of ground beef. | 2012 | J. Food Sci. | pmid:22352902 |