octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Skin Diseases, Bacterial D017192 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Reye Syndrome D012202 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Webb T Identification of interference affecting the gas-liquid chromatography analysis of valproic acid in quality control material. 1986 Pathology pmid:3097616
Chacín J et al. Role of calcium in secretory and metabolic effects of substrates in the gastric mucosa. 1986 Am. J. Physiol. pmid:3090895
Patel TB Effect of sulfonylureas on hepatic fatty acid oxidation. 1986 Am. J. Physiol. pmid:3090894
Nau H and Löscher W Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice. 1986 Fundam Appl Toxicol pmid:3086174
Taylor WM et al. The stimulation of tricarboxylic acid-cycle flux by alpha-adrenergic agonists in perfused rat liver. 1986 Biochem. J. pmid:3082324
Veerkamp JH et al. An accurate and sensitive assay of [14C]octanoate oxidation and its application on tissue homogenates and fibroblasts. 1986 Biochim. Biophys. Acta pmid:3081042
Merrill AR et al. Effects of exogenous fatty acids on calcium uptake by brush-border membrane vesicles from rabbit small intestine. 1986 Biochim. Biophys. Acta pmid:3081028
Whyte RK et al. Excretion of dicarboxylic and omega-1 hydroxy fatty acids by low birth weight infants fed with medium-chain triglycerides. 1986 Pediatr. Res. pmid:3080726
Jones DB et al. Hepatic encephalopathy. Application of visual evoked responses to test hypotheses of its pathogenesis in rats. 1987 J. Hepatol. pmid:3033057
Harris RA et al. Regulation of branched-chain alpha-ketoacid dehydrogenase complex by covalent modification. 1986 Adv. Enzyme Regul. pmid:3028049
Connolly E et al. Norepinephrine-induced Na+ influx in brown adipocytes is cyclic AMP-mediated. 1986 J. Biol. Chem. pmid:3021738
Ayuso MS et al. Interrelation between gluconeogenesis and hepatic protein synthesis. 1986 Biochim. Biophys. Acta pmid:3015233
Lohse MJ et al. Effects of temperature and membrane phase transitions on ligand binding to alpha 2-receptors of human platelets. 1986 Mol. Pharmacol. pmid:3005830
Carr C and Morrison DC Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes. 1985 Infect. Immun. pmid:2989182
Polácek H et al. Study of cough in anaesthetized cats with experimental pulmonary oedema. 1986 Physiol Bohemoslov pmid:2950532
Kuhara T et al. Identification and quantification of octanoyl glucuronide in the urine of children who ingested medium-chain triglycerides. 1986 Biomed. Environ. Mass Spectrom. pmid:2948585
Vacchina P et al. Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. 2018 Exp. Parasitol. pmid:29409741
Kössler F et al. Depressive effects of free fatty acids on the development of tension in different muscle types. 1986 Biomed. Biochim. Acta pmid:2938577
Remy-Heintz N and Bali JP [Demonstration of glycoprotein antigens associated with stomach tumors]. 1985 C. R. Seances Soc. Biol. Fil. pmid:2935234
Rybczynska M and Csordas A Chain length-dependent interaction of free fatty acids with the erythrocyte membrane. 1989 Life Sci. pmid:2927261
Augustin K et al. Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. 2018 Lancet Neurol pmid:29263011
Brass EP and Garrity MJ Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. 1989 Biochim. Biophys. Acta pmid:2912505
Van Hoogdalem EJ et al. The influence of components on the rectal absorption of cefazolin in rats. 1988 J. Pharm. Pharmacol. pmid:2907567
Murtuza MI and Isokawa M Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. 2018 J. Neurochem. pmid:29063591
Kato A and Iwata S Studies on improved corneal permeability to bunazosin. 1988 J. Pharmacobio-dyn. pmid:2902207
Kato A and Iwata S Corneal permeability to bunazosin in rabbits. 1988 J. Pharmacobio-dyn. pmid:2900888
Reichmann H et al. Enzymes of fatty acid beta-oxidation in developing brain. 1988 J. Neurochem. pmid:2899130
Kato A and Iwata S In vitro study on corneal permeability to bunazosin. 1988 J. Pharmacobio-dyn. pmid:2898016
Moore KH et al. Hepatic hydrolysis of octanoyl-CoA and valproyl-CoA in control and valproate-fed animals. 1988 Int. J. Biochem. pmid:2895026
Ishizawa T et al. Enhancement of jejunal and colonic absorption of fosfomycin by promoters in the rat. 1987 J. Pharm. Pharmacol. pmid:2892912
Jadhav A et al. The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting. 2017 J Med Food pmid:28922057
Forest C et al. A preadipocyte clonal line from mouse brown adipose tissue. Short- and long-term responses to insulin and beta-adrenergics. 1987 Exp. Cell Res. pmid:2877896
Caviglia GP et al. Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by 13C-octanoic Acid Breath Test. 2017 Minerva Med. pmid:28707862
Peyser RD et al. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. 2017 Insect Mol. Biol. pmid:28703934
Khabbush A et al. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. 2017 Epilepsia pmid:28682459
Thomas JD et al. The carboxylic and amino acid chemoreception niche of Bulinus rohlfsi (Clessin), the snail host of Schistosoma haematobium. 1985 Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. pmid:2865079
Oberhaensli RD et al. Effect of norepinephrine on ketogenesis, fatty acid oxidation, and esterification in isolated rat hepatocytes. 1985 Diabetes pmid:2862086
Hsieh CH et al. The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. 2017 Biochemistry pmid:28603981
Goussen C et al. Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. 2017 BioDrugs pmid:28508264
Ando Y et al. Synthesis of acylated SOD derivatives which bind to the biomembrane lipid surface and dismutate extracellular superoxide radicals. 1988 FEBS Lett. pmid:2847946
Kawai A et al. Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. 2017 Biochim Biophys Acta Proteins Proteom pmid:28473296
Connolly E and Nedergaard J Beta-adrenergic modulation of Ca2+ uptake by isolated brown adipocytes. Possible involvement of mitochondria. 1988 J. Biol. Chem. pmid:2839496
Centeno JA et al. Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. 2017 Int. J. Food Microbiol. pmid:28384620
Alva-Murillo N et al. Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization. 2017 Front Cell Infect Microbiol pmid:28361042
Du J et al. Molecular basis of P450 OleT: an investigation of substrate binding mechanism and major pathways. 2017 J. Comput. Aided Mol. Des. pmid:28342136
Köllner S et al. Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. 2017 Eur J Pharm Biopharm pmid:28323109
Barbee RW et al. T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats. 1988 Am. J. Physiol. pmid:2830793
Besada-Lombana PB et al. Engineering Saccharomyces cerevisiae fatty acid composition for increased tolerance to octanoic acid. 2017 Biotechnol. Bioeng. pmid:28294288
Baraldi M et al. An increase in cerebral benzodiazepine receptors induced by a subacute administration of ammonia, mercaptans and short-chain fatty acids in rats. 1987 Clin. Sci. pmid:2826071
Widebäck K Binding of albumin fragments to surface receptor in A, C, and G streptococci. 1987 Acta Pathol Microbiol Immunol Scand B pmid:2823527