| MeSH term | MeSH ID | Detail |
|---|---|---|
| Skin Diseases, Bacterial | D017192 | 8 associated lipids |
| Infant, Newborn, Diseases | D007232 | 9 associated lipids |
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
| Amyotrophic Lateral Sclerosis | D000690 | 11 associated lipids |
| Hypertension, Portal | D006975 | 12 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Critical Illness | D016638 | 13 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
octanoic acid
octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.
Cross Reference
Introduction
To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with octanoic acid?
octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with octanoic acid
PubChem Associated disorders and diseases
What pathways are associated with octanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with octanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with octanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with octanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with octanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with octanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with octanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Becerra-Dórame MJ et al. | Production response and digestive enzymatic activity of the Pacific white shrimp Litopenaeus vannamei (Boone, 1931) intensively pregrown in microbial heterotrophic and autotrophic-based systems. | 2012 | ScientificWorldJournal | pmid:22649317 |
| Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
| Plante OJ et al. | Automated solid-phase synthesis of oligosaccharides. | 2001 | Science | pmid:11222853 |
| Yamada M et al. | A medium-chain fatty acid as an alternative energy source in mouse preimplantation development. | 2012 | Sci Rep | pmid:23226596 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
| Zimmermann S et al. | Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. | 2012 Jan-Mar | Sci Pharm | pmid:22396915 |
| Clegg ME and Shafat A | Procedures in the 13C octanoic acid breath test for measurement of gastric emptying: analysis using Bland-Altman methods. | 2010 | Scand. J. Gastroenterol. | pmid:20443742 |
| Hope HB et al. | Reduced ¹³C-D-xylose absorption in alcoholics is more likely caused by alterations in small intestinal mucosa than delayed gastric emptying. | 2011 | Scand. J. Gastroenterol. | pmid:21275757 |
| Sugiyama E et al. | Desirable pharmacokinetic properties of (13)C-uracil as a breath test probe of gastric emptying in comparison with (13)C-acetate and (13)C-octanoate in rats. | 2009 | Scand. J. Gastroenterol. | pmid:19585373 |
| Skrede S and Slaattelid O | Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. | 1979 | Scand. J. Clin. Lab. Invest. | pmid:531496 |
| Tangen O et al. | Platelet reactivity ex vivo and in vivo after acute and chronic treatment with sodium caprylate. | 1975 | Scand. J. Clin. Lab. Invest. | pmid:1129590 |
| Andres T et al. | Brain edema in acute liver failure. Insight from experimental studies. | 1990 | Rev. Invest. Clin. | pmid:19256151 |
| Guimbretiere J et al. | [A further case of albumin auto-agglutination in a blood donor]. | 1976 | Rev. Fr. Transfus. Immunohematol. | pmid:824703 |
| Reuge C | [Enzymatic determination of caprylates in protein preparations]. | 1982 | Rev. Fr. Transfus. Immunohematol. | pmid:7163732 |
| Blatrix C et al. | [Properties of and information about a new preparation of immunoglobulins (IgGAM) enriched in IgA and IgM]. | 1977 | Rev. Fr. Transfus. Immunohematol. | pmid:918496 |
| Lambin P and Debbia M | [IgG4 levels in polyvalent immunoglobulins and immunoglobulins prepared by precipitation with caprylic acid]. | 1986 Oct-Nov | Rev. Fr. Transfus. Immunohematol. | pmid:3576044 |
| Valdivia MM et al. | [Effect of octanoic acid on the insulin secretion in response to glucose in vitro (author's transl)]. | 1979 | Rev. Esp. Fisiol. | pmid:504776 |
| Rosario P and Medina JM | Effect of gluconeogenic substrates on ketogenesis in isolated rat hepatocytes. I. Effect of glycerol. | 1980 | Rev. Esp. Fisiol. | pmid:7221165 |
| Rosario P and Medina JM | Antiketogenic effect of gluconeogenic substrates. II. Effect of pyruvate. | 1981 | Rev. Esp. Fisiol. | pmid:7244329 |
| Leite-Moreira AF et al. | Modulation of myocardial function by pyruvate. | 2002 | Rev Port Cardiol | pmid:12090129 |
| González A et al. | [Applications of stable isotopes in biomedical sciences]. | 1998 Apr-Jun | Rev Med Univ Navarra | pmid:10420942 |
| González A et al. | [Studying of gastric emptying for solids and liquids by means of using stable isotopes]. | 1998 Apr-Jun | Rev Med Univ Navarra | pmid:10420944 |
| Sfarti C et al. | [Prevalence of delayed gastric emptying of solids in functional dyspepsia and its relationship to symptoms]. | 2009 Oct-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:20191871 |
| Germán JC et al. | [Solvent effects on cholesterol calculi: an in vitro study using octanoic acid, glycerol monooctanate, sodium cholate, heparin and ursodeoxycholic acid]. | 1985 | Rev Esp Enferm Apar Dig | pmid:3975461 |
| HIRSCH HM and WALLACE GI | The octanoxidase system of Streptomyces aureofaciens. | 1951 | Rev Can Biol | pmid:14865337 |
| Novaretti MC and Dinardo CL | Immunoglobulin: production, mechanisms of action and formulations. | 2011 | Rev Bras Hematol Hemoter | pmid:23049343 |
| Auriol S et al. | Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit. | 2013 | Retina (Philadelphia, Pa.) | pmid:22902566 |
| Angelos MG et al. | Glucose, insulin and potassium (GIK) during reperfusion mediates improved myocardial bioenergetics. | 2002 | Resuscitation | pmid:12458070 |
| Kojima M and Kangawa K | Ghrelin: from gene to physiological function. | 2010 | Results Probl Cell Differ | pmid:19859676 |
| Wyse CA et al. | A comparison of the rate of recovery of 13CO2 in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog. | 2003 | Res. Vet. Sci. | pmid:12589736 |
| Wyse CA et al. | The(13)C-octanoic acid breath test for detection of effects of meal composition on the rate of solid-phase gastric emptying in ponies. | 2001 | Res. Vet. Sci. | pmid:11666152 |
| Schmeisch AP et al. | The role of hemodynamics in the action of diltiazem on hepatic fatty acid metabolism. | 1998 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:10342914 |
| Burns AH and Reddy WJ | Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. | 1981 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6267674 |
| Derr RF and Draves K | Methanethiol metabolism in the rat. | 1983 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6407074 |
| Mitkov D et al. | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. | 1989 | Res Exp Med (Berl) | pmid:2813970 |
| O'Brien M et al. | Ghrelin in the human myometrium. | 2010 | Reprod. Biol. Endocrinol. | pmid:20509935 |
| Duée PH et al. | Development and regulation of ketogenesis in isolated hepatocytes from newborn rabbits. | 1985 | Reprod Nutr Dev | pmid:3992001 |
| Aurousseau B et al. | [Effect of the replacement of a part of the tallow in a milk supply with tricaprylin or coconut oil on the use of energy and nitrogen by the preruminant calf]. | 1984 | Reprod Nutr Dev | pmid:6729239 |
| Ma J et al. | Effects of cefaclor on gastric emptying and cholecystokinin release in healthy humans. | 2010 | Regul. Pept. | pmid:19914303 |
| Hlongwane C et al. | Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11675670 |
| Parshintsev J et al. | Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26395607 |
| Jackson SJ et al. | Use of isotopically labelled octanoic acid to assess the effect of meal size on gastric emptying. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15150821 |
| Nebbioso A et al. | Limitations of electrospray ionization in the analysis of a heterogeneous mixture of naturally occurring hydrophilic and hydrophobic compounds. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20941764 |
| Bluck LJ et al. | Measurement of gastric emptying in man using deuterated octanoic acid. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11754258 |
| Kim DJ et al. | Structural basis of octanoic acid recognition by lipoate-protein ligase B. | 2008 | Proteins | pmid:18076036 |
| Raza S et al. | Enantioselectivity in Candida antarctica lipase B: a molecular dynamics study. | 2001 | Protein Sci. | pmid:11266619 |
| Midelfort KS et al. | Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. | 2013 | Protein Eng. Des. Sel. | pmid:23012440 |
| Leovey EM and Andersen NH | Molecular basis of prostaglandin potency. II. Proton NMR studies of the conformation of prostaglandin F2alpha. | 1975 | Prostaglandins | pmid:1215541 |
| Socała K et al. | Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25455587 |
| Wlaź P et al. | Acute anticonvulsant effects of capric acid in seizure tests in mice. | 2015 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:25445478 |