octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Skin Diseases, Bacterial D017192 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Biliary Fistula D001658 13 associated lipids
Critical Illness D016638 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Reye Syndrome D012202 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Al-Abdulla I et al. Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid. 2014 J. Immunol. Methods pmid:24246428
Kajimoto M et al. Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. 2014 Am. J. Physiol. Heart Circ. Physiol. pmid:24531815
Darling RA et al. Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760994
Zurich MG et al. Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. 2013 Toxicol In Vitro pmid:22954530
Auriol S et al. Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit. 2013 Retina (Philadelphia, Pa.) pmid:22902566
Nguyen NQ et al. Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy. 2013 Intensive Care Med pmid:23471513
Bauchart-Thevret C et al. Supplementing monosodium glutamate to partial enteral nutrition slows gastric emptying in preterm pigs(1-3). 2013 J. Nutr. pmid:23446960
Brun AC et al. Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals. 2013 Clin Nutr pmid:23196118
Midelfort KS et al. Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. 2013 Protein Eng. Des. Sel. pmid:23012440
Bruno G et al. 13C-octanoic acid breath test to study gastric emptying time. 2013 Eur Rev Med Pharmacol Sci pmid:24443070
Librán-Pérez M et al. Response of hepatic lipid and glucose metabolism to a mixture or single fatty acids: Possible presence of fatty acid-sensing mechanisms. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23010243
Librán-Pérez M et al. Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. 2013 PLoS ONE pmid:23533628
Librán-Pérez M et al. In vitro response of putative fatty acid-sensing systems in rainbow trout liver to increased levels of oleate or octanoate. 2013 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:23542747
Creedon CT et al. Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test. 2013 J Vis Exp pmid:23542813
Alva-Murillo N et al. Effects of sodium octanoate on innate immune response of mammary epithelial cells during Staphylococcus aureus internalization. 2013 Biomed Res Int pmid:23509807
Yang Y and McClements DJ Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. 2013 J Colloid Interface Sci pmid:23768725
Corona-Castañeda B et al. Modulators of antibiotic activity from Ipomoea murucoides. 2013 Phytochemistry pmid:23920226
de Oliveira AL et al. Adrenergic metabolic and hemodynamic effects of octopamine in the liver. 2013 Int J Mol Sci pmid:24196353
Hungate EA et al. A locus in Drosophila sechellia affecting tolerance of a host plant toxin. 2013 Genetics pmid:24037270
Kursu VA et al. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. 2013 Mol. Microbiol. pmid:24102902