octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Skin Diseases, Bacterial D017192 8 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Hypertension, Portal D006975 12 associated lipids
Crohn Disease D003424 12 associated lipids
Critical Illness D016638 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Reye Syndrome D012202 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Cha BS et al. Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPARgamma agonists. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15727952
Sakata I et al. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19401456
Tham E et al. Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19240252
Bando M et al. Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22114024
Turcotte LP et al. High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11739099
Jørgensen J and Mortensen PB Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11447021
Mizutani M et al. Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501445
Barron JT and Gu L Energetic effects of adenosine on vascular smooth muscle. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10644580
Panchal AR et al. Partitioning of pyruvate between oxidation and anaplerosis in swine hearts. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11045976
Longnus SL et al. Regulation of myocardial fatty acid oxidation by substrate supply. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557544
Allard MF et al. AMPK and metabolic adaptation by the heart to pressure overload. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:16920812
Labarthe F et al. Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. 2005 Am. J. Physiol. Heart Circ. Physiol. pmid:15550523
Vincent G et al. Differential modulation of citrate synthesis and release by fatty acids in perfused working rat hearts. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:12933348
Kajimoto M et al. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26232235
Kajimoto M et al. Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo. 2014 Am. J. Physiol. Heart Circ. Physiol. pmid:24531815
Battiprolu PK et al. Sex differences in energy metabolism and performance of teleost cardiac tissue. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17038442
Richards JG et al. Palmitate movement across red and white muscle membranes of rainbow trout. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12969874
El Hafidi M et al. Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats. 2004 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:15331379
Librán-Pérez M et al. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. 2012 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:22496361
Sallam HS et al. Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20427716