octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Skin Diseases, Bacterial D017192 8 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hepatic Encephalopathy D006501 9 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Crohn Disease D003424 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Critical Illness D016638 13 associated lipids
Biliary Fistula D001658 13 associated lipids
Campylobacter Infections D002169 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Carrington MJ et al. Octanoate and palmitate as substrates for ketogenesis by hepatocytes isolated from suckling rabbits. 1981 Biochem. Soc. Trans. pmid:7215663
Parameswaran M and Arinze IJ Phosphoenolpyruvate synthesis by fetal guinea-pig liver mitochondria. 1981 Biochim. Biophys. Acta pmid:7225415
Balint JA et al. Desaturation of endogenous and exogenous palmitate in lung tissue in vitro. 1981 Lipids pmid:7300595
Kragh-Hansen U Effects of aliphatic fatty acids on the binding of Phenol Red to human serum albumin. 1981 Biochem. J. pmid:7316975
Bauché F et al. 2-Mercaptoacetate administration depresses the beta-oxidation pathway through an inhibition of long-chain acyl-CoA dehydrogenase activity. 1981 Biochem. J. pmid:7317017
Ebbesen F and Brodersen R Albumin administration combined with phototherapy in treatment of hyperbilirubinaemia in low-birth-weight infants. 1981 Acta Paediatr Scand pmid:7324912
Einarsson M et al. Removal of hepatitis B virus from a concentrate of coagulation factors II, VII, IX and X by hydrophobic interaction chromatography. 1981 J. Virol. Methods pmid:7328163
Kaler LW and Neaves WB The steroidogenic capacity of the aging rat testis. 1981 J Gerontol pmid:7252069
Dimenna GP and Emery RS Palmitate and octanoate metabolism in bovine mammary tissue. 1981 J. Dairy Sci. pmid:7264015
Wells JW et al. The biosynthesis of progesterone by fowl granulosa cells in vitro from 14C-labelled substrates. 1981 J. Steroid Biochem. pmid:7265968
Trauner DA and Adams H Intracranial pressure elevations during octanoate infusion in rabbits: an experimental model of Reye's syndrome. 1981 Pediatr. Res. pmid:7267183
Ferré P et al. Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats. 1981 Biochem. J. pmid:7340842
Felix R and Fleisch H Increase in fatty acid oxidation in calvaria cells cultured with diphosphonates. 1981 Biochem. J. pmid:6458286
Burns AH and Reddy WJ Effect of ouabain on exogenous substrate oxidation by isolated cardiac myocytes. 1981 Res. Commun. Chem. Pathol. Pharmacol. pmid:6267674
Seydoux J et al. Functional disconnection of brown adipose tissue in hypothalamic obesity in rats. 1981 Pflugers Arch. pmid:7195549
Hollander D Retinol lymphatic and portal transport: influence of pH, bile, and fatty acids. 1980 Am. J. Physiol. pmid:7435575
Kössler F et al. [Effect of homologous n-alkanoic acids on the function of isolated skeletal muscles. V. Relations between twitch, tetanus and contracture]. 1980 Acta Biol. Med. Ger. pmid:7445906
Nesher R et al. Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. 1980 Am. J. Physiol. pmid:7446724
Bartels PD and Sestoft L Thyroid hormone-induced changes in gluconeogenesis and ketogenesis in perfused rat liver. 1980 Biochim. Biophys. Acta pmid:7448206
Zammit VA The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria. 1980 Biochem. J. pmid:7470052